Dona Ana Vacation Rentals

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Vacation Rentals in Dona Ana

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

2.0 star property
9.6 out of 10, Exceptional, (7)
$165 nightly
The price is $179
Oct 13 - Oct 14
Total with taxes and fees
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

Desert Pool Oasis located in the heart of Las Cruces

9.8 out of 10, Exceptional, (124)
"An absolutely wonderful experience. Great house, nice and quiet neighborhood. And most of all the host is awesome!"
Desert Pool Oasis located in the heart of Las Cruces

Elvis’s Cozy Casa- Charming 3 bedroom,2 bathroom home w/ Mountain views

10.0 out of 10, Exceptional, (16)
"Next time we're passing through the area will attempt to stay here "
$190 nightly
The price is $206
Oct 8 - Oct 9
Total with taxes and fees
Elvis’s Cozy Casa- Charming 3 bedroom,2 bathroom home w/ Mountain views

New Casita/Suite No cleaning fee.

9.6 out of 10, Exceptional, (20)
"Great place to stop for the night. "
$123 nightly
The price is $133
Oct 5 - Oct 6
Total with taxes and fees
New Casita/Suite No cleaning fee.

Las Cruces Southwest Charm with Pool, Hot Tub & Mountain Views

10.0 out of 10, Exceptional, (22)
"The home was great! Very relaxing and the hot tub was fantastic!"
Las Cruces Southwest Charm with Pool, Hot Tub & Mountain Views

60-acre custom home with breathtaking views of city of Las Cruces & Organs!

10.0 out of 10, Exceptional, (22)
"Everything you need, plus more. They are the best hosts!!"
$1,844 nightly
The price is $1,964
Oct 6 - Oct 7
Total with taxes and fees
60-acre custom home with breathtaking views of city of Las Cruces & Organs!

Yucca House | Views, Jetted Bath, Central Retreat

10.0 out of 10, Exceptional, (33)
"We’ve stayed at Yucca House a few times and it is always clean and as described. Wendy is very responsive A great place to stay when in Las Cruces"
$273 nightly
The price is $311
Oct 7 - Oct 8
Total with taxes and fees
Yucca House | Views, Jetted Bath, Central Retreat

Quaint Southwest Mesilla Home - Pet Friendly

9.8 out of 10, Exceptional, (40)
"I had a lovely, peaceful stay. The house was great. I also enjoyed going to the nearby Picacho Roasters coffee shop. "
$182 nightly
The price is $197
Oct 6 - Oct 7
Total with taxes and fees
Quaint Southwest Mesilla Home - Pet Friendly

Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio

10.0 out of 10, Exceptional, (3)
"Beautiful home, really enjoyed our stay. Would recommend this home to others. "
$163 nightly
The price is $176
Oct 5 - Oct 6
Total with taxes and fees
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio

Year Round Heated Pool, Hot Tub, Pet Friendly

10.0 out of 10, Exceptional, (51)
"Family together for graduation"
Year Round Heated Pool, Hot Tub, Pet Friendly

Las Cruces, New 4BR home, Vacation, Games, Pickleball, Family Friendly

10.0 out of 10, Exceptional, (11)
"Wonderful stay. Thank you for hosting us."
Las Cruces, New 4BR home, Vacation, Games, Pickleball, Family Friendly

Casa Sonoma | Spacious, Central Retreat | Peloton

10.0 out of 10, Exceptional, (41)
"Enjoyed our time here. Would definitely stay again. "
$252 nightly
The price is $287
Oct 27 - Oct 28
Total with taxes and fees
Casa Sonoma | Spacious, Central Retreat | Peloton

NEW!!!!! Beautifully Remodeled 5 Bedroom Mesilla Street Home- All New Furniture

10.0 out of 10, Exceptional, (11)
"We enjoy this house! Clean, well decorated, plenty of room for all of us."
NEW!!!!! Beautifully Remodeled 5 Bedroom Mesilla Street Home- All New Furniture

The Stranded Time Traveler; a timeless experience in a very convenient location!

8.6 out of 10, Excellent, (7)
"All three of us were stunned walking inside at how awesome the place looked. Very smartly laid out and very all immersive. Absolutely no problems during the stay and Host stopped by to check on us. Will absolutely stay again"
$114 nightly
The price is $131
Oct 6 - Oct 7
Total with taxes and fees
The Stranded Time Traveler; a timeless experience in a very convenient location!

Southwest Gem just minutes from White Sands National Park

10.0 out of 10, Exceptional, (17)
"Beautifully decorated, modern, and very clean place to stay! I messed up the check out times (since we were doing a cross country trips and staying at multiple Vrbos), and the hosts were very accommodating and understanding. If you need a wonderful place near White Sands where you can also bring your dog, this is it! "
$207 nightly
The price is $221
Oct 6 - Oct 7
Total with taxes and fees
Southwest Gem just minutes from White Sands National Park

Casita Azul, Mesilla Plaza Only Steps Away

10.0 out of 10, Exceptional, (175)
"Perfect place to stay during your visit to Mesilla/Las Cruces. "
Casita Azul, Mesilla Plaza Only Steps Away

Private Oasis Near Old Mesilla - Home with an In-Ground Pool!

10.0 out of 10, Exceptional, (65)
"Really enjoyed our stay in this very nice property. House was in excellent condition. Pool was fantastic. Location is very near Old Mesilla and numerous great restaurants. Would highly recommend and would stay again."
Private Oasis Near Old Mesilla - Home with an In-Ground Pool!

Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More

10.0 out of 10, Exceptional, (1)
"Perfect surroundings, loved the outside patio"
$160 nightly
The price is $173
Oct 5 - Oct 6
Total with taxes and fees
Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More

Cozy Family-Friendly 3BR2BA Home with Enclosed Backyard

8.8 out of 10, Excellent, (31)
"This home was cozy and comfortable. My family and I were attending a loved one's funeral over two days in Las Cruces and we felt very secure and close to family there. Communication with the owners was kind kind. "
$266 nightly
The price is $303
Oct 28 - Oct 29
Total with taxes and fees
Cozy Family-Friendly 3BR2BA Home with Enclosed Backyard

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

9.6 out of 10, Exceptional, (4)
"The property was great and we enjoyed our stay. I have to say that the messaging in the VRBO app dropped several messages, some I sent and apparently some sent by VRBO. That is troubling, but does not reflect on the property. "
$140 nightly
The price is $152
Oct 6 - Oct 7
Total with taxes and fees
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Dona Ana Hotel Reviews

Find out more about Dona Ana

Find out more about Dona Ana

Everything you need to know about Dona Ana vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Dona Ana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Dona Ana vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Dona Ana vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Dona Ana. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Dona Ana in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $131 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Dona Ana rentals

At Expedia, we put the best Dona Ana vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Dona Ana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Dona Ana vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Dona Ana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Dona Ana?

Yes, we have vacation rentals near well known local attractions in Dona Ana, or you can go with a more secluded option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Dona Ana has to offer?

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis: Visitors like this Dona Ana vacation home rental. It offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What can I see and do in Dona Ana?

Explore the area and family-friendly sights such as Museum of Nature & Science, or get out into nature at a spot like Dripping Springs Natural Area. Red Hawk Golf Club and Sonoma Ranch Golf Course are a couple of places you'll find in the larger area.

What are vacation rentals like in Dona Ana?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Dona Ana. Vacation rentals offer extras like WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a sanitized environment, vacation rentals can offer a sense of safety away from public hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.