A wooden bench in a forest with a natural backdrop of trees and foliage.

Find Resorts & Hotels with Spas in Southeastern Indiana

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Check availability on Southeastern Indiana Resorts & Hotels with Spas

Tonight
Oct 5 - Oct 6
Tomorrow
Oct 6 - Oct 7
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Southeastern Indiana hotels with a spa

A restaurant with round tables, chairs, chandeliers, and a bar area.
A large hotel with a prominent 'Caesars' sign, multiple floors, and a symmetrical facade.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.
A hot tub with a pool, indoor seating area, and a view of the pool.

1. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
$89 nightly
$99 total
Nov 4 - Nov 5
Total with taxes and fees
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A modern bathroom with a shower, a sink, and a large mirror.

2. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
$173 nightly
$204 total
Oct 26 - Oct 27
Total with taxes and fees
21c Museum Hotel Louisville
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern hotel room with a large window, a sofa, a red armchair, and a small table.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

3. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
$145 nightly
$171 total
Oct 25 - Oct 26
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
A treatment room with a massage table, a desk with a computer, and a large mirror.
A luxurious bathroom with a large mirror, a bathtub, and a shower area.
A poolside area with lounge chairs and a towel with a monogram.
A golf course with a flag, a sand bunker, and a building in the background.

4. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
$155 nightly
$173 total
Oct 7 - Oct 8
Total with taxes and fees
Belterra Casino Resort
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A lobby with a marble floor, a reception desk, and a large chandelier.

5. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
$254 nightly
$299 total
Oct 30 - Oct 31
Total with taxes and fees
Omni Louisville Hotel
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A hotel room with a bed, desk, chair, and a green accent wall.
A spacious indoor area with a staircase, a vending machine, and a business center sign.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
$81 nightly
$90 total
Nov 4 - Nov 5
Total with taxes and fees
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.
A modern bathroom with a shower, a vanity with a sink, and a toilet. There are wooden shelves and a vase with flowers on the vanity.
A living room with a sofa, coffee table, and a television mounted on the wall.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
$360 nightly
$397 total
Oct 12 - Oct 13
Total with taxes and fees
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southeastern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Find out more about Southeastern Indiana

Top Southeastern Indiana attractions for a relaxing vacation

Southeastern Indiana offers a delightful blend of relaxation and adventure for travelers seeking spa hotel experiences. Begin your escape in the charming town of French Lick, home to the historic French Lick Resort, where luxurious spa services meet opulent surroundings. After a rejuvenating massage, explore the beautiful grounds, including the stunning gardens and nearby hiking trails. Just a short drive away, the Hoosier National Forest invites you to immerse yourself in nature, with miles of scenic trails perfect for hiking or biking, providing a refreshing contrast to your spa days. For a taste of local culture, visit the quaint town of Madison, known for its well-preserved 19th-century architecture and vibrant arts scene, where galleries and boutiques offer delightful shopping experiences. Additionally, the area boasts several wineries, like the nearby Lane's End Winery, where you can indulge in tastings that pair perfectly with your spa retreat. Traveling with family? The region also offers family-friendly activities like the Clifty Falls State Park, where you can enjoy picnics and gentle hikes while surrounded by stunning waterfalls. Staying in Southeastern Indiana means you can enjoy a pampering experience in luxurious accommodations, where attentive service ensures you feel valued and cared for throughout your stay.

Top Southeastern Indiana Hotel Reviews

Hyatt Select Louisville North

Hyatt Select Louisville North

8/10 Good
"This was a good place to stay over night. Phone didnt work. But the many outlets were convenient. Good location, good dark out curtains. Peaceful area."
Angel 1-night trip
Posted 1 day ago
Hyatt Select Louisville North

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