Santa Isabel Vacations from $456

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Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Ola Boutique Hotel
Las Casitas Village at El Conquistador
Sandy Beach Hotel
The Oliver Hotel
San Agustin Apartments
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Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
$83 nightly
The price is $91 total per night from Aug 23 to Aug 24
$91 total
Aug 23 - Aug 24
Total with taxes and fees
7.8/10 Good! (293 reviews)
"Easy access"

Reviewed on Jul 28, 2025

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
$156 nightly
The price is $171 total per night from Sep 1 to Sep 2
$171 total
Sep 1 - Sep 2
Total with taxes and fees
9.4/10 Exceptional! (18 reviews)
Hidden gem
"I stayed here for the Bad Bunny residency because I rather stay closer to family, and I feel like I found a hidden gem in the south of PR. From the moment I walked in, everyone (especially Rosie) was so attentive. I stayed alone a few days before my friend arrived, but I didn't feel alone. The owner's ..."

Reviewed on Aug 11, 2025

Hacienda del Sur
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
$343 nightly
The price is $364 total per night from Aug 26 to Aug 27
$364 total
Aug 26 - Aug 27
Total with taxes and fees
8.8/10 Excellent! (41 reviews)
Relax and Unwind
"We needed a place as a base camp to visit family while also large enough to host everyone during our visit. The host accommodated a last minute request and the rental did not disappoint. This house is located right on the ocean with direct access to a small beach area with plenty of space for family ..."

Reviewed on Jul 24, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $456 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.