Find hotels near Medical Center, Guatemala City from $70

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Compare 567 hotels close to Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Outdoor pool
Hyatt Centric Guatemala City

Hyatt Centric Guatemala City

4.5 star property
Zona 10, 0.8 mi from Medical Center
9.6 out of 10, Exceptional, (780)
"the hotel is perfectly located. The staff is happy, courteous, helpful. Food is good. Great Breakfast Buffett, good room service. We will return every time we go back to Guatemala City."
United States
Fernando
$134 nightly
The price is $164
Dec 22 - Dec 23
Total with taxes and fees
Hyatt Centric Guatemala City
Front of property
Apart - Hotel Casa Serena

Apart - Hotel Casa Serena

4.0 star property
Zona 10, 0.9 mi from Medical Center
9.6 out of 10, Exceptional, (97)
"Love this place, I stayed twice and will do it again!"
United States
Maritza
$99 nightly
The price is $122
Jan 1 - Jan 2, 2026
Total with taxes and fees
Apart - Hotel Casa Serena
Standard Single Room, 1 Queen Bed, Courtyard View | Garden view
Casa Carmel Bed and Breakfast

Casa Carmel Bed and Breakfast

3.0 star property
Guatemala City Historical District, 1.8 mi from Medical Center
9.6 out of 10, Exceptional, (112)
"Casa Carmel was the perfect place to spend a tranquil evening before embarking on a grueling travel itinerary. Would highly recommend."
United States
Eric
$58 nightly
The price is $70
Dec 8 - Dec 9
Total with taxes and fees
Casa Carmel Bed and Breakfast
Exterior
Good Hotel Guatemala City

Good Hotel Guatemala City

3.0 star property
Zona 4, 0.6 mi from Medical Center
9.4 out of 10, Exceptional, (237)
"Great place to stay in the city"
United States
Cesar
$103 nightly
The price is $126
Dec 6 - Dec 7
Total with taxes and fees
Good Hotel Guatemala City
Exterior
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4.0 star property
Zona 10, 0.8 mi from Medical Center
9.2 out of 10, Wonderful, (1606)
"Location and hotel is amazing and the staff is very helpful"
United States
Martha
$88 nightly
The price is $107
Jan 1 - Jan 2, 2026
Total with taxes and fees
Wyndham Garden Guatemala City
Interior entrance
Hotel Ciudad Vieja

Hotel Ciudad Vieja

3.0 star property
Zona 10, 0.4 mi from Medical Center
9.2 out of 10, Wonderful, (219)
"Room was big, clean bathroom, helpful staff, fresh adequate breakfast, good location, close to the airport, in zona 10, a relatively safe areas for tourists. All in all a great stay "
United Kingdom
Deepti
$77 nightly
The price is $94
Dec 6 - Dec 7
Total with taxes and fees
Hotel Ciudad Vieja
Reception hall
Barceló Guatemala City

Barceló Guatemala City

4.5 star property
Zona 9, 1.1 mi from Medical Center
9.2 out of 10, Wonderful, (3092)
"Barcelo is a nice, clean and comfortable place to stay"
United States
Ana
$66 nightly
The price is $81
Jan 4 - Jan 5, 2026
Total with taxes and fees
Barceló Guatemala City
Outdoor pool
Holiday Inn Guatemala City by IHG

Holiday Inn Guatemala City by IHG

3.5 star property
Zona 10, 0.8 mi from Medical Center
9.2 out of 10, Wonderful, (1000)
"Zona 10 is the best place to stay on Guatemala and the hotel is in good shape."
United States
Luciano
$75 nightly
The price is $92
Dec 25 - Dec 26
Total with taxes and fees
Holiday Inn Guatemala City by IHG
4 restaurants, breakfast, lunch, dinner served; international cuisine
InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG

5.0 star property
Zona 10, 0.9 mi from Medical Center
9.2 out of 10, Wonderful, (1000)
"Very friendly staff and clean room"
United States
Julia
$145 nightly
The price is $177
Dec 22 - Dec 23
Total with taxes and fees
InterContinental Real Guatemala by IHG
Front of property
La Inmaculada Hotel

La Inmaculada Hotel

3.5 star property
Zona 10, 0.9 mi from Medical Center
9.2 out of 10, Wonderful, (609)
"Everything was perfect, the room was perfectly cleaned every day, the restaurant is amazing, the people that wirks there amazing!!"
United States
Claudia
$90 nightly
The price is $110
Dec 6 - Dec 7
Total with taxes and fees
La Inmaculada Hotel
Exterior
Dai Nonni Hotel

Dai Nonni Hotel

3.0 star property
Zona 13, 1.5 mi from Medical Center
9.2 out of 10, Wonderful, (335)
"Great staff and amazing internet!!! Perfect to move to and from the airport!"
Spain
Lina
$63 nightly
The price is $77
Dec 30 - Dec 31
Total with taxes and fees
Dai Nonni Hotel
Outdoor pool
Hotel San Carlos

Hotel San Carlos

3.5 star property
Zona 10, 0.5 mi from Medical Center
9.0 out of 10, Wonderful, (445)
"Clean room. Wonderful staff"
United States
Cynthia
$87 nightly
The price is $106
Dec 27 - Dec 28
Total with taxes and fees
Hotel San Carlos
Breakfast, lunch, dinner served; international cuisine, garden views
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4.0 star property
Zona 10, 0.9 mi from Medical Center
9.0 out of 10, Wonderful, (1003)
"My stay at this place was excellent "
United States
Diego
$101 nightly
The price is $123
Dec 25 - Dec 26
Total with taxes and fees
Clarion Suites Guatemala City
Exterior
Courtyard by Marriott Guatemala City

Courtyard by Marriott Guatemala City

3.5 star property
Zona 10, 0.8 mi from Medical Center
9.0 out of 10, Wonderful, (542)
"Everything about this hotel was perfection"
United States
Thorne
$93 nightly
The price is $113
Dec 24 - Dec 25
Total with taxes and fees
Courtyard by Marriott Guatemala City
Exterior
Meraki Boutique Hotel

Meraki Boutique Hotel

3.5 star property
Zona 10, 0.8 mi from Medical Center
9.0 out of 10, Wonderful, (393)
"Very comfortable room and great location. "
United States
Elmer
$81 nightly
The price is $99
Jan 1 - Jan 2, 2026
Total with taxes and fees
Meraki Boutique Hotel
Loft, Kitchen, City View | Private kitchen | Full-size fridge, microwave, stovetop, dishwasher
Hotel Fontabella

Hotel Fontabella

4.0 star property
Zona 10, 0.7 mi from Medical Center
9.0 out of 10, Wonderful, (174)
"Clean room, friendly and helpful staff and great amenities "
United States
Jaewon
$97 nightly
The price is $118
Dec 10 - Dec 11
Total with taxes and fees
Hotel Fontabella
Front of property - evening/night
Ever Green Hotel

Ever Green Hotel

3.5 star property
Zona 10, 1.2 mi from Medical Center
9.0 out of 10, Wonderful, (60)
"Extremely friendly and helpful staff. "
United States
M Lynn
$76 nightly
The price is $94
Dec 5 - Dec 6
Total with taxes and fees
Ever Green Hotel
Dining
Suites Terraza Imperial

Suites Terraza Imperial

3.0 star property
Zona 13, 1.4 mi from Medical Center
9.0 out of 10, Wonderful, (299)
"Clean room ,excellent location,laundry.parking staff excellent."
United States
Sergio
$73 nightly
The price is $88
Jan 1 - Jan 2, 2026
Total with taxes and fees
Suites Terraza Imperial
Exterior
Cayalá Lofts

Cayalá Lofts

3.5 star property
Zona 16, 1.6 mi from Medical Center
9.0 out of 10, Wonderful, (61)
"Everything is perfect staff they’re very nice specially with the check in they’re very helpful I’ll recommend it "
United States
MIRTA
$90 nightly
The price is $107
Dec 5 - Dec 6
Total with taxes and fees
Cayalá Lofts
Exterior
Hotel Casa Veranda

Hotel Casa Veranda

3.5 star property
Zona 10, 0.8 mi from Medical Center
8.8 out of 10, Excellent, (1003)
"Room very clean, and the staff was nice! "
United States
Jose
$80 nightly
The price is $97
Dec 28 - Dec 29
Total with taxes and fees
Hotel Casa Veranda
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Medical Center Hotel Reviews

Barceló Guatemala City

Barceló Guatemala City

10/10 Excellent
"Las comodidades e higiene impecable "
RAUL 2-night trip
Posted 1 day ago
Barceló Guatemala City

Hotels near other Medical Center attractions

Botanical Garden

Explore the great outdoors at Botanical Garden, a lovely green space in Guatemala City. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

Ixchel Museum

You can spend an afternoon exploring the galleries in Ixchel Museum during your travels in Guatemala City. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Medical Center?
Medical Center is located in Guatemala City. This welcoming area is known for its array of dining options. If you're looking for a convenient place to stay, check out the 145 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Medical Center?
Wyndham Garden Guatemala City is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.8 mi (1.3 km) from Medical Center. Other good choices close by include Hotel Casa Veranda and Clarion Suites Guatemala City.
How many hotels can I expect to find near Medical Center?
Expedia has 145 hotels and other accommodations within a mile from Medical Center.
If I need to cancel the hotel reservation for my stay near Medical Center, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to get the best deals available near Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Medical Center?
For more information about picking new dates or cancelling your stay near Medical Center, go to https://www.expedia.com/service/.
What can I see and do near Medical Center?
Ixchel Museum, Popol Vuh Museum, and Museo de Ferrocarril feature a variety of fascinating exhibits to see while you're in town. Palacio Nacional de la Cultura, Kaminaljuyu, and Cerrito del Carmen are monuments to see when you're exploring the area around Medical Center. Spend some time wandering around Constitution Square, Botanical Garden, and Kanajuyú Ecological Park.