Santa Isabel Vacations from $652

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Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Lazy Parrot Inn

Lazy Parrot Inn

3 out of 5
Save 100% on your flight
Price was $1,148, price is now $652 per person
$652
per person
Jul 6 - Jul 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (1,003 reviews)
It was cozy and comfortable

Reviewed on May 3, 2026

Isla Verde Beachfront Retreat With Parking

Isla Verde Beachfront Retreat With Parking

2 out of 5
Isla Verde
Save 100% on your flight
Price was $1,576, price is now $807 per person
$807
per person
Jun 19 - Jun 23
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
10/10 Exceptional! (1 review)
The room was clean and spacious!

Reviewed on Mar 24, 2026

Grand Reserve by Otium

Grand Reserve by Otium

3 out of 5
Zarzal
Save 100% on your flight
Price was $4,237, price is now $2,502 per person
$2,502
per person
Jul 17 - Jul 24
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
No reviews
Paradise Villas & Vacations

Paradise Villas & Vacations

3.5 out of 5
Sabana
Save 100% on your flight
Price was $1,835, price is now $1,159 per person
$1,159
per person
Jul 6 - Jul 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
10/10 Exceptional! (11 reviews)
We thoroughly enjoyed our vacation here and it is indeed as described. The property is serene and we loved that we woke up to birds, iguanas, and even saw new crabs that in hiding. It is a lovely, exceptional place indeed. Our stay will be etched in our memories forever and we'd love to be back!

Reviewed on May 2, 2026

Serenity by Otium

Serenity by Otium

2 out of 5
Save 100% on your flight
Price was $2,011, price is now $1,290 per person
$1,290
per person
Jul 6 - Jul 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
No reviews
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Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9 Santa Isabel
$78 nightly
The price is $85 total per night from May 7 to May 8
$85 total
May 7 - May 8
Total with taxes and fees
8/10 Very Good! (345 reviews)
Not sure if there was a vending machine, ice maker or microwave. It would be great to have some kind of food when it is late at night. Not sure if they have a kitchen where they could be a microwave and ice maker. I did not ask for these, but also there were no sign of them having them. There is ...

Reviewed on May 5, 2026

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$130 nightly
The price is $141 total per night from May 13 to May 14
$141 total
May 13 - May 14
Total with taxes and fees
9.8/10 Exceptional! (42 reviews)
Lugar acogedor y el personal muy atento.

Reviewed on Apr 20, 2026

Hacienda del Sur
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
9.8/10 Exceptional! (6 reviews)
The outdoor living areas were set up very well! The pool with the ocean view was incredible, me and my family really enjoyed our stay here.I recommend reserving the entire outdoor living space for your family to enjoy, or renting both homes for the privacy. That’s what we did and it was perfect.

Reviewed on Apr 22, 2026

Get rates
3BR Puerto Rico Villa w Pool | Aqua Bella 1
See all 320 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Mercedita Airport (PSE)
Population
7,300
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Coamo Springs, Playa La Ochenta and Marina de Salinas

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $652 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.