De Soto Vacation Rentals

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Our top choices for De Soto vacation rentals

82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin
De Soto
10.0 out of 10, Exceptional, (41 reviews)
"The cabin was wonderful with many extras like snacks and coffee."
United States
Janna B.
$257 nightly
The price is $266
Jan 25 - Jan 26
Total with taxes and fees
82 Acre Hobby Farm with Lincoln Log Cabin

Hagood farms and trails

Hagood farms and trails
Sullivan
9.6 out of 10, Exceptional, (7 reviews)
"Nice area, the fishing was good and the place was very clean. I would stay here again and again"
United States
Brenda
$110 nightly
The price is $110
Jan 24 - Jan 25
Total with taxes and fees
Hagood farms and trails

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (48 reviews)
"I had a great time with my mom there!"
United States
Lily
$129 nightly
The price is $139
Jan 26 - Jan 27
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
$139 nightly
The price is $147
Jan 24 - Jan 25
Total with taxes and fees
Tiny Houses of French Village

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (8 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
$223 nightly
The price is $234
Jan 24 - Jan 25
Total with taxes and fees
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (13 reviews)
"The home was very clean and well cared for. It was fully stocked with all the necessities. The bed was comfortable. I would definitely stay here again. "
United States
Billie N.
$223 nightly
The price is $234
Jan 24 - Jan 25
Total with taxes and fees
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Pet-Friendly Bluff Cabin by Sunnen Lake

Pet-Friendly Bluff Cabin by Sunnen Lake
Potosi
10.0 out of 10, Exceptional, (1 review)
"Easy to book; friendly staff; keycard entry; clean cabin and porch; quiet; grounds well kept; kitchen had all needed items ( maybe add a toaster) ; screened in porch ; air and fan. Good cell reception , pretty lake ; good location "
United States
David
$139 nightly
The price is $139
Jan 25 - Jan 26
Total with taxes and fees
Pet-Friendly Bluff Cabin by Sunnen Lake

Peter Ray House

Peter Ray House
Maeystown
10.0 out of 10, Exceptional, (71 reviews)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
$211 nightly
The price is $224
Jan 24 - Jan 25
Total with taxes and fees
Peter Ray House

Cute town house with fenced backyard

Cute town house with fenced backyard
Barnhart
9.6 out of 10, Exceptional, (17 reviews)
"It was a great place to stay for our needs we had our little dog with us as was there for weekend, it had a nice fenced back yard we could let her just go out didn't have to have her on leash. Was very nice inside clean well kept, beds were surprising comfortable. The host stayed in contact and answered a lot questions before we arrived which put me a ease for our trip. High recommand this place if needing to stay in the area. "
United States
Terry
$238 nightly
The price is $252
Jan 28 - Jan 29
Total with taxes and fees
Cute town house with fenced backyard

Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Farmington
10.0 out of 10, Exceptional, (22 reviews)
"Everything about this property was amazing and perfect for our family! They were so helpful with everything and our kids loved it here!!"
United States
Heaven B.
$209 nightly
The price is $221
Feb 8 - Feb 9
Total with taxes and fees
Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Parkside B&B

Parkside B&B
Farmington
10.0 out of 10, Exceptional, (1 review)
"Great property, quiet, clean, home away from home. Thank you"
United States
ana G.
$234 nightly
The price is $234
Feb 2 - Feb 3
Total with taxes and fees
Parkside B&B

In the Country a Beautiful 2-bedroom house with its own private lake

In the Country a Beautiful 2-bedroom house with its own private lake
Waterloo
10.0 out of 10, Exceptional, (8 reviews)
"Do yourself a favor and book this property. We have booked many properties all over Illinois and Missouri and this place just jumped to the top of our list. The property is so relaxing in countless ways. Very secluded, yet restaurants and everything you need are just 15 minutes away in Waterloo."
United States
Jeff
$238 nightly
The price is $252
Jan 25 - Jan 26
Total with taxes and fees
In the Country a Beautiful 2-bedroom house with its own private lake

Miette Suite at Baetje Farms

Miette Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful space. Had a lovely time. Don’t forget to feed the goats."
United States
John P.
$145 nightly
The price is $145
Jan 25 - Jan 26
Total with taxes and fees
Miette Suite at Baetje Farms

Adorable small house - quiet & safe - 2 BR 1 Bath

Adorable small house - quiet & safe - 2 BR 1 Bath
Imperial
9.4 out of 10, Exceptional, (13 reviews)
"Great place for a short get away"
United States
andytrower U.
$181 nightly
The price is $191
Jan 25 - Jan 26
Total with taxes and fees
Adorable small house - quiet & safe - 2 BR 1 Bath

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.
New Offenburg
10.0 out of 10, Exceptional, (7 reviews)
"Relaxing setting between Farmington and St Genevieve. Both towns are rich in history and have small town charm. "
United States
Tim M.
$269 nightly
The price is $281
Jan 28 - Jan 29
Total with taxes and fees
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

Vallee Suite at Baetje Farms

Vallee Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (4 reviews)
"It was beautiful, quite and everything we expected!! Thanks for a great stay!!"
United States
Heather
$140 nightly
The price is $140
Jan 25 - Jan 26
Total with taxes and fees
Vallee Suite at Baetje Farms

Cute ranch house -quiet & safe -3 BR 1 Bath

Cute ranch house -quiet & safe -3 BR 1 Bath
Imperial
9.8 out of 10, Exceptional, (22 reviews)
"The home was very clean, beds were comfortable, and overall a very nice stay."
United States
Michaela H.
$203 nightly
The price is $215
Jan 25 - Jan 26
Total with taxes and fees
Cute ranch house -quiet & safe -3 BR 1 Bath

Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (24 reviews)
"Wife just loved the place"
United States
Stanley H.
$145 nightly
The price is $152
Jan 24 - Jan 25
Total with taxes and fees
Clifford's Country Cottage

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill
Byrnes Mill
10.0 out of 10, Exceptional, (12 reviews)
"Great place to stay. Huge fenced in backyard for dogs to run around. Host was real helpful with any questions we had"
United States
Michael A.
$286 nightly
The price is $298
Feb 4 - Feb 5
Total with taxes and fees
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

3-bedroom house in nice downtown Farmington with AC, WiFi, nice outdoor spaces!

3-bedroom house in nice downtown Farmington with AC, WiFi, nice outdoor spaces!
Farmington
10.0 out of 10, Exceptional, (7 reviews)
"We loved the home. So welcoming, nicely decorated, comfortable, easy check-in checkout. We will find a rrason to come back for a longer stay."
United States
Rhonda S.
$389 nightly
The price is $436
Jan 30 - Jan 31
Total with taxes and fees
3-bedroom house in nice downtown Farmington with AC, WiFi, nice outdoor spaces!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $92 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to the most popular attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay. De Soto is known for its restaurants.

What are some of the best vacation home rentals that De Soto has to offer?

Clifford's Country Cottage: This vacation home near De Soto is located in a rural location and has a fireplace, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What’s there to see and do in De Soto?

Sunrise Lake Beach and Big River are a couple of lovely local spots to get outside and enjoy nature. While here, Washington State Park and Big Lake are other places worth a visit.

What’s a vacation rental in De Soto like?

Vacation rentals are private properties you can stay in for several days or longer in De Soto. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you want. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family getaway.