A large, historic church with a tall bell tower and multiple domes.

Find 4 Star Hotels in Opelousas, LA from $104

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Opelousas 4 Star Hotels

This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Our top choices for Opelousas 4-star hotels

Nightclub

1. DoubleTree by Hilton Hotel Lafayette

DoubleTree by Hilton Hotel Lafayette
4.0 star property
Lafayette
8.6 out of 10, Excellent, (1,003 reviews)
"Always great place to stay."
United States
Kimberly
$90 nightly
The price is $104
Aug 17 - Aug 18
Total with taxes and fees
DoubleTree by Hilton Hotel Lafayette
Luxury Townhome, 3 Bedrooms, Kitchen | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

2. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
4.0 star property
Lafayette
$224 nightly
The price is $244
Aug 6 - Aug 7
Total with taxes and fees
Enclave 3 Bedroom Luxury Homes
Room, Private Bathroom (Country Garden Cottage) | Laptop workspace, iron/ironing board, WiFi (free)

3. Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
4.0 star property
Rayne
9.6 out of 10, Exceptional, (97 reviews)
"Delightful bed and breakfast venue. Real Southern charm and Lynn (the owner) was a fantastic host. Far exceeded our expectations and genuinely wished we could have stayed longer."
United Kingdom
Paul
$174 nightly
The price is $197
Aug 5 - Aug 6
Total with taxes and fees
Maison D'Memoire Bed & Breakfast Cottages
Luxury House, 2 Bedrooms, Non Smoking, Kitchen | Living area | Smart TV

4. The Royal Inn

The Royal Inn
4.0 star property
Lafayette
$235 nightly
The price is $256
Aug 5 - Aug 6
Total with taxes and fees
The Royal Inn
Luxury House, 2 Bedrooms, Non Smoking, Kitchen | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

5. Esplanade Inn

Esplanade Inn
4.0 star property
Lafayette
$224 nightly
The price is $244
Aug 5 - Aug 6
Total with taxes and fees
Esplanade Inn
Luxury House, 2 Bedrooms, Kitchen | Living area

6. Canal Inn

Canal Inn
4.0 star property
Lafayette
Canal Inn
Luxury House, 3 Bedrooms, Non Smoking, Pets Allowed | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

7. Decatur Inn

Decatur Inn
4.0 star property
Lafayette
$243 nightly
The price is $265
Aug 5 - Aug 6
Total with taxes and fees
Decatur Inn
Luxury House, 3 Bedrooms, Non Smoking, Pets Allowed | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

8. Rampart Inn

Rampart Inn
4.0 star property
Lafayette
Rampart Inn
Luxury House, 2 Bedrooms, Non Smoking, Kitchen | Living area | Smart TV

9. Canal Inn

Canal Inn
4.0 star property
Lafayette
$221 nightly
The price is $241
Aug 5 - Aug 6
Total with taxes and fees
Canal Inn
Luxury House, 2 Bedrooms, Non Smoking, Kitchen | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

10. Poydras Inn

Poydras Inn
4.0 star property
Lafayette
$229 nightly
The price is $250
Aug 5 - Aug 6
Total with taxes and fees
Poydras Inn
Luxury House | Private kitchen | Coffee/tea maker, full-size fridge, microwave, oven

11. Iberville Inn

Iberville Inn
4.0 star property
Lafayette
$233 nightly
The price is $254
Aug 5 - Aug 6
Total with taxes and fees
Iberville Inn
Lobby

12. Wyndham Garden Lafayette

Wyndham Garden Lafayette
4.0 star property
Lafayette
5.4 out of 10, (548 reviews)
"The carpets need to be steamed clean . The housekeeper didn’t gave us towels like they was supposed to . We had to call like 3x before the front desk had to come bring the towels . They never emptied the garbage the whole two days we was there. The air condition needed to be turned up . They need microwaves in the rooms. The rooms are nice besides no microwave. I enjoyed my stay but they need to upgrade the freshness and upgrade on their housekeeping service"
United States
Anonymous traveler
Wyndham Garden Lafayette
Exterior

13. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
4.0 star property
Lafayette
Enclave 3 Bedroom Luxury Homes
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Opelousas

Spice up your visit to the Zydeco Capital with live music venues and the annual Zydeco Festival in late August. Explore Cajun food history at the Opelousas Museum, then sample authentic boudin and crawfish at family-owned restaurants locals recommend.

See all hotels in Opelousas
A large, historic church with a tall bell tower and multiple domes.

Top Opelousas Hotel Reviews

Find out more about Opelousas

Opelousas Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Opelousas, Louisiana are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Opelousas 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Opelousas. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Opelousas, Louisiana, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Opelousas hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Opelousas?
To book a 4-star hotel in Opelousas that matches your budget, take advantage of Expedia's handy filter tool. Check out what's available during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the most budget-friendly escape first.

  • Search for the lowest price from $104

What's the difference between 5-star and 4-star hotels in Opelousas?
Treat yourself to refined living during your Opelousas escape by staying at a 4-star hotel. As well as featuring upmarket accommodations, these properties are typically filled with amenities such as bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and unforgettable one. 24-hour concierge assistance, on-site spas and world-class dining are a few of the exclusive services and conveniences you'll likely get access to.
Does Opelousas have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your next getaway in Opelousas where just about everything is taken care of, from your accommodations to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this sought-after destination.

Explore a world of travel with Expedia