Title: The Best 5 Star Hotels in Defiance, OH from $139 | Expedia.com [Defiance Travel Guide](https://expedia.com/Defiance.dx6059291)[Hotels in Defiance](https://expedia.com/Defiance-Hotels.d6059291.Travel-Guide-Hotels)[Vacation Rentals in Defiance](https://expedia.com/Defiance-Vacation-Rentals.d6059291.Travel-Guide-VacationRentals)[Flights to Defiance](https://expedia.com/Cheap-Flights-To-Defiance.d6059291.Travel-Guide-Flights)[Car Rentals in Defiance](https://expedia.com/Car-Rentals-In-Defiance.d6059291.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.com/Defiance.d6059291.Destination-Travel-Guides) ![Aerial View of Historic Courthouse and River in Small Town Ohio](https://images.trvl-media.com/place/6059291/3b2bf203-f05d-4887-b02b-2f0f9cf0e794.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6059291/3b2bf203-f05d-4887-b02b-2f0f9cf0e794.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Defiance 5 Star Hotels Tonight [Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=6059291&startDate=2026-03-10&endDate=2026-03-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.com/Hotel-Search?regionId=6059291&startDate=2026-03-11&endDate=2026-03-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6059291&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6059291&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Defiance 5-star hotels ![Front of property](https://images.trvl-media.com/lodging/125000000/124820000/124810400/124810313/7a1df1fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cabin, Lake View | Living area](https://images.trvl-media.com/lodging/125000000/124820000/124810400/124810313/bb1bd432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/125000000/124820000/124810400/124810313/57ea02b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/125000000/124820000/124810400/124810313/03e565c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fox Lakeview Lodge [](https://www.expedia.com/Angola-Hotels-Fox-Lakeview-Lodge.h124810313.Hotel-Information) Angola 10/10 Exceptional (2 reviews) "Very clean. Very pretty place to stay and can’t wait come back this summer with the kids and do activities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) London $298 nightly $334 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Angola-Hotels-Fox-Lakeview-Lodge.h124810313.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Defiance-Hotels.s50-0-d6059291.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Defiance-Hotels.s50-0-d6059291.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Defiance. ![Renaissance Toledo Downtown Hotel](https://images.trvl-media.com/lodging/1000000/90000/82800/82746/8088f6b5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Renaissance Toledo Downtown Hotel 444 N Summit Street Toledo OH $118 nightly $139 total Mar 29 - Mar 30 Total with taxes and fees 8.6/10 Excellent! (1,011 reviews) [](https://expedia.com/Toledo-Hotels-Renaissance-Toledo-Downtown-Hotel.h82746.Hotel-Information) ![Between Restaurant & Brewery! Chic Perrysburg Apt](https://images.trvl-media.com/lodging/123000000/122570000/122561400/122561313/4f5a2b2e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Between Restaurant & Brewery! Chic Perrysburg Apt Perrysburg OH [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F24%2F2026&endDate=3%2F25%2F2026&selected=122561313&PinnedHotelID=122561313&HadPinnedHotel=true®ionId=6059291) [](https://expedia.com/Toledo-Hotels-Between-Restaurant-Brewery-Chic-Perrysburg-Apt.h122561313.Hotel-Information) Still don't see what you're looking for? [See all properties in Defiance.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=6059291&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Defiance and related destinations - Defiance - Mayfield - Kokomo - Greenville - Luling Stroll along the Maumee River at Pontiac Park, where locals gather for picnics and kayaking adventures. History buffs can explore Fort Defiance's reconstructed blockhouses or catch a show at the restored 1920s Valentine Theatre. [See all hotels in Defiance](https://www.expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25&adults=2®ionId=6059291) ![Aerial View of Historic Courthouse and River in Small Town Ohio](https://images.trvl-media.com/place/6059291/3b2bf203-f05d-4887-b02b-2f0f9cf0e794.jpg?impolicy=fcrop&w=900&h=505&p=1&q=high) ## Top Defiance Hotel Reviews ## Find out more about Defiance You enjoy the finer things in life, both at home and on vacation. Why not request the best of accommodations during your excursion to Defiance? There's no reason to delay a getaway to Defiance any longer. You'll join the multitudes of vacationers who have made Defiance so fashionable recently. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Defiance and get ready to enjoy the getaway of a lifetime. ### Get a Great Deal on 5-Star Hotels in Defiance Don't be afraid to live the high life while you're on vacation, along with the best conditions. Exceptional service, delicious meals, and attentive guest service are all at your fingertips. You're sure to find exactly the accommodation you need. We should also mention, the hotels in this area receive noteworthy marks for customer satisfaction, so you know you'll be well cared for during your getaway. What kind of amenities will make your stay a wonderful one? A concierge to help you make reservations at that outstanding restaurant? A deep-tissue massage to help your cares fall away? Comfortable beds, lip-smacking main courses, and even spectacular views...these hotels will astonish you. Want to see for yourself? Plenty of visitors recommend this location. But you aren't going to spend your entire vacation in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Defiance are waiting for you to rest up after a busy day. ### Your Getaway Starts Today The results are in, and Defiance 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Decide on one of Expedia's Defiance 5-star hotels today and settle down in luxe surroundings at your convenience. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Defiance? > - Search for the lowest price per night from $139 ### What makes a hotel 5 stars in Defiance? ### Are there any 5-star all-inclusive resorts in Defiance? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Okolona Hotels ](https://www.expedia.com/Okolona-Hotels.d3000453422.Travel-Guide-Hotels) - [Evansport Hotels ](https://www.expedia.com/Evansport-Hotels.d3000351943.Travel-Guide-Hotels) - [Ney Hotels ](https://www.expedia.com/Ney-Hotels.d3000352097.Travel-Guide-Hotels) - [Holgate Hotels ](https://www.expedia.com/Holgate-Hotels.d3000351985.Travel-Guide-Hotels) - [Continental Hotels ](https://www.expedia.com/Continental-Hotels.d553248634983448708.Travel-Guide-Hotels) - [5 Star Hotels in Napoleon ](https://www.expedia.com/5Star-Napoleon-Hotels.s50-0-d9010.Travel-Guide-Filter-Hotels) - 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