Santa Isabel Vacations from $635

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Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Casa Ciana

Casa Ciana

Santurce
Save 100% on your flight
$635
per person
Oct 20 - Oct 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.6/10 Exceptional! (514 reviews)
The stay was literally in the heart of San Juan! Everything is close by! You can literally walk to any restaurants and bar! They have their own parking lot as well! Definitely recommend the stay

Reviewed on Aug 31, 2026

Isla Verde Beachfront Retreat With Parking

Isla Verde Beachfront Retreat With Parking

Isla Verde
Save 100% on your flight
$788
per person
Nov 11 - Nov 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
10/10 Exceptional! (4 reviews)
WALD HAUS by DW

WALD HAUS by DW

Save 100% on your flight
$2,606
per person
Oct 3 - Oct 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (11 reviews)
The home itself is absolutely stunning but the road to the villa is not just narrow, it's washed out in many places, we struggled to navigate the potholes even with a jeep and an SUV, I would not drive it at night. There are great amenities like the fridge and bathroom downstairs, the coffee / cocktail bar is fabulous.The kitchen was well-stocked with basic spices and supplies but it was crawling with roaches. Wifi is spotty so be sure to have the guidebook downloaded and screenshots of the phone number to call because the phone number posted throughout the villa is not functioning. Even in August the combination of ACs, fans, and breezes kept the temprature very comfortable. Excellent pool, though very little shallow area, if you're traveling with kids or weaker swimmers.

Reviewed on Aug 13, 2026

VILLA JOYUDA

VILLA JOYUDA

Save 100% on your flight
$3,592
per person
Oct 11 - Oct 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to San Juan (SJU)
10/10 Exceptional! (1 review)
It has everything you may need and more

Reviewed on Nov 5, 2025

Villa Azure Ocean Suites

Villa Azure Ocean Suites

Santurce
Save 100% on your flight
$2,268
per person
Nov 19 - Nov 22
found 11 hours ago
Roundtrip flight included
New York (JFK) to San Juan (SJU)
10/10 Exceptional! (3 reviews)
We had such an amazing time at Villa Azure! Our group of 16 couldn’t get enough of the gorgeous ocean views, and the fact that the beach was just a short walk away was perfect. The house itself was super cozy and beautifully decorated—plenty of space for everyone but still felt like home. We spent hours relaxing by the pool and enjoying the outdoor area, which was perfect for hanging out together. We can’t wait to come back!

Reviewed on Oct 21, 2024

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Stay near popular Santa Isabel attractions

Carribbean Cinemas Santa Isabel

Caribbean Cinemas Santa Isabel offers a comfortable venue for international blockbusters and Spanish-language films. Arrive early on weekends to secure preferred seating at this community entertainment hub.
See properties

What to do in Santa Isabel

Puerto Rico Half-Day Shark Diving

Puerto Rico Half-Day Shark Diving

$225
per adult
Puerto Rico Half-Day Shark Diving
See all activities in Santa Isabel

Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

PR 153, Km 2.9 Santa Isabel
$74 nightly
$81 total
Sep 15 - Sep 16
Total with taxes and fees
Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

Carr 545 KM 1.5, Sector Gabia Santa Isabel
$131 nightly
$143 total
Sep 8 - Sep 9
Total with taxes and fees
Hacienda del Sur
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
9.8/10 Exceptional! (8 reviews)
"Fantastic stay with my family. It’s a beautiful property with incredible views. The pool was amazing and the kids really enjoyed their time here. The host was great and very responsive. The property was very clean and secure. We would definitely stay here again!!"

Reviewed on Jun 8, 2026

Get rates
3BR Puerto Rico Villa w Pool | Aqua Bella 1
See all 322 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Mercedita Airport (PSE)
Population
7,300
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Coamo Springs, Playa La Ochenta and Marina de Salinas

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $635 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.