Title: Santa Isabel Vacation Packages 2026 from $768 | Expedia.com [Santa Isabel Travel Guide](https://expedia.com/Santa-Isabel.dx6035096)[Hotels in Santa Isabel](https://expedia.com/Santa-Isabel-Hotels.d6035096.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel](https://expedia.com/Santa-Isabel-Vacation-Rentals.d6035096.Travel-Guide-VacationRentals)[Flights to Santa Isabel](https://expedia.com/Cheap-Flights-To-Santa-Isabel.d6035096.Travel-Guide-Flights)[Car Rentals in Santa Isabel](https://expedia.com/Car-Rentals-In-Santa-Isabel.d6035096.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6035096/9acf998c-758c-4442-906a-abe4784b9ebb.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Isabel Vacations from $768 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santa Isabel Vacation Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put [Coamo Springs](https://www.expedia.com/Coamo-Springs-Coamo.d6081889.Vacation-Attraction) and [Playa La Ochenta](https://www.expedia.com/Playa-La-Ochenta-Salinas.d553248635980609624.Vacation-Attraction) on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like. ## The Latest Santa Isabel vacation packages Price found within the past 48 hours. Click for updated prices. ![Urbana Hotel](https://images.trvl-media.com/lodging/91000000/90550000/90546000/90545906/6c8b699a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Urbana Hotel San Juan Antiguo Save 100% on your flight $768 per person May 8 - May 15 found 1 day ago Roundtrip flight included Boston (BOS) to San Juan (SJU) 8.6/10 Excellent! (389 reviews) Staff was very helpful and quick to respond with any questions. The room was perfect for a quick one night stay as it was comfy and cozy. Would definitely stay again! Reviewed on Feb 22, 2026 ![Olive Boutique Hotel, A Small Luxury Hotel of the World (Adults Only)](https://images.trvl-media.com/lodging/6000000/5200000/5196300/5196263/66510c0c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Olive Boutique Hotel, A Small Luxury Hotel of the World (Adults Only) Condado Save 100% on your flight $1,136 per person Apr 2 - Apr 7 found 1 day ago Roundtrip flight included Boston (BOS) to San Juan (SJU) 9/10 Wonderful! (645 reviews) Room is well-appointed. Staff friendly, short of training, so simple services are even challenging. Olive dining was at sister property -- very poor set-up. Reviewed on Feb 25, 2026 ![Hotel Puerto Valdes](https://images.trvl-media.com/lodging/70000000/69380000/69371400/69371387/0dc1a939_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Puerto Valdes San Juan Antiguo $1,174 per person Apr 19 - Apr 26 found 1 day ago Roundtrip non-stop flight included Boston (BOS) to San Juan (SJU) 9/10 Wonderful! (500 reviews) Great staff very large oops. NO hot water, no coffee available per staff good location Reviewed on Feb 24, 2026 ![Aire de O:live](https://images.trvl-media.com/lodging/1000000/530000/527600/527599/8d4c39ed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Aire de O:live Isla Verde $1,576 per person Apr 19 - Apr 26 found 1 day ago Roundtrip non-stop flight included Boston (BOS) to San Juan (SJU) 9/10 Wonderful! (328 reviews) Nice little boutique hotel in a great spot however, the staff is really hit and miss and the place is in need of a touch up here and there for sure. Reviewed on Feb 25, 2026 ![Romeo Gay Hotel](https://images.trvl-media.com/lodging/105000000/104580000/104571300/104571256/c3574a90_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Romeo Gay Hotel San Juan Antiguo Save 100% on your flight $806 per person May 8 - May 15 found 1 day ago Roundtrip flight included Boston (BOS) to San Juan (SJU) 9/10 Wonderful! (121 reviews) Great stay, room was very clean had an industrial vibe. Property was very nice overall. Staff very friendly and helpful. Plenty of parking in the lot next to the property. Stayed two nights with my wife after returning to San Juan following a wedding over the weekend in Guanica. Reviewed on Feb 25, 2026 Don't see what you're looking for? See all available trips from Columbus to Santa Isabel [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-26/2026-04-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SJU&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6035096) ## Santa Isabel Hotel Deals ![Hotel Las Vegas](https://images.trvl-media.com/lodging/29000000/28800000/28799500/28799456/abeca2f0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Las Vegas PR 153, Km 2.9 Santa Isabel $79 nightly $86 total Mar 25 - Mar 26 Total with taxes and fees 8/10 Very Good! (331 reviews) Good staff Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&selected=28799456&PinnedHotelID=28799456&HadPinnedHotel=true®ionId=6035096) ![Hacienda del Sur](https://images.trvl-media.com/lodging/114000000/113270000/113268500/113268492/3e50b06a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hacienda del Sur Carr 545 KM 1.5, Sector Gabia Santa Isabel $141 nightly $154 total Mar 4 - Mar 5 Total with taxes and fees 9.6/10 Exceptional! (31 reviews) This place was so impressive. The grounds are immaculate. The rooms are super clean and Modern. The Pool area is very calming. The food from the bar area was really tasty. Everyone was very nice and accommodating. I will definitely stay there again. Reviewed on Feb 20, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=113268492&PinnedHotelID=113268492&HadPinnedHotel=true®ionId=6035096) ![Caribbean Paradise – Oceanfront Villa with Infinity Pool & Garden Sanctuary](https://images.trvl-media.com/lodging/120000000/119880000/119870600/119870571/65d91bdd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Caribbean Paradise – Oceanfront Villa with Infinity Pool & Garden Sanctuary Santa Isabel PR 9.6/10 Exceptional! (4 reviews) It is a very small house it really should not be marketed for more than 4 people the single seat bed is not good for an adult. Once you open de sofa bed there is no space to socialize inside the house. Having a beach front property with a pool and not provide beach towels is not convenient at all. ... Reviewed on Jan 4, 2026 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=119870571&PinnedHotelID=119870571&HadPinnedHotel=true®ionId=6035096) [](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=119870571&PinnedHotelID=119870571&HadPinnedHotel=true®ionId=6035096) [See all 316 properties in Santa Isabel](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F27%2F2026&endDate=2%2F28%2F2026®ionId=6035096) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santa Isabel Vacation Packages ## Santa Isabel Essential Information | Language | Spanish | | --------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Mercedita Airport (PSE) | | Population | 7,300 | | Max Temp Winter | 80ºF | | Max Temp Summer | 85ºF | | Top Sights | [Coamo Springs](https://www.expedia.com/Coamo-Springs-Coamo.d6081889.Vacation-Attraction), [Playa La Ochenta](https://www.expedia.com/Playa-La-Ochenta-Salinas.d553248635980609624.Vacation-Attraction) and [Marina de Salinas](https://www.expedia.com/Marina-De-Salinas-Salinas.d553248621533158760.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Santa Isabel vacation package cost? ### What are the cheapest months to go to Santa Isabel? ### How many days is enough for Santa Isabel? ### How to find the best Santa Isabel package deals? ### Is it cheaper to book a Santa Isabel vacation as a package? ### When to book a vacation package to Santa Isabel? ### Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages? ## Explore a world of travel with Expedia - Lodging 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