
Find 4 Star Hotels in Wapello, IA from $146
- Upfront pricingOur total price for your stay includes taxes and fees
- Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
- Be pickySearch almost a million properties worldwide
Check availability on Wapello 4 Star Hotels
Our top choices for Wapello 4-star hotels

1. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
2. Evans Holly Grove Inn B&B
Evans Holly Grove Inn B&BLearn more about Wapello
Along the banks of the mighty Mississippi, this charming river town invites visitors to explore Chatauqua Park's natural beauty and peaceful surroundings. History buffs and outdoor enthusiasts can venture to nearby Lover's Leap Swinging Bridge or spend an exciting evening watching local races at CJ Speedway.

Top Wapello Hotel Reviews
Find out more about Wapello
Wapello Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Wapello, Iowa are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Wapello 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Wapello. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Wapello, Iowa, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Wapello hotels offer everything your heart desires.
Frequently asked questions
Explore a world of travel with Expedia
- Hotels in Wapello
- Cabins in Wapello
- Americinn Hotels in Oakville
- 2 Star Hotels in Wapello
- Hotels in Muscatine
- Hot Tub in Muscatine
- Bed and Breakfast in Wapello
- 5 Star Hotels in Wapello
- Hotels in Columbus Junction
- Budget in Muscatine
- Hilton Hotels in Muscatine
- Motel 6 Hotels in Muscatine
- Hotels in Mount Pleasant
- 3 Star Hotels in Wapello
- Independent Hotels in Oakville
- 4 Star Hotels in Letts
- Hotels in Grandview
- Private Vacation Homes in Muscatine
- 4 Star Hotels in Morning Sun
- Best Western Hotels in Wapello
- Hotels in Mediapolis
- Lodges in Columbus Junction
- Luxury in Wapello
- 4 Star Hotels in Grandview
- Hotels in Washington
- Apartments in Burlington
- 4 Star Hotels in West Burlington
- Hotels in West Liberty
- Wyndham Hotels in Mount Pleasant
- Casino in Burlington
- Hotels near FunCity
- 4 Star Hotels in Muscatine
- Hotels in Riverside
- 4 Star Hotels in Fruitland
- 4 Star Hotels in Columbus Junction
- 4 Star Hotels in Mediapolis
- 3 Star Hotels in Morning Sun
- 5 Star Hotels in Muscatine
- 2 Star Hotels in Grandview
- 3 Star Hotels in Burlington
- 5 Star Hotels in Burlington
- Pool in Muscatine
- Indoor Pool in Muscatine
- Pet Friendly in Muscatine
- Marriott Hotels & Resorts Hotels in Muscatine
- Romantic in Muscatine
- La Quinta Inn & Suites Hotels in Buffalo
- Waterpark in Burlington
- Drury Inn & Suites Hotels in Iowa City
- Wedding in Muscatine
- Weekend Getaways in Muscatine
- Last-Minute Hotel Deals in Mount Pleasant
- Spring Break Hotels in Iowa City
- Weekend Getaways in Coralville
- Weekend Getaways in Bettendorf
- Weekend Getaways in Burlington
- Last-Minute Hotel Deals in Fort Madison
- Weekend Getaways in North Liberty
- Last-Minute Hotel Deals in Fairfield
- Weekend Getaways in Keokuk
- Flights to Muscatine
- Flights from Chicago (ORD) to Burlington (BRL)
- Air Choice One Chicago (ORD) to Burlington (BRL) flights
- Flights to Wapello
- Flights from Denver (DEN) to Burlington (BRL)
- Delta Air Lines Minneapolis (MSP) to Cedar Rapids (CID) flights
- Flights to Mount Pleasant
- American Airlines Dallas (DFW) to Cedar Rapids (CID) flights
- Flights to Burlington
- Flights to Columbus Junction
- Flights to West Burlington
- Car rentals in Wapello
- Hertz Rental Cars in Muscatine
- Van Car Rentals in Muscatine
- Car rentals in Muscatine
- Avis Rental Cars in Muscatine
- Premium Car Rentals in Mount Pleasant
- Car rentals in Columbus Junction
- Sports Car Car Rentals in Davenport
- Car rentals in Morning Sun
- Car rentals in Mount Pleasant
- Car rentals in Burlington





