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Check availability on Southeastern Indiana 4 Star Hotels

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Southeastern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A balcony with a view of a river, a bridge, and a cityscape.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Mark
$145 nightly
$171 total
Oct 25 - Oct 26
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Samantha
$125 nightly
$148 total
Oct 18 - Oct 19
Total with taxes and fees
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, large windows, and classic furniture.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
John
$156 nightly
$183 total
Oct 28 - Oct 29
Total with taxes and fees
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.
A hotel dining area with long tables, booths, and a bar.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
$130 nightly
$153 total
Nov 15 - Nov 16
Total with taxes and fees
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.
A reception area with a wooden wall and a neon sign that reads "Sway LOCAL SOUTHERN EATERY".
A modern indoor swimming pool with clear glass walls, lounge chairs, and a wooden wall in the background.
A bar area with wooden paneling, multiple seating arrangements, and a variety of liquor bottles displayed on shelves.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Lester
$165 nightly
$194 total
Oct 29 - Oct 30
Total with taxes and fees
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Veronica
$137 nightly
$162 total
Nov 13 - Nov 14
Total with taxes and fees
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
$156 nightly
$184 total
Nov 8 - Nov 9
Total with taxes and fees
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A brightly lit grocery store with yellow shelving and a central checkout counter.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
$135 nightly
$159 total
Oct 25 - Oct 26
Total with taxes and fees
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Heather
$237 nightly
$279 total
Oct 29 - Oct 30
Total with taxes and fees
Hotel Distil, Autograph Collection
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A building with a sign reading "THE GRADY" at the entrance.

10. The Grady

The Grady
Downtown Louisville
United States
Donna
$173 nightly
$204 total
Nov 15 - Nov 16
Total with taxes and fees
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
$180 nightly
$211 total
Oct 25 - Oct 26
Total with taxes and fees
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A grand lobby with marble floors, a staircase, and a reception desk.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.
A bakery display with pastries and bread, a coffee station, and a Christmas tree in the background.

12. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Colleen
$165 nightly
$194 total
Oct 29 - Oct 30
Total with taxes and fees
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

13. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
$160 nightly
$186 total
Oct 29 - Oct 30
Total with taxes and fees
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A covered porch with a brick wall, a wooden door, and a hanging light fixture.
A long table set with white tablecloths, gold chargers, and clear glassware.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
David
$115 nightly
$130 total
Nov 3 - Nov 4
Total with taxes and fees
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A narrow corridor with exposed brick walls, wooden flooring, and a seating area with tables and chairs.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.

15. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.
A multi-story residential building with balconies, a brick facade, and large windows.

16. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
$194 nightly
$225 total
Oct 18 - Oct 19
Total with taxes and fees
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
Terrace/patio
Private kitchen
In-room dining

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
$159 nightly
$180 total
Oct 17 - Oct 18
Total with taxes and fees
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.
A large outdoor swimming pool with a Ferris wheel in the background.

18. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.

19. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
A grand hotel with a prominent tower, multiple staircases, and a well-lit entrance.
A large, multi-level atrium with a central circular area, surrounded by multiple floors of rooms with balconies.
A spacious indoor area with a high ceiling and large windows, featuring a central decorative column and a dining area with tables and chairs.
A grand hotel lobby with a high ceiling, large windows, and a central courtyard with seating areas.

20. West Baden Springs Hotel

West Baden Springs Hotel
West Baden Springs
United States
Anonymous traveler
West Baden Springs Hotel
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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southeastern Indiana Hotel Reviews

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Southeastern Indiana Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southeastern Indiana, United States of America are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southeastern Indiana 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southeastern Indiana. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southeastern Indiana, United States of America, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southeastern Indiana hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You can find a range of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a customer favorite in this city that offers a swimming pool and massage services. Another getaway that gets excellent reviews from travelers is Hyatt Regency Louisville. Designer toiletries and a swimming pool help make it their number one choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
To find a 4-star hotel in Southeastern Indiana that fits your budget, make use of Expedia's handy search filters. Browse the available options during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most wallet-friendly escape first.
  • Search for the lowest price from $130
What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
Treat yourself to luxury living during your Southeastern Indiana vacation by staying at a 4-star hotel. As well as featuring upscale accommodations, these properties are typically packed with amenities like complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and unforgettable one. Round-the-clock concierge assistance, luxurious spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.

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