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De Soto Vacation Rentals

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Vacation Rentals in De Soto

Cabin in De Soto

10.0 out of 10, Exceptional, (41)
"Had a great stay enjoyed the beds, porches and the chickens. Great mornings listening to the birds. "
United States
posata c.
$257 nightly
The price is $266
Dec 10 - Dec 11
Total with taxes and fees
82 Acre Hobby Farm with Lincoln Log Cabin

Mobile Home in Bloomsdale

10.0 out of 10, Exceptional, (4)
"It was beautiful, quite and everything we expected!! Thanks for a great stay!!"
United States
Heather
$140 nightly
The price is $140
Dec 10 - Dec 11
Total with taxes and fees
Vallee Suite at Baetje Farms

Mobile Home in Bloomsdale

10.0 out of 10, Exceptional, (2)
"It was super cozy and relaxed, the kind of place that makes you want to slow down and just hang out. Really warm vibe, almost like a little hidden getaway"
United States
Eric C.
$145 nightly
The price is $145
Dec 10 - Dec 11
Total with taxes and fees
Coeur de la Crème Suite at Baetje Farms

Camping in Sullivan

9.6 out of 10, Exceptional, (7)
"I cannot say enough good things about this property. If quiet and beauty is what you are looking for it's here. Its about 15-20 minutes either way. There is a road next to it but we didn't see a lot of traffic. We unfortunately got rained out and had to leave early so didn't get to emjoy it more. Heidi waa very helpful and understanding about this and even though she was at a family function she took the time to answer my questions. Very sweet and friendly lady. We are already planning a trip...
United States
kelly
$110 nightly
The price is $110
Dec 10 - Dec 11
Total with taxes and fees
Hagood farms and trails

Apartment in Bonne Terre

9.2 out of 10, Wonderful, (17)
"Really nice and enjoyable....would stay again"
United States
mark n.
$160 nightly
The price is $164
Dec 13 - Dec 14
Total with taxes and fees
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

Cabin in Leadwood

9.4 out of 10, Exceptional, (6)
"Same as always everything was great!"
United States
Rob M.
$145 nightly
The price is $148
Dec 19 - Dec 20
Total with taxes and fees
Cabin getaway with hot tub

Cabin in Leadwood

9.6 out of 10, Exceptional, (39)
"Just what we expected. Very quiet and secluded. Close to towns. "
United States
Cheyenne F.
$145 nightly
The price is $156
Dec 11 - Dec 12
Total with taxes and fees
Cabin 1 at the Pallet Factory

Vacation Home in Farmington

8.6 out of 10, Excellent, (4)
"Great place. "
United States
Diana
$138 nightly
The price is $138
Dec 10 - Dec 11
Total with taxes and fees
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Vacation Home in Leadwood

8.6 out of 10, Excellent, (9)
"Was pretty clean and overall enjoyed our stay"
United States
Nicole V.
$185 nightly
The price is $185
Dec 14 - Dec 15
Total with taxes and fees
The Shack- 3 bedroom finished house

Vacation Home in French Village

2.5 star property
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
$304 nightly
The price is $323
Dec 10 - Dec 11
Total with taxes and fees
Tiny Houses of French Village

Vacation Home in Farmington

10.0 out of 10, Exceptional, (6)
"Absolutely LOVED it here! Hope to return in 2026. Karli made my first Vrbo experience just plain splendid!"
United States
Tru L.
$177 nightly
The price is $183
Dec 10 - Dec 11
Total with taxes and fees
Cozy 1-bedroom house with AC and WiFi in charming Farmington

Vacation Home in Imperial

10.0 out of 10, Exceptional, (4)
"We had a nice stay in the area, and we were looking for a reasonably priced lodging for the whole family. There are a couple inflatable mattresses included in case additional beds are required. The full kitchen was appreciated, as was the comfortable couch. Solid proximity to other businesses and towns. The property is a little tricky to spot from afar off the side of the road, but it's easy to see once you're near it (Google maps is helpful). Overall, a good stay & I would stay here again!"
United States
Zach L.
$74 nightly
The price is $75
Dec 15 - Dec 16
Total with taxes and fees
Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Vacation Home in Farmington

9.6 out of 10, Exceptional, (29)
"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"
United States
Jody C.
$235 nightly
The price is $245
Dec 10 - Dec 11
Total with taxes and fees
Cozy Three bedroom home in Central Farmington

Vacation Home in Leadwood

9.8 out of 10, Exceptional, (14)
"Well taken care of, nice amenities, comfortable."
United States
Daniel K.
$195 nightly
The price is $195
Dec 22 - Dec 23
Total with taxes and fees
In-law Suite

Vacation Home in Farmington

2.0 star property
10.0 out of 10, Exceptional, (11)
"Great place and very comfortable! Hosts were super attentive when our door code didn’t work and got us sorted out right away. "
United States
Kyser B.
$219 nightly
The price is $230
Dec 10 - Dec 11
Total with taxes and fees
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Vacation Home in Park Hills

8.8 out of 10, Excellent, (6)
"Stayed here as it was close to our newly purchased home. The home was comfortable and quiet. "
United States
Greg S.
$209 nightly
The price is $209
Dec 14 - Dec 15
Total with taxes and fees
Modern Newly built 2-bedroom house minutes from downtown Park Hills

Vacation Home in Imperial

9.4 out of 10, Exceptional, (13)
"Great place for a short get away"
United States
andytrower U.
$192 nightly
The price is $203
Dec 10 - Dec 11
Total with taxes and fees
Adorable small house - quiet & safe - 2 BR 1 Bath

Vacation Home in Farmington

2.0 star property
10.0 out of 10, Exceptional, (8)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
$216 nightly
The price is $227
Jan 4 - Jan 5, 2026
Total with taxes and fees
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

Vacation Home in Maeystown

10.0 out of 10, Exceptional, (70)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
$211 nightly
The price is $224
Dec 10 - Dec 11
Total with taxes and fees
Peter Ray House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $110 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to the most popular attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay. De Soto is known for its restaurants.

What are some of the best vacation home rentals that De Soto has to offer?

In the Country a Beautiful 2-bedroom house with its own private lake: Located near De Soto, this vacation home rental has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in De Soto?

Sunrise Lake Beach and Big River are a couple of lovely local spots to get outside and enjoy nature. While here, Washington State Park and Big Lake are other places worth a visit.

What’s a vacation rental in De Soto like?

Vacation rentals are private properties you can stay in for several days or longer in De Soto. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you want. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family getaway.