$85 Cheap Flights from Detroit (DTW) to St. Louis (STL)

View $85 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Detroit to St. Louis (DTW-STL)

Prices were available within the past 7 days and start at $85 for one-way flights and $164 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, Oct 24 - Tue, Oct 28
DTW
Detroit
STL
St. Louis
$164 Roundtrip, found 1 day ago
$164
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Oct 24 from Detroit to St. Louis, returning Tue, Oct 28, priced at $164 found 1 day ago
Frontier Airlines
Sun, Nov 2 - Tue, Nov 4
DTW
Detroit
STL
St. Louis
$168 Roundtrip, found 3 days ago
$168
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Nov 2 from Detroit to St. Louis, returning Tue, Nov 4, priced at $168 found 3 days ago
Frontier Airlines
Fri, Nov 7 - Thu, Nov 13
DTW
Detroit
STL
St. Louis
$170 Roundtrip, found 6 hours ago
$170
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Fri, Nov 7 from Detroit to St. Louis, returning Thu, Nov 13, priced at $170 found 6 hours ago
United
Thu, Nov 13 - Sat, Nov 15
DTW
Detroit
STL
St. Louis
$174 Roundtrip, found 2 days ago
$174
Roundtrip
found 2 days ago
Select United flight, departing Thu, Nov 13 from Detroit to St. Louis, returning Sat, Nov 15, priced at $174 found 2 days ago
United
Tue, Oct 28 - Wed, Oct 29
DTW
Detroit
STL
St. Louis
$179 Roundtrip, found 2 days ago
$179
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 28 from Detroit to St. Louis, returning Wed, Oct 29, priced at $179 found 2 days ago
United
Wed, Oct 29 - Thu, Oct 30
DTW
Detroit
STL
St. Louis
$181 Roundtrip, found 2 hours ago
$181
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Oct 29 from Detroit to St. Louis, returning Thu, Oct 30, priced at $181 found 2 hours ago
Frontier Airlines
Sun, Nov 16 - Wed, Nov 19
DTW
Detroit
STL
St. Louis
$182 Roundtrip, found 3 days ago
$182
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Nov 16 from Detroit to St. Louis, returning Wed, Nov 19, priced at $182 found 3 days ago
American Airlines
Sun, Dec 14 - Mon, Dec 15
DTW
Detroit
STL
St. Louis
$183 Roundtrip, found 1 day ago
$183
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Dec 14 from Detroit to St. Louis, returning Mon, Dec 15, priced at $183 found 1 day ago
Delta
Thu, Jan 1 - Tue, Jan 6
DTW
Detroit
STL
St. Louis
$196 Roundtrip, found 3 days ago
$196
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jan 1 from Detroit to St. Louis, returning Tue, Jan 6, priced at $196 found 3 days ago
Southwest Airlines
Tue, Oct 28 - Wed, Oct 29
DTW
Detroit
STL
St. Louis
$203 Roundtrip, found 3 days ago
$203
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Detroit to St. Louis, returning Wed, Oct 29, priced at $203 found 3 days ago

Find the cheapest month to fly from Detroit (DTW) to St. Louis (STL)

September is typically the cheapest month to fly

From $60 - $327 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $325
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $325

Frequently asked questions

How much does a flight from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL) cost?
Secure a cheap one-way flight from $85 or cheap return flight from $164 from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
October is the most affordable month to fly from DTW to STL. Avoiding peak travel times is often the key to finding better deals on flights.
Which airlines fly direct from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
You can fly nonstop from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL) on a Delta Air Lines flight.
What is the cheapest airline that flies from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
While prices can vary depending on your travel dates, low-cost airlines like WestJet and Southwest Airlines are often the cheapest options for flights between Detroit Metropolitan Wayne County Airport (DTW) and Lambert-St. Louis Intl. Airport (STL). Use Expedia's filter tool to compare carriers and find the one that offers the lowest fare for your DTW to STL flight.
How many flights per day from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
When taking off from Detroit Metropolitan Wayne County Airport (DTW), you can take your pick from an average of 4 daily nonstop flights to Lambert-St. Louis Intl. Airport (STL).
What are the most popular departure times for flights from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
More passengers fly between DTW and STL at 8 AM than at any other point in the day. Looking to skip the crowds? Travel outside of rush hours and you're likely to save on your ticket as well.
What day of the week has the most flights from DTW to STL?
If you fly on a Wednesday, you'll get the greatest range of options for flights from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
The earliest flight departing from Detroit Metropolitan Wayne County Airport (DTW) is at around 8:40AM UTC-5. Hop on this flight and you'll land at Lambert-St. Louis Intl. Airport (STL) at approximately 9:36AM UTC-6. The total travel time is 1h 56m.
How long does it take to fly from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
The average flight time from DTW to STL is 1 hour and 50 minutes, covering a distance of 440 mi.
What airline has the least delays from DTW to STL?
With 100% of flights typically arriving on time, Aeromexico has the best on-time performance for nonstop flights from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL). To check your flight status and get notified about any changes, use the Expedia App.
What is the best time to fly from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
To arrive at Lambert-St. Louis Intl. Airport (STL) on schedule, pick a flight that leaves Detroit Metropolitan Wayne County Airport (DTW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from Detroit Metropolitan Wayne County Airport (DTW)?
Check out your flight options from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL). This is the only airport in St. Louis you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until right before your break to book a flight from DTW to STL generally means paying more. While you may find some last-minute offers, they aren't always guaranteed. Keep your travel plans flexible for the best chance of snagging a bargain.
Is it cheaper to book a DTW to STL flight and hotel package?
You'll typically save money by securing a DTW to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After choosing your preferred accommodations and flights, consider adding extras including activities, car rentals and tours.
Can I cancel or change the date of my flight from Detroit Metropolitan Wayne County Airport (DTW) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it's possible to cancel or reschedule your DTW to STL flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

0
Origin airport
Detroit Metropolitan Wayne County
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$163
Distance
439 mi

Book with confidence

Book with confidence

Detroit to St. Louis Flights

The cheapest times to fly from Detroit to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Detroit to St. Louis are during the month of October. You can find some of the cheapest flights from Detroit to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Detroit to St. Louis

Sunday is one of the best days to book for cheap flights from Detroit to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Detroit to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Detroit to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $85 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Detroit to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Detroit to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Detroit to St. Louis Flights

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*Available to One Key members.