Mesopotamia Adventure Vacations
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Top Adventure vacation packages in Mesopotamia
Price found within the past 48 hours. Click for updated prices.
Iguazu Grand Resort Spa & Casino
Price was $796, price is now $513 per person
$513
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9/10 Wonderful! (581 reviews)
This is a really wonderful hotel. Before my arrival the lovely concierge texted me to make sure they were prepared for my stay and graciously answered all my questions. I was given a wonderful room that faced their gorgeous pool area. The service at the hotel is flawless from the front desk, concierge to restaurant and spa services I utilized all perfect. The grounds are stunning. It is a great place to stay if you are visiting Iganzu Falls! I really enjoyed my time there!
Reviewed on Dec 12, 2025
Gran Melia Iguazú
Save 100% on your flight
Price was $1,903, price is now $1,091 per person
$1,091
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,002 reviews)
You won't regret choosing this hotel. The location is remarkable, the views are mind blowing, the hotel itself is fantastic, and the staff goes above and beyond every step of the way. The only negative was not having time to stay longer.
Reviewed on Dec 13, 2025
Loi Suites Iguazú Hotel
Save 100% on your flight
Price was $913, price is now $622 per person
$622
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A near-perfect mini-resort tucked away into the rain forest. Staying at the Loi made our trip to the Iguazu Falls a truly fantastic getaway.
Reviewed on Dec 13, 2025
Posada Puerto Bemberg
Price was $896, price is now $725 per person
$725
per person
Feb 28 - Mar 4
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.8/10 Exceptional! (15 reviews)
The setting was excellent and location was very special but the food was very average.
Reviewed on Feb 24, 2020
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See all available trips from Columbus to Mesopotamia
View all trips5* Adventure vacations in Mesopotamia
Price found within the past 48 hours. Click for updated prices.
Iguazu Grand Resort Spa & Casino
Price was $796, price is now $513 per person
$513
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9/10 Wonderful! (581 reviews)
This is a really wonderful hotel. Before my arrival the lovely concierge texted me to make sure they were prepared for my stay and graciously answered all my questions. I was given a wonderful room that faced their gorgeous pool area. The service at the hotel is flawless from the front desk, concierge to restaurant and spa services I utilized all perfect. The grounds are stunning. It is a great place to stay if you are visiting Iganzu Falls! I really enjoyed my time there!
Reviewed on Dec 12, 2025
Gran Melia Iguazú
Save 100% on your flight
Price was $1,903, price is now $1,091 per person
$1,091
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,002 reviews)
You won't regret choosing this hotel. The location is remarkable, the views are mind blowing, the hotel itself is fantastic, and the staff goes above and beyond every step of the way. The only negative was not having time to stay longer.
Reviewed on Dec 13, 2025
Loi Suites Iguazú Hotel
Save 100% on your flight
Price was $913, price is now $622 per person
$622
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A near-perfect mini-resort tucked away into the rain forest. Staying at the Loi made our trip to the Iguazu Falls a truly fantastic getaway.
Reviewed on Dec 13, 2025
Don't see what you're looking for?
See all available trips from Columbus to Mesopotamia
View all trips3 Night Adventure vacations in Mesopotamia
Price found within the past 48 hours. Click for updated prices.
Iguazu Grand Resort Spa & Casino
Price was $796, price is now $513 per person
$513
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9/10 Wonderful! (581 reviews)
This is a really wonderful hotel. Before my arrival the lovely concierge texted me to make sure they were prepared for my stay and graciously answered all my questions. I was given a wonderful room that faced their gorgeous pool area. The service at the hotel is flawless from the front desk, concierge to restaurant and spa services I utilized all perfect. The grounds are stunning. It is a great place to stay if you are visiting Iganzu Falls! I really enjoyed my time there!
Reviewed on Dec 12, 2025
Gran Melia Iguazú
Save 100% on your flight
Price was $1,903, price is now $1,091 per person
$1,091
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,002 reviews)
You won't regret choosing this hotel. The location is remarkable, the views are mind blowing, the hotel itself is fantastic, and the staff goes above and beyond every step of the way. The only negative was not having time to stay longer.
Reviewed on Dec 13, 2025
Falls Iguazú Hotel & Spa
Save 100% on your flight
Price was $894, price is now $595 per person
$595
per person
Mar 4 - Mar 7
found 8 hours ago
Roundtrip flight included
Buenos Aires (EZE) to Iguazu (IGR)
9.2/10 Wonderful! (455 reviews)
Hotel was clean great service very little English spoken!
Reviewed on Dec 3, 2025
Don't see what you're looking for?
See all available trips from Columbus to Mesopotamia
View all trips4 Night Adventure vacations in Mesopotamia
Price found within the past 48 hours. Click for updated prices.
Iguazu Grand Resort Spa & Casino
Price was $1,242, price is now $832 per person
$832
per person
Feb 28 - Mar 4
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9/10 Wonderful! (581 reviews)
This is a really wonderful hotel. Before my arrival the lovely concierge texted me to make sure they were prepared for my stay and graciously answered all my questions. I was given a wonderful room that faced their gorgeous pool area. The service at the hotel is flawless from the front desk, concierge to restaurant and spa services I utilized all perfect. The grounds are stunning. It is a great place to stay if you are visiting Iganzu Falls! I really enjoyed my time there!
Reviewed on Dec 12, 2025
Gran Melia Iguazú
Save 100% on your flight
Price was $3,225, price is now $1,943 per person
$1,943
per person
Feb 28 - Mar 4
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.2/10 Wonderful! (1,002 reviews)
You won't regret choosing this hotel. The location is remarkable, the views are mind blowing, the hotel itself is fantastic, and the staff goes above and beyond every step of the way. The only negative was not having time to stay longer.
Reviewed on Dec 13, 2025
Loi Suites Iguazú Hotel
Price was $1,387, price is now $972 per person
$972
per person
Feb 28 - Mar 4
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A near-perfect mini-resort tucked away into the rain forest. Staying at the Loi made our trip to the Iguazu Falls a truly fantastic getaway.
Reviewed on Dec 13, 2025
Don't see what you're looking for?
See all available trips from Columbus to Mesopotamia
View all tripsFind awesome Mesopotamia adventure vacations
How can I book the best Mesopotamia adventure trips?
Choose your own adventure in Mesopotamia, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun.
How can I plan the perfect Mesopotamia family adventure vacation?
Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Mesopotamia. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning.
Can I book all-inclusive Mesopotamia adventure vacation packages?
By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway.
Why should I book a Mesopotamia adventure vacation for couples?
Book a Mesopotamia couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond.
How can I find the best deals on adventure packages in Mesopotamia?
It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals.
Can I book an adventure vacation package in Mesopotamia with free cancellation and/or flexible dates?
Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility.
Why should I book a Mesopotamia adventure trip with Expedia?
Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A.
Top Adventure Mesopotamia Hotels
Iguazu Grand Resort Spa & Casino
Route 12 Km 1640 Puerto Iguazú Misiones
Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (585 reviews)
Clean room; Friendly staff; Need some improvement on decorations; Great amenities; A little far from main downtown for anyone wanting to be next to the action.
Reviewed on Nov 21, 2025
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32 Foz do Iguaçu PR
Book a stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (1,006 reviews)
We loved this hotel and its access to the falls. We took a dawn hike at 5am and had the park to ourselves. This was the highlight of our trip to Brazil.
Reviewed on Dec 7, 2025
Gran Melia Iguazú
Parque Nacional Iguazu Puerto Iguazú Misiones
Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
Great stay with a great view!
Reviewed on Dec 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
