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Our top choices for Southeastern Indiana 4-star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3959)
"Great place to stay! "
United States
Rochelle
$125 nightly
The price is $148
Jan 24 - Jan 25
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1759)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
$167 nightly
The price is $197
Jan 24 - Jan 25
Total with taxes and fees
Omni Louisville Hotel

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1144)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
$114 nightly
The price is $134
Jan 18 - Jan 19
Total with taxes and fees
Embassy Suites Louisville Downtown

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1170)
"Fantastic place to stay in Louisville."
United States
Nathaniel
$168 nightly
The price is $198
Jan 6 - Jan 7
Total with taxes and fees
The Brown Hotel

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1023)
"Everything was perfect. Beautiful hotel. We enjoyed our stay."
United States
Serena
$110 nightly
The price is $129
Jan 12 - Jan 13
Total with taxes and fees
Hotel Genevieve part of JdV by Hyatt

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1001)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
$125 nightly
The price is $147
Jan 6 - Jan 7
Total with taxes and fees
21c Museum Hotel Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1008)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
$146 nightly
The price is $172
Jan 16 - Jan 17
Total with taxes and fees
Hyatt Regency Louisville

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1015)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
$161 nightly
The price is $189
Jan 12 - Jan 13
Total with taxes and fees
The Grady

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
$171 nightly
The price is $201
Jan 17 - Jan 18
Total with taxes and fees
Louisville Marriott Downtown

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (431)
"Clean, well appointed, convenient to restaurants and downtown Louisville."
United States
Chris
$184 nightly
The price is $216
Jan 19 - Jan 20
Total with taxes and fees
Hotel Distil, Autograph Collection

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (60)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
$168 nightly
The price is $198
Jan 12 - Jan 13
Total with taxes and fees
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1002)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
$148 nightly
The price is $174
Jan 8 - Jan 9
Total with taxes and fees
Seelbach Hilton Louisville Downtown

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (118)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
$146 nightly
The price is $170
Jan 21 - Jan 22
Total with taxes and fees
Stellar Suites

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (650)
"This is our second visit this year. Lovely and comfortable rooms. Breakfast was wonderful "
United States
douglas f
$94 nightly
The price is $106
Jan 6 - Jan 7
Total with taxes and fees
The Pepin Mansion Historic B&B

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very Good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
$169 nightly
The price is $196
Jan 6 - Jan 7
Total with taxes and fees
CozySuites at Nulu

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (44)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
$140 nightly
The price is $159
Jan 6 - Jan 7
Total with taxes and fees
stayAPT Suites Louisville North-Clarksville

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
$215 nightly
The price is $242
Jan 7 - Jan 8
Total with taxes and fees
The Reserve on Main

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
$334 nightly
The price is $352
Jan 12 - Jan 13
Total with taxes and fees
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
TWO Stunning Nulu CozySuites

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.
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Open Photo by Serendipity Trip

Top Southeastern Indiana Hotel Reviews

Find out more about Southeastern Indiana

Southeastern Indiana Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southeastern Indiana, United States of America are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southeastern Indiana 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southeastern Indiana. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southeastern Indiana, United States of America, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southeastern Indiana hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You can find a range of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a customer favorite in this city that offers a swimming pool and massage services. Another getaway that gets excellent reviews from travelers is Hyatt Regency Louisville. Designer toiletries and a swimming pool help make it their number one choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
To find a 4-star hotel in Southeastern Indiana that fits your budget, make use of Expedia's handy search filters. Browse the available options during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most wallet-friendly escape first.

  • Search for the lowest price from $106

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
Treat yourself to luxury living during your Southeastern Indiana vacation by staying at a 4-star hotel. As well as featuring upscale accommodations, these properties are typically packed with amenities like complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and unforgettable one. Round-the-clock concierge assistance, luxurious spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.