Santa Isabel Vacations from $566

Book a Hotel + Flight or Car together to unlock savings

Photo by Eddie Melendez

Your Santa Isabel Vacation

Book a Santa Isabel vacation package and get set for an awesome adventure. Well known for its lively atmosphere and welcoming locals, there's loads to love about this city. When the time comes to get out and see the sights, be sure to put Coamo Springs and Playa La Ochenta on the to-do list for your trip to Santa Isabel. Expedia has what you need to escape your routine. Tailor your vacation to Santa Isabel to suit your travel style, whatever that may look like.

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Urbana Hotel
Hotel Puerto Valdes
OLV Fifty Five - Adults Only
San Agustin Apartments
Romeo Gay Hotel
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Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
$83 nightly
The price is $90 total per night from Nov 5 to Nov 6
$90 total
Nov 5 - Nov 6
Total with taxes and fees
7.8/10 Good! (302 reviews)
The only things i stay there for a week and not one time they didn't bring me clean towels oh blankets oh picked up the garbage i have to buy towel and take the garbage outside for then to grab it

Reviewed on Oct 18, 2025

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
$152 nightly
The price is $166 total per night from Nov 6 to Nov 7
$166 total
Nov 6 - Nov 7
Total with taxes and fees
9.6/10 Exceptional! (20 reviews)
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again

Reviewed on Sep 7, 2025

Hacienda del Sur
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
$343 nightly
The price is $364 total per night from Oct 26 to Oct 27
$364 total
Oct 26 - Oct 27
Total with taxes and fees
8.8/10 Excellent! (44 reviews)
Loved it!!!!! Spacious clean! Internet did not work but to be honest we did not need it at all.

Reviewed on Sep 7, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Mercedita Airport (PSE)
Population
7,300
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Coamo Springs, Playa La Ochenta and Marina de Salinas

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $566 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're looking to score a cheap Santa Isabel vacation package, consider visiting in September, October and December. You'll generally find lower rates on hotels and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santa Isabel?
Typically, a handful of days is enough to explore the main sights during your Santa Isabel vacation. But if you'd like to have time to rest or take day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Bagging a cheap Santa Isabel package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santa Isabel package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component individually. And you'll still enjoy the freedom to create a personalized Santa Isabel vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel break is meant to be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.