A large, historic church with a tall bell tower and multiple domes.

Find 4 Star Hotels in Opelousas, LA from $103

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Check availability on Opelousas 4 Star Hotels

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Opelousas 4-star hotels

A bar area with a long counter, multiple bar stools, shelves with bottles, and a TV mounted above the bar.
A hotel room with a bed, a TV, a desk, a chair, a desk lamp, a bedside table with a lamp, a bathtub, and a window with curtains.
A hotel lobby with a grand staircase, a buffet table with floral centerpieces, and elegant lighting fixtures.
A spacious lobby with a staircase, seating area, and a reception desk.

1. DoubleTree by Hilton Hotel Lafayette

DoubleTree by Hilton Hotel Lafayette
Lafayette
United States
Tager
$89 nightly
$103 total
Oct 25 - Oct 26
Total with taxes and fees
DoubleTree by Hilton Hotel Lafayette
A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.
A row of modern townhouses with attached garages, a clear sky, and a well-maintained lawn.
A modern two-story residential building with a garage, a small front yard, and a clear sky.
A neatly made bed with a headboard, two bedside tables with lamps, a wall-mounted artwork, and a window with blinds.

2. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
Lafayette
United States
Roderick
$222 nightly
$242 total
Sep 29 - Sep 30
Total with taxes and fees
Enclave 3 Bedroom Luxury Homes
A small, single-story house with a porch and a wooden fence.
A dining area with a table set for two, a vase with flowers, and a painting on the wall.
A sunlit room with a table, two chairs, a vase with flowers, and a view of a green landscape through large windows.
A wooden sign with the text "Prairie Haven Cottage".

3. Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
Rayne
United Kingdom
Paul
$181 nightly
$205 total
Oct 21 - Oct 22
Total with taxes and fees
Maison D'Memoire Bed & Breakfast Cottages
A modern kitchen with white cabinetry, gold handles, a built-in microwave, and a stove.
A bedroom with a bed, bedside tables, a wall-mounted artwork, a window with blinds, and a door.
Two white Whirlpool washing machines in a laundry room with a shelf above containing cleaning supplies.
A modern living room with a sofa, coffee table, and dining area.

4. Decatur Inn

Decatur Inn
Lafayette
$244 nightly
$266 total
Sep 29 - Sep 30
Total with taxes and fees
Decatur Inn
A spacious living area with a dining table, sofa, and a ceiling fan.
A wooden deck with a railing, two rocking chairs, and a view of a road and trees.
A modern, well-lit room with a dining table, wicker chairs, a sofa, and a large mirror on the wall.
A modern kitchen with white cabinets, stainless steel appliances, a wooden cart, and a dining area with a chair.

5. The Royal Inn

The Royal Inn
Lafayette
United States
Yudeika
$217 nightly
$237 total
Sep 29 - Sep 30
Total with taxes and fees
The Royal Inn
A modern kitchen with white cabinetry, a central island with seating, a microwave, stove, and refrigerator.
A pink building with a white door, a window with blinds, and the number 219.
A bedroom with a bed, a nightstand, a dresser, and a painting on the wall.
A laundry room with two Whirlpool washers, a small shelf with cleaning supplies, and a door leading to a bedroom with a bed and nightstand.

6. Esplanade Inn

Esplanade Inn
Lafayette
$228 nightly
$249 total
Oct 12 - Oct 13
Total with taxes and fees
Esplanade Inn
A spacious living area with a round dining table, a sofa, and a painting of a lake.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining area.
A wooden deck with a railing, a rocking chair, and a building with large windows.
A neatly made bed with a striped pillow, two bedside tables with lamps, and a framed picture on the wall.

7. Canal Inn

Canal Inn
Lafayette
Canal Inn
A spacious living area with a round dining table, a sofa, and a painting of a lake.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining area.
A two-story house with a balcony, a garage, and a driveway.
A neatly made bed with a striped pillow, two bedside tables with lamps, and a framed picture on the wall.

8. Canal Inn

Canal Inn
Lafayette
$219 nightly
$238 total
Oct 8 - Oct 9
Total with taxes and fees
Canal Inn

9. Wyndham Garden Lafayette

Wyndham Garden Lafayette
Lafayette
United States
Anonymous traveler
Wyndham Garden Lafayette
A modern kitchen with white cabinets, stainless steel appliances, and a round wooden table with wicker chairs.
A modern apartment with a kitchen, dining area, and living room.
A bedroom with a bed, pillows, a window with blinds, a painting, and a view of greenery.
A modern living room with a sofa, two armchairs, a coffee table, and a rug.

10. Rampart Inn

Rampart Inn
Lafayette
$237 nightly
$258 total
Sep 29 - Sep 30
Total with taxes and fees
Rampart Inn
A modern kitchen with white cabinetry, a central island with seating, a microwave, stove, and refrigerator.
A laundry room with two Whirlpool washers, a small shelf with cleaning supplies, and a door leading to a bedroom with a bed and nightstand.
A pink building with a white door, a window with blinds, and the number 219.
A modern kitchen with white cabinets, a central island with bar stools, a gray sofa, and a round coffee table.

11. Poydras Inn

Poydras Inn
Lafayette
$233 nightly
$254 total
Sep 28 - Sep 29
Total with taxes and fees
Poydras Inn
A modern kitchen with white cabinets, stainless steel appliances, a dishwasher, and a dining area with wicker chairs.
A modern kitchen with white cabinets, a microwave, and a refrigerator. There is a dining area with a round table and chairs. A beige sofa is in the living room with a patterned rug.
A laundry room with two front-loading washers, a dining area with chairs, and a hallway leading to another room.
A bedroom with a bed, a nightstand, a lamp, a painting on the wall, and a door leading to a bathroom.

12. Iberville Inn

Iberville Inn
Lafayette
Iberville Inn
A row of modern multi-story residential buildings with attached garages, set against a backdrop of a grassy landscape and clear blue sky.
A modern kitchen with white cabinets, a central island with blue chairs, and stainless steel appliances.
A bedroom with a white bed, two nightstands, a ceiling fan, a window with blinds, and a mirror.
A modern bathroom with a white shower curtain, a white toilet, a vanity with a marble countertop, and a black faucet.

13. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
Lafayette
Enclave 3 Bedroom Luxury Homes
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Learn more about Opelousas

Spice up your visit to the Zydeco Capital with live music venues and the annual Zydeco Festival in late August. Explore Cajun food history at the Opelousas Museum, then sample authentic boudin and crawfish at family-owned restaurants locals recommend.

See all hotels in Opelousas
A large, historic church with a tall bell tower and multiple domes.

Top Opelousas Hotel Reviews

Find out more about Opelousas

Opelousas Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Opelousas, Louisiana are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Opelousas 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Opelousas. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Opelousas, Louisiana, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Opelousas hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Opelousas?
To book a 4-star hotel in Opelousas that matches your budget, take advantage of Expedia's handy filter tool. Check out what's available during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the most budget-friendly escape first.
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What's the difference between 5-star and 4-star hotels in Opelousas?
Treat yourself to refined living during your Opelousas escape by staying at a 4-star hotel. As well as featuring upmarket accommodations, these properties are typically filled with amenities such as bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and unforgettable one. 24-hour concierge assistance, on-site spas and world-class dining are a few of the exclusive services and conveniences you'll likely get access to.
Does Opelousas have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your next getaway in Opelousas where just about everything is taken care of, from your accommodations to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this sought-after destination.

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