Santa Isabel Vacations from $307

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Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Lazy Parrot Inn
Ola Boutique Hotel
Urbana Hotel
Aire de O:live
THE BUOY
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Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9 Santa Isabel
$81 nightly
The price is $88 total per night from Dec 6 to Dec 7
$88 total
Dec 6 - Dec 7
Total with taxes and fees
7.8/10 Good! (306 reviews)
Good thing Walmart nearby

Reviewed on Nov 5, 2025

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$160 nightly
The price is $175 total per night from Dec 14 to Dec 15
$175 total
Dec 14 - Dec 15
Total with taxes and fees
9.6/10 Exceptional! (20 reviews)
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again

Reviewed on Sep 7, 2025

Hacienda del Sur
Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary

Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary

Santa Isabel PR
$551 nightly
The price is $584 total per night from Nov 19 to Nov 20
$584 total
Nov 19 - Nov 20
Total with taxes and fees
10/10 Exceptional! (1 review)
Such an amazing place. Views are spectacular. The outside family area was our favorite part. The pool was perfect too. My family and I were very comfortable here. Definitely look forward to coming back!

Reviewed on Oct 7, 2025

Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Mercedita Airport (PSE)
Population
7,300
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Coamo Springs, Playa La Ochenta and Marina de Salinas

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $307 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.