Barrio de Santiago

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
Study a collection of 19th-century images of jungle-covered ancient ruins, which provided historians with a wealth of knowledge about the Mayans.
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Things to do

Turibus Panoramic Sightseeing Tour of Merida

Merida: Panoramic Sightseeing Bus Tour Ticket with 2 routes.

$9
per adult
74% of travellers recommend
Merida: Panoramic Sightseeing Bus Tour Ticket with 2 routes.
Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

$79
per adult
94% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

$9
per adult
84% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
Cenote Yuum Kimil

4 Cenotes Tour in Homún all inclusive from Merida

$78
per adult
94% of travellers recommend
4 Cenotes Tour in Homún all inclusive from Merida
Celestún Flamingos and Beach Tour, departing from Mérida

Celestún Flamingos and Beach Sightseeing Tour Departing from Mérida

$65
per adult
Celestún Flamingos and Beach Sightseeing Tour Departing from Mérida
Kabah

Tour to Uxmal Kabah and Chocolate Museum from Mérida

$74
per adult
100% of travellers recommend
Tour to Uxmal Kabah and Chocolate Museum from Mérida
See all activities in Mérida

Barrio de Santiago Hotel Deals

Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
$43 nightly
The price is $52 total per night from Dec 1 to Dec 2
$52 total
Dec 1 - Dec 2
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Casa 57
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
$47 nightly
The price is $56 total per night from Nov 29 to Nov 30
$56 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this boutique hotel in Mérida. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (43 reviews)
"Everything was great!"

Reviewed on Nov 3, 2026

Casa Aura Hotel, Mérida
Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
$175 nightly
The price is $211 total per night from Nov 29 to Nov 30
$211 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this luxury hotel in Mérida. Enjoy free WiFi, free parking, and room service. Popular attractions Plaza Grande and Paseo de Montejo are located ...
9.8/10 Exceptional! (182 reviews)
"The hotel has been renovated wonderfully. We stayed in a king-bed suite and enjoyed it. The staff is very attentive and bilingual, which makes communication easy. The hotel is located about 5 minutes from downtown. So if you are looking for some peace, this is it. We used Uber to get around, and ..."

Reviewed on Nov 6, 2026

Casa Loreto 1893
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
$42 nightly
The price is $48 total per night from Nov 22 to Nov 23
$48 total
Nov 22 - Nov 23
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Ambassador Merida
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
$81 nightly
The price is $97 total per night from Dec 1 to Dec 2
$97 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this spa hotel in Mérida. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (473 reviews)
"Staff is wonderful."

Reviewed on Oct 26, 2026

Hotel Unknown
Casona 61 Boutique Hotel

Casona 61 Boutique Hotel

3.5 out of 5
Calle 61 entre 66 y 68 Mérida YUC
$45 nightly
The price is $55 total per night from Dec 8 to Dec 9
$55 total
Dec 8 - Dec 9
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (437 reviews)
"First I would like to say that the staff is amazing and I really wish I could give more stars to the hotel, but it was terrible how our room kept running out of water, every day multiple times per day we had to ask for water to shower, flush the toilet and wash our hands. It could definitely improve ..."

Reviewed on Nov 7, 2026

Casona 61 Boutique Hotel
See all 1,378 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Barrio de Santiago
Learn more about Barrio de Santiago
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Plaza Grande or Paseo 60.

A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

A long pier extending into the ocean with clear turquoise water and a clear blue sky.

Chelem

You might make a stop by Chelem Park while you're exploring Chelem.

A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travelers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

A meal with tacos, a salad, and a drink at a restaurant.
Photo by Alba and John
Open Photo by Alba and John

Santa Lucia

While there might not be top attractions in Santa Lucia, you can explore the larger area and discover places like Plaza Grande and Paseo 60.

Barrio de Santiago

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