Santa Isabel Vacations from $301
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Photo by Eddie Melendez
Your Santa Isabel Vacation
Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.
The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.
Serena Boutique Hotel
Save 100% on your flight
Price was $590, price is now $301 per person
$301
per person
Jan 23 - Jan 26
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
18.8/10 Exceptional! (219 reviews)
This was an amazing stay. Ricardo and his family were so hospitable, helpful and welcoming.They truly made our vacation wonderful and we will be returning to Serena Boutique Hotel. The room was clean, the hot tub was perfect, the views are breathtaking. We felt like we were in a home away from home. I can't say enough good things about this place, what a HIDDEN GEM!
Reviewed on Nov 17, 2025
Urbana Hotel
San Juan Antiguo
Price was $1,179, price is now $560 per person
$560
per person
Jan 23 - Jan 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
17.2/10 Exceptional! (389 reviews)
My stay at Urbana Hotel was amazing. From the moment I arrived, the service was excellent and the staff made me feel truly welcomed. The overall experience was smooth, comfortable, and exceeded my expectations. I highly recommend this hotel to anyone looking for great service and a memorable stay.
Reviewed on Nov 20, 2025
Hotel Puerto Valdes
San Juan Antiguo
Save 100% on your flight
Price was $802, price is now $414 per person
$414
per person
Feb 2 - Feb 6
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
18/10 Exceptional! (500 reviews)
Everything about my stay was wonderful. The staff were friendly and welcoming, and the room was spotless. The view was incredible—I could even see when the cruise ships came in. The food at the restaurant was delicious; I had the salmon, and it was cooked perfectly. They also have a great selection for dinner. The neighborhood felt safe and quiet, and it’s easy to walk around and explore. Overall, a 10/10 stay. Highly recommend!
Reviewed on Nov 13, 2025
ESJ Beach Hotel
Isla Verde
Price was $899, price is now $466 per person
$466
per person
Feb 5 - Feb 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
13.6/10 Exceptional! (4,221 reviews)
The overall stay was good. Hotel needs a bit of tlc and pool being renovated, which I was not told. I arrived early and asked front desk if I could get a call when the room was available but that never happened.
Reviewed on Nov 19, 2025
Hotel Milano
Old San Juan
Price was $2,234, price is now $1,183 per person
$1,183
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
18.4/10 Exceptional! (101 reviews)
Great location and a great room! They have a spot to hold bags which is great to be able to explore more. Friendly staff.
Reviewed on Nov 14, 2025
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Santa Isabel Hotel Deals
Hotel Las Vegas
PR 153, Km 2.9 Santa Isabel
$81 nightly
The price is $88 total per night from Dec 5 to Dec 6
$88 total
Dec 5 - Dec 6
Total with taxes and fees
7.8/10 Good! (306 reviews)
Good thing Walmart nearby
Reviewed on Nov 5, 2025
Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$161 nightly
The price is $176 total per night from Nov 30 to Dec 1
$176 total
Nov 30 - Dec 1
Total with taxes and fees
9.6/10 Exceptional! (20 reviews)
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again
Reviewed on Sep 7, 2025
Caribbean Paradise – Oceanfront Villa with Infinity Pool & Garden Sanctuary
Santa Isabel PR
10/10 Exceptional! (1 review)
Such an amazing place. Views are spectacular. The outside family area was our favorite part. The pool was perfect too. My family and I were very comfortable here. Definitely look forward to coming back!
Reviewed on Oct 7, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Mercedita Airport (PSE) |
Population | 7,300 |
Max Temp Winter | 80ºF |
Max Temp Summer | 85ºF |
Top Sights | Coamo Springs, Playa La Ochenta and Marina de Salinas |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.