Santa Isabel Vacations from $566
Book a Hotel + Flight or Car together to unlock savings
Photo by Eddie Melendez
Your Santa Isabel Vacation
Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.
The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.
Urbana Hotel
San Juan Antiguo
Save 100% on your flight
Price was $1,151, price is now $566 per person
$566
per person
Jan 1 - Jan 6
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.6/10 Excellent! (368 reviews)
The room was clean when I arrived. The AC worked throughout my entire stay which was great considering how hot it can get. The only things that I disliked were that they didn’t have a dresser. It was just a rack and some hangers. They also don’t have a microwave in the room. You would have to go to the check in area and heat up over there which is inconvenient.
Reviewed on Oct 15, 2025
OLV Fifty Five - Adults Only
Condado
Save 100% on your flight
Price was $2,296, price is now $1,281 per person
$1,281
per person
Jan 1 - Jan 6
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.6/10 Excellent! (563 reviews)
I absolutely LOVED this hotel. My stay was relaxing. It was peaceful, clean, the staff (front desk, housekeeping and restaurant staff) were kind. Hotel was 20mins or less to different locations I visited.
Reviewed on Oct 18, 2025
San Agustin Apartments
San Juan Antiguo
Save 100% on your flight
Price was $1,209, price is now $692 per person
$692
per person
Jan 1 - Jan 6
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (420 reviews)
The area was a little sketchy it was an old building but the smell of the hallway was putrid. The apt itself was clean. The bathroom and hallway very narrow. We had 2 rooms and they could not accommodate us together in the same building we were in 2 different buildings the other room someone got bit all over with bed bugs
Reviewed on Oct 21, 2025
Romeo Gay Hotel
San Juan Antiguo
Save 100% on your flight
Price was $1,090, price is now $647 per person
$647
per person
Jan 1 - Jan 6
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9/10 Wonderful! (100 reviews)
The property is perfect to couples and relaxing days
Reviewed on Oct 21, 2025
Don't see what you're looking for?
See all available trips from Columbus to Santa Isabel
View all tripsSanta Isabel Hotel Deals
Hotel Las Vegas
PR 153, Km 2.9, Santa Isabel
$83 nightly
The price is $90 total per night from Nov 5 to Nov 6
$90 total
Nov 5 - Nov 6
Total with taxes and fees
7.8/10 Good! (302 reviews)
The only things i stay there for a week and not one time they didn't bring me clean towels oh blankets oh picked up the garbage i have to buy towel and take the garbage outside for then to grab it
Reviewed on Oct 18, 2025
Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
$152 nightly
The price is $166 total per night from Nov 6 to Nov 7
$166 total
Nov 6 - Nov 7
Total with taxes and fees
9.6/10 Exceptional! (20 reviews)
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again
Reviewed on Sep 7, 2025
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$343 nightly
The price is $364 total per night from Oct 26 to Oct 27
$364 total
Oct 26 - Oct 27
Total with taxes and fees
8.8/10 Excellent! (44 reviews)
Loved it!!!!! Spacious clean! Internet did not work but to be honest we did not need it at all.
Reviewed on Sep 7, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Mercedita Airport (PSE) |
Population | 7,300 |
Max Temp Winter | 80ºF |
Max Temp Summer | 85ºF |
Top Sights | Coamo Springs, Playa La Ochenta and Marina de Salinas |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
- All-inclusive Resorts in Puerto Rico
- Jauca I Hotels
- Villas in Rio Canas Abajo
- Rio Canas Abajo Hotels
- Hotels near Coamo Springs
- Salinas Hotels
- Motels in Salinas
- Hostels in Salinas
- Villas in Salinas
- Guest Houses in Salinas
- Apartments in Salinas
- Condo Rentals in Salinas
- Vacation Homes in Salinas
- 5 Star Hotels in Salinas
- Resorts in Salinas
- 4 Star Hotels in Salinas
- Hotels near Marina de Salinas
- Coamo Hotels
- Villas in Coamo
- Vacation Homes in Coamo
- Motels in Coamo
- Resorts in Coamo
- Apartments in Coamo
- B&B in Coamo
- Condo Rentals in Coamo
- Guest Houses in Coamo
- Juana Diaz Hotels
- Motels in Juana Diaz
- Vacation Homes in Juana Diaz
- Apartments in Juana Diaz
- Guest Houses in Juana Diaz
- 3 Star Hotels in Juana Diaz
- Resorts in Juana Diaz
- 5 Star Hotels in Juana Diaz
- Villas in Juana Diaz
- Condo Rentals in Juana Diaz
- Isla Caja de Muertos Hotels
- 3 Star Hotels in Isla Caja de Muertos
- Villas in Isla Caja de Muertos
- Flights to Puerto Rico Island
- Flights to Salinas
- Flights from Salinas
- Flights to Coamo
- Flights from Coamo
- Flights to Juana Diaz
- Flights from Juana Diaz
- Flights to Isla Caja de Muertos
- Flights from Mercedita
- Flights from Orlando (MCO) to Ponce (PSE)
- Flights from New York (JFK) to Ponce (PSE)
- Flights from San Juan (SJU) to Ponce (PSE)
- Flights from Philadelphia (PHL) to Ponce (PSE)
- Flights from Tampa (TPA) to Ponce (PSE)
- Flights from Chicago (ORD) to Ponce (PSE)
- Flights from Miami (MIA) to Ponce (PSE)
- Flights from Hartford (BDL) to Ponce (PSE)
- Flights from Boston (BOS) to Ponce (PSE)
- Flights from Fort Lauderdale (FLL) to Ponce (PSE)
- Flights to Mercedita
- Flights from Raleigh (RDU) to Ponce (PSE)
- Flights from Atlanta (ATL) to Ponce (PSE)
- Flights from Dallas (DFW) to Ponce (PSE)
- Flights from Houston (IAH) to Ponce (PSE)
- JetBlue Airways New York (JFK) to Ponce (PSE) flights
- JetBlue Airways Orlando (MCO) to Ponce (PSE) flights
- Flights from Baltimore (BWI) to Ponce (PSE)
- Flights from Jacksonville (JAX) to Ponce (PSE)
- Flights from Cleveland (CLE) to Ponce (PSE)
- Flights from Detroit (DTW) to Ponce (PSE)
- Puerto Rico Island Vacations
- Visit Rio Canas Abajo
- Coamo Springs
- Visit Urbanization Las Fuentes de Coamo
- Salinas Vacations
- Marina de Salinas
- Visit Salinas
- Puerto Rico National Guard Museum
- Coamo Vacations
- Juana Diaz Vacations
- Visit Coamo
- Isla Caja de Muertos Vacations
- Visit Juana Diaz
- Visit Isla Caja de Muertos
- Car rentals near Rio Canas Abajo
- Car rentals near Coamo Springs
- Car rentals near Salinas
- Enterprise Rental Cars in Salinas
- Car rentals near Puerto Rico National Guard Museum
- Car rentals near Coamo
- Car rentals near Juana Diaz
- Enterprise Rental Cars in Juana Diaz
- Alamo Rent A Car Rental Cars in Juana Diaz
- Car rental Ponce Airport (PSE)
- Thrifty Car Rental Rental Cars in Mercedita
- Hertz Rental Cars in Mercedita
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.