
$67 Car Rental De Soto, MO
Search and Compare from Car Companies in De Soto
Featured car rental suppliers
Compare from agencies
Change your mind: penalty-free cancellation on many/select car rentals
Treat yourself: One Key members save 10% or more on over 1 million car rentals
Shop Smart: Compare car suppliers and package your flight, hotel, and car to save
Top Car Deals in De Soto
* Price found within the past 6 days. Click for updated prices.
Economy


$67
Special


$82
Compact


$78
Fullsize


$91
Premium


$96
Standard SUV


$87
Midsize


$87
Fullsize Elite Pickup Regular Cab


$119
Midsize Elite


$115
Standard Elite SportsCar


$120
Mini Van


$138
Luxury


$145
Luxury Elite


$156
Premium Elite Crossover


$167
Frequently asked questions
Car Rental Information
SUV, Full Size, Economy | |
$67 | |
$78 | |
$82 | |
Airport Transportation | |
Airport Car Rentals |
Finding the cheapest car rentals in De Soto
Using our Search Wizard
If the deals that are available on our page do not suit your needs, then enter De Soto into the search wizard at the top of the page. We will compare all the best deals available for your car rental in De Soto and provide you with a list of the cheapest options, with no added fees.
Renting a car in De Soto
Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in De Soto. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.
Expected prices in De Soto
Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $67.
Flexibility & Cancellation
Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.
We all love being rewarded
One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.
Car classes available from Expedia in 2025
The classes of vehicles available will change depending on your chosen location.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Hematite Hotels
- Condo Resorts in Hematite
- Hillsboro Hotels
- Cabin Rentals in Hillsboro
- Drury Inn & Suites Hotels in Hillsboro
- 3 Star Hotels in Hillsboro
- Vacation Homes in Hillsboro
- Condo Rentals in Hillsboro
- Apartments in Hillsboro
- Motels in Hillsboro
- Villas in Hillsboro
- Hotels near Washington State Park
- Tiff Hotels
- B&B in Tiff
- Cabin Rentals in Tiff
- Lodges in Tiff
- 5 Star Hotels in Tiff
- Festus Hotels
- Drury Inn & Suites Hotels in Festus
- Cheap Hotels in Festus
- Pet-friendly Hotels in Festus
- Motels in Festus
- Hotels with an Indoor Pool in Festus
- Hotels with Restaurants in Festus
- Hotels with a Pool in Festus
- B&B in Festus
- Hotels with smoking rooms in Festus
- Hotel Wedding Venues Hotels in Festus
- Hotels with Connecting Rooms in Festus
- Hotels with Bars in Festus
- Villas in Festus
- Hotels with an Outdoor Pool in Festus
- Gay friendly Hotels in Festus
- Cabin Rentals in Festus
- Vacation Homes in Festus
- 3 Star Hotels in Festus
- Hotels with Free Breakfast in Festus
- Luxury Hotels in Festus
- Hotels with Air Conditioning in Festus
- Hotels with Laundry Facilities in Festus
- 4 Star Hotels in Festus
- Wyndham Hotels in Festus
- Hotels & Resorts for Couples in Festus
- Resorts & Hotels with Spas in Festus
- 5 Star Hotels in Festus
- Best Western Hotels in Festus
- Condo Rentals in Festus
- Family Hotels in Festus
- RV Parks in Festus
- Hotels near Villa Antonio Winery
- Hotels near Sandy Creek Covered Bridge State Historic Site
- Crystal City Hotels
- Valles Mines Hotels
- Hotels near St. Francois State Park
- Dittmer Hotels
- Herculaneum Hotels
- Vacation Homes in Dittmer
- 5 Star Hotels in Dittmer
- Motels in Dittmer
- 3 Star Hotels in Dittmer
- Cabin Rentals in Dittmer
- Car rentals near Olympian Village
- Car rentals near Hematite
- Car rentals near Hillsboro
- Car rentals near Mapaville
- Car rentals near Tiff
- Car rentals near Festus
- Economy Car Rentals in Tiff
- Sixt Rental Cars in Tiff
- Europcar Rental Cars in Tiff
- Enterprise Rental Cars in Festus
- Van Car Rentals in Festus
- Hertz Rental Cars in Festus
- Minivan Car Rentals in Festus
- Car rentals near Morse Mill
- Car rentals near Horine
- Car rentals near Crystal City
- Car rentals near Valles Mines
- Car rentals near St. Francois State Park
- Car rentals near Herculaneum
- Car rentals near Dittmer