A wooden bench in a forest with a natural backdrop of trees and foliage.

Find Resorts & Hotels with Spas in Southeastern Indiana

Check availability on Southeastern Indiana Resorts & Hotels with Spas

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Southeastern Indiana hotels with a spa

1. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
$89 nightly
$99 total
Oct 26 - Oct 27
Total with taxes and fees
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

2. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
$150 nightly
$177 total
Oct 26 - Oct 27
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham

3. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
$165 nightly
$194 total
Oct 26 - Oct 27
Total with taxes and fees
21c Museum Hotel Louisville

4. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
$155 nightly
$173 total
Oct 7 - Oct 8
Total with taxes and fees
Belterra Casino Resort

5. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
$279 nightly
$329 total
Oct 18 - Oct 19
Total with taxes and fees
Omni Louisville Hotel

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
$81 nightly
$90 total
Oct 25 - Oct 26
Total with taxes and fees
Quality Inn Seymour I-65

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
$381 nightly
$421 total
Oct 19 - Oct 20
Total with taxes and fees
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southeastern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Find out more about Southeastern Indiana

Top Southeastern Indiana attractions for a relaxing vacation

Southeastern Indiana offers a delightful blend of relaxation and adventure for travelers seeking spa hotel experiences. Begin your escape in the charming town of French Lick, home to the historic French Lick Resort, where luxurious spa services meet opulent surroundings. After a rejuvenating massage, explore the beautiful grounds, including the stunning gardens and nearby hiking trails. Just a short drive away, the Hoosier National Forest invites you to immerse yourself in nature, with miles of scenic trails perfect for hiking or biking, providing a refreshing contrast to your spa days. For a taste of local culture, visit the quaint town of Madison, known for its well-preserved 19th-century architecture and vibrant arts scene, where galleries and boutiques offer delightful shopping experiences. Additionally, the area boasts several wineries, like the nearby Lane's End Winery, where you can indulge in tastings that pair perfectly with your spa retreat. Traveling with family? The region also offers family-friendly activities like the Clifty Falls State Park, where you can enjoy picnics and gentle hikes while surrounded by stunning waterfalls. Staying in Southeastern Indiana means you can enjoy a pampering experience in luxurious accommodations, where attentive service ensures you feel valued and cared for throughout your stay.

Top Southeastern Indiana Hotel Reviews

Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent
"Rated 9 out of 10 The bed was excellent to sleep in. Will stay again"
Mary 1-night trip
Posted 12 hours ago
Ramada by Wyndham Sellersburg/Louisville North
Hyatt Select Louisville North

Hyatt Select Louisville North

8/10 Good
"Breakfast is not a real buffet more like a continental, which is fine for me I just need coffee in the morning. The room was nice and clean. I was on the first floor by the elevator so it was a lot of opening of doors and noise other then that I would have given it a 5/5"
Louis 1-night trip
Posted 12 days ago
Hyatt Select Louisville North
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

10/10 Excellent
"Todo muy bello, pasamos el cumpleaños de nuestro bebé muy bien lugar muy acogedor"
Aracelys 2-night trip
Posted 2 weeks ago
Big Splash Adventure Indoor Water Park & Resort

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