Title: Mesopotamia Vacation Packages 2026 from $661 | Expedia.com

[Mesopotamia Travel Guide](https://expedia.com/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.com/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.com/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.com/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Car Rentals in Mesopotamia](https://expedia.com/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Mesopotamia Vacations from $661

## Book a Hotel + Flight or Car together to unlock savings

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### Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with [Corrientes](https://www.expedia.com/Corrientes.d6054203.Destination-Travel-Guides). Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. [Concordia](https://www.expedia.com/Concordia.d892.Destination-Travel-Guides) is another favorite with Mesopotamia travelers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're traveling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

## The Latest Mesopotamia vacation packages

Price found within the past 48 hours. Click for updated prices.

![Apartments Bariloche - Deco Recoleta](https://images.trvl-media.com/lodging/102000000/101950000/101945800/101945732/c39f1c7c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Apartments Bariloche - Deco Recoleta

Recoleta

$661

per person

May 7 - May 12

found 10 hours ago

Roundtrip non-stop flight included

San José (SJO) to Buenos Aires (EZE)

9.4/10 Exceptional! (69 reviews)

Great place, great location, great amenities,

Reviewed on Mar 22, 2026

![Mio Buenos Aires](https://images.trvl-media.com/lodging/5000000/4270000/4260900/4260897/ab1143f6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Mio Buenos Aires

Recoleta

Save 100% on your flight

$1,228

per person

May 7 - May 12

found 10 hours ago

Roundtrip non-stop flight included

San José (SJO) to Buenos Aires (EZE)

9.4/10 Exceptional! (605 reviews)

Good location and helpful doorstaff

Reviewed on Mar 31, 2026

![Casa Lucia Member of Melia Collection](https://images.trvl-media.com/lodging/96000000/95560000/95550400/95550354/f15dde32_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Casa Lucia Member of Melia Collection

El Centro

Save 100% on your flight

$1,349

per person

Jun 15 - Jun 22

found 7 hours ago

Roundtrip non-stop flight included

San Juan (SJU) to Buenos Aires (EZE)

9.6/10 Exceptional! (128 reviews)

Very nice hotel, excellent location, great staff. Our flight back home was delayed for 48 hours, and Guadalupe and Kevin from the hotel Front Desk were of great help in sorting out this problem. The hotel has a very nice restaurant. Our waiter, Sara provided great service

Reviewed on Mar 20, 2026

![Casa Umare](https://images.trvl-media.com/lodging/20000000/19070000/19062000/19061954/ea807346_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Casa Umare

Almagro

$898

per person

May 15 - May 22

found 1 day ago

Roundtrip non-stop flight included

San José (SJO) to Buenos Aires (EZE)

9.6/10 Exceptional! (87 reviews)

Casa Umare is beautiful. The

Reviewed on May 8, 2025

![Howard Johnson by Wyndham Ezeiza Convention Center](https://images.trvl-media.com/lodging/7000000/6780000/6771300/6771293/e8d58ca2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Howard Johnson by Wyndham Ezeiza Convention Center

$794

per person

May 15 - May 22

found 1 day ago

Roundtrip non-stop flight included

San José (SJO) to Buenos Aires (EZE)

7.2/10 Good! (288 reviews)

Easy check 9n nice clean room. Roads from airport to hotel is very rough and bumpy

Reviewed on Feb 22, 2026

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-03/2026-05-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=AOL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

### Discover the most popular places to visit in Mesopotamia

![Parque Nacional El Palmar, Entre Rios, Argentina.](https://images.trvl-media.com/place/6096826/3ac30eef-b699-482d-95ce-e991c872d599.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay. 

[](https://expedia.com/El-Palmar-National-Park-Ubajay.d6096826.Vacation-Attraction)

![Parroquia Nuestra Señora de Itati](https://images.trvl-media.com/place/553248621532463967/dcc3f703-5a3b-46d8-99a7-83b2e87b8ea0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati. 

[](https://expedia.com/Basilica-Nuestra-Senora-De-Itati-Municipo-de-Itati.d553248621532463967.Vacation-Attraction)

![Punta San Sebastian, Corrientes, Costanera Corrientes](https://images.trvl-media.com/place/553248621532463961/5eccf4f4-bdb0-4368-8beb-0fffd1c8eab0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Costanera de Corrientes

Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area. 

[](https://expedia.com/Costanera-De-Corrientes-Corrientes.d553248621532463961.Vacation-Attraction)

## Mesopotamia Hotel Deals

![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Marriott Corrientes Hotel

Av Costanera Juan Pablo II y Lavalle Corrientes 

Fully refundableReserve now, pay when you stay

$116 nightly

$116 total

Apr 12 - Apr 13

10/10 Exceptional! (24 reviews)

I had a great experience at this Marriott hotel in Corrientes. The property is exactly as described — beautiful, well-maintained, and with an excellent location. I stayed there for a wedding, and everything was outstanding. The service was incredible from start to finish, and the staff was always ...

Reviewed on Mar 24, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=117154160&PinnedHotelID=117154160&HadPinnedHotel=true&regionId=6208836)

![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos

Fully refundableReserve now, pay when you stay

$50 nightly

$50 total

Apr 5 - Apr 6

7.6/10 Good! (81 reviews)

Nice

Reviewed on Apr 2, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=76459363&PinnedHotelID=76459363&HadPinnedHotel=true&regionId=6208836)

![Turismo Hotel Casino](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/a0b30be4_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Turismo Hotel Casino

650 Entre Ríos Corrientes Corrientes

Fully refundableReserve now, pay when you stay

$103 nightly

$103 total

Apr 19 - Apr 20

8/10 Very Good! (4 reviews)

Boa infraestrutura, e localização!

Reviewed on Feb 4, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F19%2F2026&endDate=4%2F20%2F2026&selected=120517502&PinnedHotelID=120517502&HadPinnedHotel=true&regionId=6208836)

[See all 507 properties in Mesopotamia](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F4%2F2026&endDate=4%2F5%2F2026&regionId=6208836)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Mesopotamia Vacation Packages

## Mesopotamia Essential Information

| Language        | Spanish                                |
| --------------- | -------------------------------------- |
| Currency        | Argentine pesos                        |
| Local Welcome   | ¡Hola!                                 |
| Local Goodbye   | Adiós                                  |
| Closest Airport | Ministro Pistarini Intl. Airport (EZE) |

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\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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