Title: Top Independent in Mesopotamia from $63 - Expedia.com

[Mesopotamia Travel Guide](https://expedia.com/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.com/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.com/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.com/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Car Rentals in Mesopotamia](https://expedia.com/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.com/Mesopotamia.d6208836.Destination-Travel-Guides)

![Iguazu Falls featuring a waterfall](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=6208836&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 28 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6208836&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6208836&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6208836&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mesopotamia Independent

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/ab1ba3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/212e6606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/892799c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/35a3b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson Plaza La Ribera

[](https://www.expedia.com/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information)

Resistencia

9.4/10

Exceptional

(140 reviews)

"The staff were exceptional. Jessica was extremely kind, and always had ice prepared for us after noticing that we had requested it twice. She was such a kind face at the front of the hotel and made our experience wonderful"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Natalia

[](https://www.expedia.com/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/b318b64f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna](https://images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/c420d4ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/7ac5e90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, hot stone massages, massages](https://images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/f09e615e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Zarate

[](https://www.expedia.com/Zarate-Hotels-Days-Inn-Zarate.h71042838.Hotel-Information)

Zárate

8.4/10

Very Good

(101 reviews)

"Room with very comfortable beds, which is the hotel's strongest point, service by the guys at breakfast very bad, no desire to work, bathroom located on the ground floor with a smell worse than a public bathroom in the city center, where I have already informed the management so that they can take action. Very nice pool for families. Good hotel for families on vacation and good breakfast!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ALEXANDER

[](https://www.expedia.com/Zarate-Hotels-Days-Inn-Zarate.h71042838.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/903afdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/904442d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/6ec7ef75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/09bc75f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterTower Hotel

[](https://www.expedia.com/Santa-Fe-Hotels-InterTower-Hotel.h9845278.Hotel-Information)

Santa Fe

8.8/10

Excellent

(219 reviews)

"Welcoming staff, clean room and good breakfast. Good location and staff arranged transport to airport."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephen

$103 nightly

$103 total

Feb 28 - Mar 1

[](https://www.expedia.com/Santa-Fe-Hotels-InterTower-Hotel.h9845278.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/9eccf106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e4c32829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Puerto Norte Design Hotel

[](https://www.expedia.com/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

Rosario

9.2/10

Wonderful

(147 reviews)

"Nice place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos

[](https://www.expedia.com/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/25000000/25000000/24990500/24990493/e4ab3ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/25000000/25000000/24990500/24990493/2ed944b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Twin Room, 2 Twin Beds, Non Smoking | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/25000000/25000000/24990500/24990493/ffbc7d25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/25000000/25000000/24990500/24990493/a3f4ea5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Continental Posadas Hotel

[](https://www.expedia.com/Posadas-Hotels-Continental-Posadas-Hotel.h24990493.Hotel-Information)

Posadas

7.8/10

Good

(101 reviews)

"Nice hotel on plaza 9 d Julio with a excellent gelateria"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

[](https://www.expedia.com/Posadas-Hotels-Continental-Posadas-Hotel.h24990493.Hotel-Information)

![Executive Suite | Balcony](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993113/f19aa4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993113/11e61f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Spa](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993113/bfd7c392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993113/b490b856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Maitei Posadas

[](https://www.expedia.com/Posadas-Hotels-Avenida-Ulises-Lopez.h95993113.Hotel-Information)

Posadas

7.6/10

Good

(49 reviews)

"Very old mattresses, not comfortable sleeping, parts of the building seems abandoned "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fredy

$65 nightly

$67 total

Feb 28 - Mar 1

[](https://www.expedia.com/Posadas-Hotels-Avenida-Ulises-Lopez.h95993113.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/4ee385b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/w5616h3309x0y0-f51e8961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/62c5f089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/2c7dcd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Los Silos Hotel

[](https://www.expedia.com/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information)

Santa Fe

9.4/10

Exceptional

(31 reviews)

"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Russell

$123 nightly

$123 total

Mar 1 - Mar 2

[](https://www.expedia.com/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/37467e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Hypo-allergenic bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/772c4583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/a11b7965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Senior Room | Hypo-allergenic bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/765f8094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Garden Campana

[](https://www.expedia.com/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information)

Campana

7.2/10

Good

(105 reviews)

"okay for shortterm stay"

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Sebastian

[](https://www.expedia.com/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12380000/12370700/12370608/286a3d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/13000000/12380000/12370700/12370608/b5351e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/13000000/12380000/12370700/12370608/de16aaf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/13000000/12380000/12370700/12370608/380e240b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gala Hotel y Convenciones

[](https://www.expedia.com/Resistencia-Hotels-Gala-Hotel-Y-Convenciones.h12370608.Hotel-Information)

Resistencia

9.2/10

Wonderful

(154 reviews)

"Close to the airport. Great price and luxurious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JONATHAN

$63 nightly

$63 total

Feb 28 - Mar 1

[](https://www.expedia.com/Resistencia-Hotels-Gala-Hotel-Y-Convenciones.h12370608.Hotel-Information)

![Casino](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/d4a9979b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/0fd9db67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/03eec10d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/a62c82fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pullman Rosario City Center Hotel

[](https://www.expedia.com/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

Rosario

8.6/10

Excellent

(277 reviews)

"Nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

juan

[](https://www.expedia.com/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Mesopotamia Hotel Reviews

![Casa del Árbol](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/bc43cf92_y.jpg)

### Casa del Árbol

2/10 Terrible

"La plataforma por.donde contrate te reserva aunque no haya lugar en el hostel Un desastre todo. No tienen verguenza. Poco serio "

[](https://expedia.com/Concepcion-Del-Uruguay-Hotels-Casa-Del-Arbol.h36653372.Hotel-Information)

![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg)

### Marriott Corrientes Hotel

10/10 Excellent

"Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable."

[](https://expedia.com/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information)

![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg)

### Holiday Inn Rosario by IHG

10/10 Excellent

"Hermosa estadía en el hotel. Todo impecable! El personal del hotel Maravilloso. Súper recomendable. Gracias por todo. Volveremos.."

[](https://expedia.com/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information)

![Intersur Colon](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56_y.jpg)

### Intersur Colon

6/10 Okay

"Is ok "

[](https://expedia.com/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information)

![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg)

### Holiday Inn Express Rosario by IHG

10/10 Excellent

"Clean room. Very nice staffing. Very good breakfast "

[](https://expedia.com/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information)

![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg)

### Hathor Concordia

10/10 Excellent

"The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"."

[](https://expedia.com/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information)

![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg)

### Club Valle Termal Resort

10/10 Excellent

"La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto."

[](https://expedia.com/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information)

![Mayim Hotel Termal & SPA](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/182c3232_y.jpg)

### Mayim Hotel Termal & SPA

8/10 Good

"Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación "

[](https://expedia.com/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information)

![Costarenas Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg)

### Costarenas Hotel & Spa

2/10 Terrible

"Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. "

[](https://expedia.com/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information)

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