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Featured La Mesa Independent Hotels

See all 1,189 Hotels in La Mesa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego
4.0 out of 5.0
4.5 out of 5 (7,495 reviews)
Fantastic Location and Service Staff! The hotel was beautiful, gorgeous views, close to everything and exceptional service staff. Everyon … - 

$127

$127
The Sofia Hotel

The Sofia Hotel

150 W Broadway, San Diego
3.5 out of 5.0
4.3 out of 5 (7,239 reviews)
It's a nice hotel though the room is very small. The room is very clean - 

$107

$107
The Horton Grand Hotel

The Horton Grand Hotel

311 Island Ave, San Diego
3.5 out of 5.0
4.2 out of 5 (3,522 reviews)
Great location. Safe area Close to everything including the harbour, gaslamp district and airport. The area was also Safe wit … - 

$80

$80
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

207 5th Ave, San Diego
4.0 out of 5.0
4.3 out of 5 (3,213 reviews)
great location Excellent hotel. Right downtown. Parked across the street for much less but highly recommend it. - 

$149

$149
Ramada San Diego North Hotel and Conference Center

Ramada San Diego North Hotel and Conference Center

5550 Kearny Mesa Rd, San Diego
3.0 out of 5.0
3.7 out of 5 (3,508 reviews)
2night stay Had a great stay at the Ramada. Great staff. Entire property including the pool was clean. Close to … - 

$72

$72
Hotel Ticuán

Hotel Ticuán

Av. Miguel Hidalgo (8va) #8190, Tijuana
3.5 out of 5.0
4.4 out of 5 (1,115 reviews)
Why I stay at the hotel Ticuán Room was nice personnel were great from the receptionist to the maids bellman and waiters . I will … - 

$72

$72
Town and Country San Diego

Town and Country San Diego

500 Hotel Cir N, San Diego
3.5 out of 5.0
3.3 out of 5 (1,582 reviews)
Good staff. Good location. But vending machine was broken. So I cannot get bottle of water near my … - 

$104

$104
Hyatt Regency La Jolla

Hyatt Regency La Jolla

3777 La Jolla Village Drive, San Diego
4.0 out of 5.0
4.3 out of 5 (2,543 reviews)
Friendly staff We had an amazing experience during our stay. The receptionist Jazmin made sure that our stay in ho … - 

$99

$99
Paradise Point Resort & Spa

Paradise Point Resort & Spa

1404 Vacation Rd, San Diego
4.0 out of 5.0
3.8 out of 5 (2,660 reviews)
A couple of things First I want to temper this review by saying that the staff are wonderful and the grounds beautiful … - 

$101

$101
California Suites Hotel

California Suites Hotel

5415 Clairemont Mesa Blvd, San Diego
2.0 out of 5.0
3.5 out of 5 (3,464 reviews)
Good It was good. It was also great. It was also excellent. It was also swell. It was also fun. - 

$64

$64
Bahia Resort Hotel

Bahia Resort Hotel

998 W Mission Bay Dr, San Diego
3.5 out of 5.0
4.1 out of 5 (4,399 reviews)
Loved every minute Beautiful clean comfortable room, kitchen a big convenience as we didn't want to search around for … - 

$99

$99
Hotel Lucerna Tijuana

Hotel Lucerna Tijuana

Paseo del los Heroes #10902, Zona Rio, Tijuana
4.0 out of 5.0
4.4 out of 5 (968 reviews)
I think it’s one of the best hotels in this town Clean room , smells good , very attentive staff , I would definitely stay here again - 

$115

$115
Hotel Palacio Azteca

Hotel Palacio Azteca

Blvd Cuauhtemoc Sur N.213, Tijuana
3.5 out of 5.0
4.0 out of 5 (1,129 reviews)
I hotel close to downtown I think warm for close to downtown good experience - 

$79

$79
Motel 6 San Diego - Hotel Circle - Mission Valley

Motel 6 San Diego - Hotel Circle - Mission Valley

2424 Hotel Circle North, San Diego
2.0 out of 5.0
3.2 out of 5 (1,084 reviews)
The hotel staff was very nice and friendly the hotel was clean but the beds were a little rough not … - 

$60

$60
The Westin San Diego

The Westin San Diego

400 W Broadway, San Diego
4.0 out of 5.0
4.2 out of 5 (3,269 reviews)
Great hotel if you have any business downtown. Close to everything including the harbor, airport an … - 

$109

$109
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd, San Diego
4.0 out of 5.0
3.9 out of 5 (3,383 reviews)
Wonderful We loved the room, the view of Mission bay was outstanding. The fact the hotel was only blocks from … - 

$123

$123
The Atwood

The Atwood

1201 Hotel Circle South, San Diego
3.0 out of 5.0
3.8 out of 5 (984 reviews)
Pleasantly surprised. Honestly didn't expect much for the rate we got but my family and I were pleasantly surprised. Room … - 

$62

$62
Red Roof Inn San Diego - Pacific Beach/SeaWorld Area

Red Roof Inn San Diego - Pacific Beach/SeaWorld Area

4545 Mission Bay Dr, San Diego
2.0 out of 5.0
3.2 out of 5 (1,070 reviews)
Price and very comfortable Is very nice, we have little be trouble with noise from up stair apartment,Mr. Jayson from overnigh … - 

$64

$64
Good Nite Inn San Diego near SeaWorld

Good Nite Inn San Diego near SeaWorld

3880 Greenwood St, San Diego
2.5 out of 5.0
3.2 out of 5 (4,871 reviews)
Rooms was clean and brand-new after renovation. Front staff was very kind and polite. But keys some … - 

$52

$52
Grand Hotel Tijuana

Grand Hotel Tijuana

Blvd. Agua Caliente #4558, Tijuana
3.5 out of 5.0
3.9 out of 5 (1,272 reviews)
Nice hotel, rooms need an upgrade. Good location, great views. - 

$91

$91
Map

Recently booked La Mesa hotels

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Independent La Mesa Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in La Mesa, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent La Mesa hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some La Mesa Independent locations may even offer extra little benefits and discounts for frequent travelers.