A river with a ship, surrounded by autumn foliage.

Find 5 Star Hotels in Wapello, IA from $146

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Wapello 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Wapello.
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

119 Mississippi Drive West Muscatine IA
$149 nightly
The price is $167 total per night from Nov 20 to Nov 21
$167 total
Nov 20 - Nov 21
Total with taxes and fees
Still don't see what you're looking for?
See all properties in Wapello.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Wapello

Along the banks of the mighty Mississippi, this charming river town invites visitors to explore Chatauqua Park's natural beauty and peaceful surroundings. History buffs and outdoor enthusiasts can venture to nearby Lover's Leap Swinging Bridge or spend an exciting evening watching local races at CJ Speedway.

See all hotels in Wapello
A river with a ship, surrounded by autumn foliage.

Top Wapello Hotel Reviews

Find out more about Wapello

Wapello Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Wapello are your dreams come true. From sprawling resorts to fancy hot spots, theseWapello 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Wapello, Iowa, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Wapello five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Wapello 5 star hotels.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Wapello?
The amount you pay for a 5-star hotel in Wapello can vary depending on what time of year you travel and how long you plan to be away, among other factors. Take advantage of our price per night filter and other search tools to score the best deal on a plush stay.

  • Search for the lowest price per night from $146

What makes a hotel 5 stars in Wapello?
From high-end restaurants and 24/7 fitness centers to pools and dreamy bedding, the 5-star experience in Wapello is all about comfort and indulgence. But it calls for more than just top-notch perks to earn a 5-star rating. Stays also have to deliver extraordinary guest-centric services like massage treatments, laundry and dry cleaning and concierge services.
Are there any 5-star all-inclusive resorts in Wapello?
Find a luxury stay that includes your room, meals, drinks and entertainment in Wapello with the help of our filters. Search for hotels rated 5 stars and click on the "All inclusive" filter. Have a look at what's included in the upfront price. That way, you'll be ready to maximize all the perks on offer when you arrive.

Explore a world of travel with Expedia