Santa Isabel Vacations from $688

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Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Puerto Valdes

Hotel Puerto Valdes

Puerta de Tierra
Save 100% on your flight
$688
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.8/10 Excellent! (713 reviews)
Isla Verde Beachfront Retreat With Parking

Isla Verde Beachfront Retreat With Parking

Isla Verde
$925
per person
Oct 6 - Oct 13
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
10/10 Exceptional! (2 reviews)
OLV Fifty Five - Adults Only

OLV Fifty Five - Adults Only

Condado
Save 100% on your flight
$1,210
per person
Oct 20 - Oct 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.8/10 Excellent! (750 reviews)
The room was exactly as pictured. All the staff were friendly and our housekeeper did an exceptional job cleaning the room each day. The property is in a walkable area and walking distance to the beach.

Reviewed on Aug 18, 2026

Trópica Beach Hotel

Trópica Beach Hotel

Santurce
Save 100% on your flight
$800
per person
Oct 20 - Oct 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.4/10 Exceptional! (959 reviews)
Terrible, not a professional business at all

Reviewed on Aug 19, 2026

Lazy Parrot Inn

Lazy Parrot Inn

Save 100% on your flight
$722
per person
Oct 20 - Oct 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (1,001 reviews)
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Stay near popular Santa Isabel attractions

Carribbean Cinemas Santa Isabel

Caribbean Cinemas Santa Isabel offers a comfortable venue for international blockbusters and Spanish-language films. Arrive early on weekends to secure preferred seating at this community entertainment hub.
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What to do in Santa Isabel

Puerto Rico Half-Day Shark Diving

Puerto Rico Half-Day Shark Diving

$225
per adult
Puerto Rico Half-Day Shark Diving
See all activities in Santa Isabel

Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

PR 153, Km 2.9 Santa Isabel
$73 nightly
$79 total
Aug 28 - Aug 29
Total with taxes and fees
8/10 Very Good! (374 reviews)
"Los empleados muy atentos y serviciales.."

Reviewed on Aug 16, 2026

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

Carr 545 KM 1.5, Sector Gabia Santa Isabel
$127 nightly
$139 total
Aug 23 - Aug 24
Total with taxes and fees
9.6/10 Exceptional! (63 reviews)
"Desde que lleguamos al hotel se siente un calor bien familiar, nos recibieron con ese amor, empezando desde los guardias de seguridad siempre pendiente a todo tiempo, los cuartos al 100% limpios, y bien olorosos, el personal de mantenimiento los mejores bien servicial a todo tiempo, la comida ruquisimaaaa ..."

Reviewed on Aug 17, 2026

Hacienda del Sur
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
9.8/10 Exceptional! (8 reviews)
"Fantastic stay with my family. It’s a beautiful property with incredible views. The pool was amazing and the kids really enjoyed their time here. The host was great and very responsive. The property was very clean and secure. We would definitely stay here again!!"

Reviewed on Jun 8, 2026

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3BR Puerto Rico Villa w Pool | Aqua Bella 1
See all 320 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Mercedita Airport (PSE)
Population
7,300
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Coamo Springs, Playa La Ochenta and Marina de Salinas

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $688 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.