Muscatine Vacations from $515

Book a Hotel + Flight or Car together to unlock savings

Photo by Bill Eaker

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Muscatine Vacation

The rich history and spectacular views are just the start of the things Muscatine has to offer. Enjoy the sights and sounds of this fascinating city the way you want with a personalized Muscatine vacation package. If your trip to Muscatine includes some sightseeing, drop by famous attractions like Geneva Golf and Country Club, Muscatine Aquatic Center and Riverside Park. Don't delay your visit to this city any longer. Your perfect Muscatine vacation is a few quick clicks away with Expedia.

The Latest Muscatine vacation packages

Price found within the past 48 hours. Click for updated prices.
Hyatt House East Moline Quad Cities

Hyatt House East Moline Quad Cities

3 out of 5
per person
Aug 13 - Aug 19
found 1 day ago
Roundtrip non-stop flight included
San Jose (SJC) to Moline (MLI)
9.2/10 Wonderful! (1,000 reviews)
Love this day will definitely use this property again anytime we’re in the area

Reviewed on Jun 29, 2025

Hyatt Place East Moline Quad Cities

Hyatt Place East Moline Quad Cities

3 out of 5
per person
Aug 13 - Aug 19
found 1 day ago
Roundtrip non-stop flight included
San Jose (SJC) to Moline (MLI)
9.2/10 Wonderful! (873 reviews)
Friendly staff, exceptionally clean rooms, variety of breakfast choices. I have allergies to perfumes that many hotels use these days. I did not have that issue with this hotel. Enjoyable and very pleasant stay. Highly recommend.

Reviewed on Jul 7, 2025

Holiday Inn Express Moline - Quad Cities Area by IHG

Holiday Inn Express Moline - Quad Cities Area by IHG

2.5 out of 5
per person
Aug 13 - Aug 19
found 1 day ago
Roundtrip non-stop flight included
San Jose (SJC) to Moline (MLI)
9.4/10 Exceptional! (658 reviews)
Wonderful staff, great location for airport, spacious rooms

Reviewed on Jul 9, 2025

Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

3.5 out of 5
per person
Aug 13 - Aug 19
found 1 day ago
Roundtrip non-stop flight included
San Jose (SJC) to Moline (MLI)
9/10 Wonderful! (1,140 reviews)
Clean and good location.

Reviewed on Jul 9, 2025

Comfort Inn & Suites East Moline near I-80

Comfort Inn & Suites East Moline near I-80

2.5 out of 5
per person
Aug 13 - Aug 19
found 1 day ago
Roundtrip non-stop flight included
San Jose (SJC) to Moline (MLI)
8/10 Very Good! (357 reviews)
Great breakfast. I attended during the John Deere Classic PGA tournament, and the location was perfect! I would definitely stay again. Price was good also. Thanks!

Reviewed on Jul 5, 2025

Don't see what you're looking for?
See all available trips from Columbus to Muscatine
View all trips

Discover the most popular places to visit in Muscatine

Riverside Park

4/5(31 reviews)

Explore the great outdoors at Riverside Park, a lovely green space in Muscatine. Discover the area's entertainment venues and churches.

Riverside Park

Muscatine Art Center

3/5(1 review)

You can spend time exploring the galleries in Muscatine Art Center in Muscatine. Experience the area's entertainment venues and theater scene.

Muscatine Art Center

Geneva Golf and Country Club

Enjoy a round of golf in Muscatine at Geneva Golf and Country Club. Amble around the area's riverfront or experience its entertainment venues.

Geneva Golf and Country Club

Muscatine Hotel Deals

Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $96 total per night from Jul 16 to Jul 17
$96 total
Jul 16 - Jul 17
Total includes taxes and fees
8.4/10 Very Good! (455 reviews)
"Staff was prompt and courteous - they paid good attention to the breakfast area and kept things stocked. Hotel was clean and well kept. Pool area was rather small and very full with lots of kids. Overall, good stay!"

Reviewed on May 19, 2025

Best Western Muscatine / Pearl City Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Jul 20 to Jul 21
$90 total
Jul 20 - Jul 21
Total includes taxes and fees
7.4/10 Good! (383 reviews)
"Everything was good, the only thing that didn't work was the hot tub. It had no hot water and the timer was to short hopefully thier fixed by the time we go on our next family trip."

Reviewed on Jul 5, 2025

AmericInn by Wyndham Muscatine
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Jul 13 to Jul 14
$122 total
Jul 13 - Jul 14
Total includes taxes and fees
8.4/10 Very Good! (428 reviews)
"The staff were very friendly . The breakfast was better than most and the room was comfortable."

Reviewed on Jul 6, 2025

Hampton Inn Muscatine
See all 294 properties in Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Muscatine Vacation Packages

Muscatine Essential Information

Language
English
Currency
U.S dollars
Population
24,000
Max Temp Winter
30ºF
Max Temp Summer
80ºF
Top Sights
Wildcat Den State Park, Fairport State Recreation Area and Riverside Park

More vacations you might like

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Frequently asked questions

How much does a Muscatine vacation package cost?
Offering great value package deals from $515 on Expedia, you'll be thrilled with how little a vacation to Muscatine costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Muscatine?
January, February and August are great times to look for cheap Muscatine vacation packages. Traveling in less busy months means you'll typically find better prices on flights and accommodations.
How many days is enough for Muscatine?
The ideal length of your Muscatine vacation depends on what you'd like to see. Generally, a few days to a week will give you time to visit all the major attractions and discover some hidden gems along the way.
Is it worth booking a vacation package to Muscatine?
Whether you'd like to explore major attractions like Muscatine Aquatic Center and Riverside Park on your Muscatine vacation, or coming for its excellent history, walking trails and family-friendly attractions, there's something for everyone here. With so many things to do, you'll soon discover why so many families think Muscatine is a good vacation destination.
How to find the best Muscatine package deals?
Start your search for a Muscatine package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Popular locations" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the ideal Muscatine package deal straight away, simply switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Muscatine escape underway.
Is it cheaper to book a Muscatine vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging stays and flights individually. Better still, you can customize your Muscatine trip to fit your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Muscatine?
If you've got your Muscatine vacation dates confirmed, book as early as you can to score some terrific deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are ideal for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Muscatine vacation packages?
If you're anything like us, you love traveling the world but don't love the price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your Muscatine trip over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.