Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Start by selecting your hotel
Start by selecting your hotel
Start by selecting your hotel

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Los Osos Vacation Packages

Save Time and Money with Los Osos Vacation Packages

Expedia has some Los Osos travel packages ready and waiting. Combining your airfares and lodgings is one of the most straightforward ways to save cash on your trip.

Smart travelers who book a package deal on Expedia will save as much as $583*.

With more than 550 partner airlines and 750,000 properties worldwide for you to choose from on our comprehensive database, you'll be jetting off on your vacation in no time!

Almost all bookings can be changed with no added fees from us.

Places to Visit in Los Osos

We've got all the sightseeing info you require for your trip to Los Osos. Grab your planner and get ready to start filling that itinerary.

The conservation of valuable habitats and species is hugely important. Get lost in the peacefulness of nature at Morro Coast Audubon Society Sweet Springs Nature Preserve and see what animals are about. There's a wonderful range of things to do in and around this destination. The preservation and protection of native habitats and their wildlife is fundamentally important. Enjoy the serenity of nature at Los Osos Oaks State Reserve and see what animals and plants are about. Still have some time to spare? Want to wander where the WiFi signal gets weak? Have a time out from your phone, leave the world behind and go for a hike through the natural environment at Islay Creek Trail.

Los Osos Accommodations

While it can be hard to find accommodations in the center of Los Osos, there are no less than 30 places to stay in the nearby areas. Organizing luxury getaways and cheap vacations is easy with Expedia.

Need help looking for a soft bed to snuggle up in at night? Our top suggestions are the Estero Inn (501 Embarcadero) and the Back Bay Inn (1391 Second Street).

Nearest Airports to Los Osos

Catching a flight to San Luis Obispo County Regional Airport (SBP)? It's located 11 miles (18 km) east of the center of this neighborhood. Time to collect your bags and get your trip to Los Osos started!

*Savings based on all vacation package bookings with Flight + Hotel on Expedia.com from January through December 2017, as compared to price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.


Top Deals on Flights

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.