Main Street Hyannis Tours

Main Street Hyannis which includes street scenes as well as a couple
Main Street Hyannis showing signage
Main Street Hyannis featuring street scenes as well as a couple
Main Street Hyannis
Main Street Hyannis showing signage

Plan a trip to see Main Street Hyannis

Price found within the past 48 hours. Click for updated prices.
Chapter House

Chapter House

3.5 out of 5
per person
Aug 4 - Aug 7
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Hyannis (HYA)
9.4/10 Exceptional! (149 reviews)
The people were wonderful, accommodating, and just plain nice. I would recommend some kind of anti slip item for the shower as it is very smooth and slick. Otherwise, everything was excellent.

Reviewed on Jun 22, 2025

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

3 out of 5
per person
Aug 13 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Hyannis (HYA)
9.4/10 Exceptional! (1,001 reviews)
The property was well-maintained and nicely decorated. We spent a hot afternoon in the pool and enjoyed the harbor view. The room we stayed in was a double and was comfortable. There was one real problem, however, in that the bathroom had a very strong mildew smell. The odor was so strong that we had to keep the door closed and spend as little time in it as possible. We think the shower curtain was the source; we saw some mold and mildew spots on the bottom of it.

Reviewed on Jun 25, 2025

Inn on Main

Inn on Main

3.5 out of 5
per person
Aug 4 - Aug 7
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Hyannis (HYA)
10/10 Exceptional! (68 reviews)
Terrific B&B on Cape Cod - super dog friendly and very hospitable! Excellent breakfasts, charming space, and wonderful hosts. It’s a very convenient mid-Cape location, you will not regret booking with them.

Reviewed on May 10, 2025

Popular places to visit

John F. Kennedy Hyannis Museum showing a statue or sculpture

John F. Kennedy Hyannis Museum

4.5/5(137 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

John F. Kennedy Hyannis Museum
Hyannis

Cape Cod Maritime Museum

Learn about boats, boatbuilding and more at this beloved Hyannis museum dedicated to inspiring and educating visitors about maritime topics.

Cape Cod Maritime Museum
Hyannis

St. Francis Xavier Church

4.5/5(8 reviews)

Learn about the local history of Hyannis with a stop at St. Francis Xavier Church. Amble around this family-friendly area's beautiful beaches and enjoy its seafood restaurants.

St. Francis Xavier Church
Hyannis Harbor which includes a sunset and a bay or harbor as well as a small group of people

Hyannis Harbor

4.5/5(591 reviews)

See the Cape Cod peninsula from a different perspective by riding a boat out of this picturesque harbor or wandering along its docks and jetties.

Hyannis Harbor
John F. Kennedy Memorial

John F. Kennedy Memorial

4.5/5(24 reviews)

Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.

John F. Kennedy Memorial

Hyannis Armory

Learn about the local history of Hyannis when you take a trip to Hyannis Armory. Wander the waterfront and beautiful beaches in the area.

Hyannis Armory

Best Lodging Options Near Main Street Hyannis

Hyannis Inn
Hyannis Inn
2 out of 5
473 MAIN ST, Hyannis, MA
Hyannis Inn
Hyannis Travel Inn
Hyannis Travel Inn
2.5 out of 5
18 North St, Hyannis, MA
Hyannis Travel Inn
Hyannis Plaza Hotel
Hyannis Plaza Hotel
2.5 out of 5
662 Main Street, Hyannis, MA
Hyannis Plaza Hotel
Cape Cod Inn
Cape Cod Inn
2 out of 5
447 Main St, Hyannis, MA
Cape Cod Inn
Americas Best Value Inn & Suites Hyannis Cape Cod
Americas Best Value Inn & Suites Hyannis Cape Cod
2 out of 5
206 Main St, Hyannis, MA
Americas Best Value Inn & Suites Hyannis Cape Cod
Hyannis Harbor Hotel
Hyannis Harbor Hotel
3.5 out of 5
213 Ocean St, Hyannis, MA
Hyannis Harbor Hotel
Comfort Inn Hyannis - Cape Cod
Comfort Inn Hyannis - Cape Cod
2.5 out of 5
259 Main Street, Hyannis, MA
Comfort Inn Hyannis - Cape Cod
Cape Sands Inn
Cape Sands Inn
2.5 out of 5
149 Main St - RT 28, West Yarmouth, MA
Cape Sands Inn
Heritage House Inn on Cape Cod
Heritage House Inn on Cape Cod
2.5 out of 5
540 Old Colony Rd, Hyannis, MA
Heritage House Inn on Cape Cod
See all 3,718 properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.