$16 Car Rental Santa Isabel

Search and Compare from Car Companies in Santa Isabel

I have a discount code

Featured car rental suppliers

Compare from agencies

car suppliers logo

  • protection illustration

    Change your mind

    Penalty-free cancellation on many/select car rentals
  • trophy illustration

    Treat yourself

    One Key members save 10% or more on over 1 million car rentals
    Learn about One Key
  • package illustration

    Shop smart

    Compare car suppliers and package your flight, hotel, and car to save

Top Car Deals in Santa Isabel

* Price found within the past 6 days. Click for updated prices.

Midsize

Toyota Corolla
  • 5 people
  • Unlimited mileage
Carolina, PRI
Toyota Corolla

$16

includes taxes & fees
$16 per day
found 1 day ago
Midsize Toyota Corolla

Economy

Toyota Yaris
  • 5 people
  • Unlimited mileage
Carolina, PRI
Toyota Yaris

$16

includes taxes & fees
$16 per day
found 1 day ago
Economy Toyota Yaris

Compact

Hyundai Accent
  • 5 people
  • Unlimited mileage
Carolina, PRI
Hyundai Accent

$16

includes taxes & fees
$16 per day
found 1 day ago
Compact Hyundai Accent

Special

Vehicle determined upon pick-up Compact or Larger
  • 5 people
  • Unlimited mileage
San Juan, PRI
Vehicle determined  upon pick-up  Compact or Larger

$70

includes taxes & fees
$24 per day
found 1 day ago
Special Vehicle determined upon pick-up Compact or Larger

Standard

Volkswagen Jetta
  • 5 people
  • Unlimited mileage
SAN JUAN, USA
Volkswagen Jetta

$76

includes taxes & fees
$27 per day
found 1 day ago
Standard Volkswagen Jetta

Fullsize

TOYOTA CAMRY
  • 5 people
  • Unlimited mileage
SAN JUAN, PRI
TOYOTA CAMRY

$48

includes taxes & fees
$33 per day
found 1 day ago
Fullsize TOYOTA CAMRY

Mini Van

Kia Sedona
  • 7 people
  • Unlimited mileage
Carolina, PRI
Kia Sedona

$79

includes taxes & fees
$56 per day
found 11 hours ago
Mini Van Kia Sedona

Premium Pickup Regular Cab

Ford F150 AWD
  • 5 people
  • Unlimited mileage
San Juan, PRI
Ford F150 AWD

$147

includes taxes & fees
$69 per day
found 1 day ago
Premium Pickup Regular Cab Ford F150 AWD

Standard Elite SUV

Ford Explorer
  • 7 people
  • Unlimited mileage
CAROLINA, PRI
Ford Explorer

$313

includes taxes & fees
$232 per day
found 1 day ago
Standard Elite SUV Ford Explorer

Don't see what you're looking for?

See all car rentals in Santa Isabel
View all cars

What you need to know for your Santa Isabel car rental

Reasons to book a car rental in and around Santa Isabel

Renting a car in Santa Isabel is an excellent choice for travelers seeking freedom and flexibility while exploring the area. With a rental car, you can easily manage your luggage and create a travel plan that suits your schedule. Whether you are looking for outdoor adventures, beach experiences, or relaxation, having your own vehicle allows you to access various attractions at your own pace. For instance, La Guancha, located 14 miles away, offers a beautiful esplanade perfect for family outings or romantic strolls. If wellness is a priority, Coamo Springs, just 6 miles from Santa Isabel, provides a serene hot spring experience. Adventure seekers can visit Marina de Salinas, 7 miles away, for exciting outdoor activities. Additionally, you can explore nearby cities like Ponce, also 14 miles away, and Salinas, just 7 miles away, which boast attractions such as Parque de Bombas and Playa Pozuelo. With the convenience of a rental car, you can easily navigate between these destinations and fully enjoy your trip to Santa Isabel and its surroundings.

Where to stay around Santa Isabel

  • Salinas: Located only 7 miles away from Santa Isabel, Salinas is an excellent choice for those seeking outdoor adventures and beach experiences. The area boasts popular attractions such as Playa Pozuelo, a beautiful beach perfect for sunbathing and swimming. Additionally, the Marina de Salinas offers numerous opportunities for water sports and exploration. With various dining options nearby, Salinas provides a vibrant atmosphere for travelers looking to enjoy both relaxation and adventure.
  • Ponce: Situated 14 miles from Santa Isabel, Ponce is a city rich in culture and outdoor activities. Visitors can explore La Guancha, an esplanade ideal for enjoying the outdoors with family or on a romantic outing. The historic Parque de Bombas and the Plaza of Delights are notable cultural sites that reflect the city's heritage. With diverse restaurants and recreational areas, Ponce makes for a dynamic stay with ample opportunities for adventure and relaxation.
  • Aibonito: Approximately 15 miles from Santa Isabel, Aibonito stands out for its eco-friendly and outdoor experiences. This city is home to the Finca Don Felix para la Naturaleza, a nature reserve perfect for those who appreciate the natural beauty of Puerto Rico. Coamo Springs, a nearby hotspring, offers a relaxing getaway for wellness seekers. Aibonito’s combination of adventure and culture makes it an inviting destination for travelers looking to immerse themselves in the local environment.

10 tips to save on your car rental in and around Santa Isabel

  1. Use filters to find the right car: Refine your search by selecting vehicle types and features. Whether you need an SUV for additional space, a convertible for warm weather, or an economy car for cost-effectiveness, utilize filters on Expedia to discover the ideal match for your journey.
  2. Book in advance to help lower costs: Rental rates can vary based on demand, so it’s wise to secure your vehicle well before your trip. By booking early, you’re more likely to obtain lower prices and enjoy a wider selection, particularly during peak travel seasons.
  3. Consider a smaller car for savings: Smaller vehicles are typically more affordable to rent and easier to maneuver in crowded areas. Mid-size rentals strike a good balance between cost, comfort, and fuel efficiency.
  4. Age guidelines: Drivers under 30 may encounter higher deposits or daily fees, and certain vehicle categories—such as SUVs or premium cars—might not be available. This can also apply to renters over 70 years old. Always verify the age restrictions prior to booking.
  5. Check fuel policies: Some rental agreements require a full-to-full fuel policy, meaning you must return the car with a full tank to avoid extra charges. This is usually the most cost-effective option. Others may offer full-to-empty or prepaid fuel options, which are also acceptable; just remember to return the vehicle empty in that case.
  6. Save on city and airport pickups: Picking up your rental car at airports often incurs a surcharge, but the added convenience might justify the cost.
  7. Know your payment options: Most car rental companies prefer credit cards for payment.
  8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provides peace of mind in case of unforeseen incidents during your trip. Adding car rental insurance is a straightforward process when booking with Expedia.
  9. Consider unlimited mileage: If you’re planning extensive road trips, seek rentals that offer unlimited mileage to prevent additional charges.
  10. Bring your driver's license and ID: A valid driver's license is necessary to rent a car.

Finding the cheapest car rentals in Santa Isabel

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Santa Isabel into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Santa Isabel and provide you with a list of the cheapest options, with no added fees.

Renting a car in Santa Isabel

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Santa Isabel. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Santa Isabel

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $16.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

We all love being rewarded

One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

Car Rental Information

Popular car types
SUV, Full Size, Economy
Car suppliers available
Our best deal of the day
$16
Our second best deal of the day
$48
Our third best deal of the day
$70
From the airport to your hotel
Airport Transportation
From popular domestic and international airports
Airport Car Rentals

Frequently asked questions

What are the best cheap car rental companies in Santa Isabel?
You can find cheap car rentals in Santa Isabel from $10 a day with Thrifty Car Rental's midsize 2/4 door. Enterprise offers special cars starting from $11 a day, and midsize 2 or 4 door cars starting from $14 a day. Alamo Rent A Car also has premium crossover vehicles starting from $11 a day. Greenmotion provides compact SUVs starting from $11 a day, and Sixt offers compact SUVs starting from $11 a day. Comparing these suppliers on Expedia can help you find a car rental in Santa Isabel that fits your budget. For more options, explore Economy Car Rentals in Santa Isabel.
What are the best luxury car companies in Santa Isabel?
For luxury car rentals in Santa Isabel, you can find premium options through providers like Sixt and Alamo Rent A Car. Sixt offers luxury SUVs starting from $24 a day, providing a high-end driving experience. Alamo Rent A Car also features premium crossover vehicles starting from $11 a day, and their inventory includes Luxury Elite categories. Enterprise also lists Premium Elite options in its inventory. These luxury rentals often come with enhanced comfort and features, making them ideal for travelers seeking a more upscale experience in Santa Isabel. For more options, explore Luxury Car Rentals in Santa Isabel.
Can I rent a car one-way in Santa Isabel?
Yes, a one-way car rental in Santa Isabel is an excellent option for regional road trips, with prices starting from around $10 a day. Providers like Enterprise and Alamo Rent A Car may have flexible one-way policies, allowing you to pick up your vehicle in Santa Isabel and drop it off at a different location. This flexibility is ideal for travelers planning to explore various parts of Puerto Rico without needing to return to their original pickup point. For more options, explore Standard Car Rentals in Santa Isabel.
Can I rent a car round-trip in Santa Isabel?
Yes, Santa Isabel is well suited to round-trip rentals, with prices starting from $10 a day. Picking up and dropping off your rental car at the same location generally avoids one-way drop-off fees, which can make it a cost-effective option for exploring the area and returning to your starting point. Providers like Enterprise and Alamo Rent A Car offer wide round-trip availability, giving you plenty of choice for your travel plans in Santa Isabel. For more options, explore Fullsize Car Rentals in Santa Isabel.
What are the best car rentals in Santa Isabel?
Car rentals in Santa Isabel offer extensive vehicle variety to suit different travel needs. The most popular car classes available include:
  • Special
  • Midsize 2 or 4 door
  • Economy 2 or 4 door
  • Compact 2 or 4 door
  • Compact SUV
Most vehicles come with automatic transmission, making driving convenient. Families visiting Santa Isabel often prefer SUVs or minivans for their spaciousness and luggage capacity, while couples and solo travelers might find economy or compact cars more suitable for easy navigation and fuel efficiency. Choose a car based on your passenger count, luggage requirements, and budget. For more options, explore Minivan Car Rentals in Santa Isabel.
What are the best car rentals in Santa Isabel for solo travelers?
Good car rental options in Santa Isabel for solo travelers are economy and compact classes—small, easy to park, and efficient for one person exploring at their own pace:
  • Economy 2 or 4 door, starting from $15 a day—fits up to 5 people and up to 2 medium suitcases, nimble on city streets and simple to slot into small parking spaces
  • Compact 2 or 4 door, starting from $15 a day—fits up to 5 people and up to 3 medium suitcases with a little more room for luggage while staying fuel-efficient
Both comfortably fit a solo traveler plus a bag or two. If you are planning longer drives, consider sizing up to a compact SUV, starting from $18 a day, for extra highway comfort and a higher ride. For more options, explore Compact Car Rentals in Santa Isabel.
What are the best car rentals in Santa Isabel for couples?
The best car rentals in Santa Isabel for couples balance comfort and easy handling for two:
  • Midsize 2 or 4 door, starting from $14 a day—fits up to 5 people and up to 3 large suitcases with smooth cruising for two
  • Compact SUV, starting from $18 a day—fits up to 5 people and up to 3 medium suitcases with a higher ride for day trips around the region
Both give a couple comfortable seating and trunk space without being hard to park. For a special trip or scenic drives around Santa Isabel, consider a fullsize open air all terrain vehicle, starting from $32 a day, for a unique experience. For more options, explore Midsize Car Rentals in Santa Isabel.
What are the best car rentals in Santa Isabel for families?
The best car rentals in Santa Isabel for families are the ones with room for everyone and their gear:
  • Midsize SUV, starting from $21 a day—seats up to 5 people with room for 3 large suitcases and space for a car seat
  • Mini passenger van, starting from $25 a day—seats up to 8 people with room for 6 large suitcases, ideal for larger families with strollers and full luggage
SUVs and minivans provide ample space for the whole family, including car seats, strollers, and luggage, making them the most comfortable fit for trips around Santa Isabel. Book 4+ weeks ahead, as family-sized vehicles can have lower availability during the peak months of December, July, and March. Consider adding GPS if you are new to the area to help with navigation. For more options, explore SUV Car Rentals in Santa Isabel.
Are there any car rental companies that provide electric cars in Santa Isabel?
Yes, Santa Isabel has electric and hybrid vehicle options available from several rental companies. Enterprise offers electric vehicles starting from $10 a day, and also provides hybrid options starting from $10 a day. Alamo Rent A Car also carries electric vehicles, with options starting from $10 a day. These eco-friendly choices are widely available on Expedia, offering a sustainable way to explore Santa Isabel and potentially save on fuel costs.
What is the best time to book a car in Santa Isabel?
From October, prices in Santa Isabel are typically lower—rentals can start from as little as $11 a day during this period. December tends to be the busiest month, along with July and March, when high demand can lead to higher prices. During major holidays and special events, rates may also fluctuate. Booking 3-4 weeks ahead can help with availability and pricing. Many bookings allow free cancellation 24+ hours before pickup—book early and rebook if rates drop to find a rate that fits your budget.
What are the best car companies in Santa Isabel?
Car rentals in Santa Isabel are available from providers like Enterprise, Alamo Rent A Car, Greenmotion, Sixt, and Avis, offering vehicles suited to local roads and conditions. Enterprise has special and midsize 2 or 4 door options that are easy to park and fuel-efficient for city streets. Alamo Rent A Car offers premium crossover and midsize 2 or 4 door vehicles with more space and stability. Greenmotion provides compact SUV and midsize 4-5 door options. Sixt features compact SUV and midsize SUV vehicles, while Avis rounds out the choices with compact 2 or 4 door and midsize 2 or 4 door vehicles. Choosing a compact class is often beneficial for easy maneuvering and better mileage on longer highway stretches. For more options, explore Premium Car Rentals in Santa Isabel.
What are good day trip destinations from Santa Isabel by rental car?
For travelers looking to explore beyond Santa Isabel, several excellent day trip destinations are easily accessible by rental car, offering diverse experiences for families, couples, and solo adventurers.
  • Coamo Springs, Coamo: Just 7 miles from Santa Isabel, this destination is perfect for a relaxing day trip, offering natural hot springs. The short drive, typically less than 15 minutes, makes it an ideal choice for families with young children or couples seeking a tranquil escape.
  • Condado Beach, San Juan: Located about 49 miles away, Condado Beach offers a vibrant urban beach experience with plenty of dining and shopping options. The drive takes approximately 1 hour, making it a great option for those wanting a mix of city life and beach relaxation.
  • Palmas del Mar Beach, Humacao: Approximately 50 miles from Santa Isabel, this destination provides beautiful beaches and a resort atmosphere, suitable for families and couples. The drive is around 1 hour, offering scenic views along the way.
  • Luquillo Beach, Luquillo: About 64 miles from Santa Isabel, Luquillo Beach is known for its calm waters and popular kiosks, making it a fantastic spot for families. The drive is roughly 1 hour and 15 minutes.
  • Buye Beach, Cabo Rojo: Also around 64 miles away, Buye Beach offers a more serene and picturesque setting, perfect for couples or those seeking a quieter beach day. Expect a drive of about 1 hour and 15 minutes.
For these trips, a comfortable and spacious vehicle is recommended. Families will appreciate the extra room of a midsize SUV starting from $21 a day or a mini passenger van starting from $25 a day, which provides ample space for luggage and beach gear. Couples or solo travelers might find a midsize car starting from $14 a day or a compact SUV starting from $18 a day to be a good balance of comfort and fuel efficiency. Always remember to fuel up before heading out and bring plenty of water, especially for beach excursions. For more options, explore Convertible Car Rentals in Santa Isabel.
Are there any hidden fees when renting a car on Expedia?
Expedia aims to show the key price and important rental details clearly during booking, so you know what to expect before you reserve. In some cases, car rental companies may apply additional charges at pick-up or during the rental, such as security deposits, tolls, fuel charges, extra driver fees, or local requirements, so it's worth checking the supplier's rental terms before you book.
Are there any long-term car rentals in Santa Isabel?
Yes, there are several long-term car rental options available in Santa Isabel. Whether you're planning an extended holiday with the family, relocating temporarily, or simply need a vehicle for several weeks or months, many car rental providers offer flexible long-term rental plans tailored to your needs. Click on our long-term car rental deals page, enter your trip information and then book a ride that suits.
Do you need insurance to rent a car in Santa Isabel?
No, you don't need personal auto insurance to rent a car in most cases. You will, however, be required to purchase some insurance to cover the duration of the rental. Rental companies will offer this insurance when you rent the car. Certain personal car insurance policies can also be applied to rental cars, and travelers can even use non-owner car insurance if they rent cars often but don't have a car of their own. Additionally, some car rentals simply include rental car insurance within the price of the rental.
How much does it cost to rent a car in Santa Isabel?
Budget car rental in Santa Isabel can be easy to find, with prices based on rates seen within the past seven days from $16. To find some of the cheapest options, sort your search results by price and use filters to match your budget and travel needs. For added flexibility, it's also worth exploring one-way car rentals.
What are the top car rental deals in Santa Isabel?
No matter what kind of vehicle you're looking for, Expedia makes it easy to find a great car rental deal in Santa Isabel. The easiest way to get a good deal on a rental car is to use our filters. At the top of the filter list, you'll find a section featuring our best car rental offers. Check the filter for "Great Deal," and your search results will be filled with specials. Compare offers from trusted rental providers, choose the option that fits your trip, and book with confidence. For even more value, bundle your Santa Isabel car rental with a hotel or flight to unlock additional savings.
What do I need to rent a car in Santa Isabel?
To rent a car in Santa Isabel, a current driver's license and a credit card in the same name are essential. If you're opting out of the company's insurance plan, then you may also need proof of other coverage. Rules may differ between rental companies, so read through your policy.
What happens if I need to cancel my Santa Isabel car rental?
If you need to cancel your Santa Isabel car rental, read over the policy to be sure, but almost all prepaid rentals are eligible for a complete refund if you notify us at least six hours prior to the pickup time, though there may be some exclusions so check your itinerary for more information, or just click through to our Customer Service Portal.
Why should I rent a car in Santa Isabel with Expedia?
Booking your car rental on Expedia makes it easier to get more out of your trip from the start. With a wide choice of car rentals, you can compare prices, suppliers and deals all in one place, then bundle your car with a hotel which could help you save even more. Join our free One Key™ travel rewards program to instantly unlock additional savings.

Explore a world of travel with Expedia