Barrio de Santiago

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
Study a collection of 19th-century images of jungle-covered ancient ruins, which provided historians with a wealth of knowledge about the Mayans.
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Things to do

Turibus Panoramic Sightseeing Tour of Merida

Merida: Panoramic Sightseeing Bus Tour

$10
per adult
74% of travellers recommend
Merida: Panoramic Sightseeing Bus Tour
Cenote Yuum Kimil

4 Cenotes Tour in Homún all inclusive from Merida

$75
per adult
94% of travellers recommend
4 Cenotes Tour in Homún all inclusive from Merida
Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

$79
per adult
90% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

$10
per adult
80% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
Chichen Pueblos Magicos, Izamal + Valladolid Day Trip

Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included

$119
per adult
92% of travellers recommend
Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included
Tour Hacienda and Cenotes Mucuyché with Guided Tour in Oxkintok

Tour Hacienda and Cenotes Mucuyché with Guided Tour in Oxkintok

$92
per adult
Tour Hacienda and Cenotes Mucuyché with Guided Tour in Oxkintok
See all activities in Mérida

Barrio de Santiago Hotel Deals

Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
$35 nightly
The price is $42 total per night from Oct 11 to Oct 12
$42 total
Oct 11 - Oct 12
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (436 reviews)
"Everything was great during my entire stay"

Reviewed on Aug 14, 2026

Hotel Casa 57
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
$81 nightly
The price is $98 total per night from Nov 8 to Nov 9
$98 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this spa hotel in Mérida. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (464 reviews)
"Loved the small private pool and the room was very clean."

Reviewed on Oct 5, 2026

Hotel Unknown
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
$29 nightly
The price is $35 total per night from Oct 17 to Oct 18
$35 total
Oct 17 - Oct 18
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Ambassador Merida
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
$38 nightly
The price is $46 total per night from Oct 12 to Oct 13
$46 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this boutique hotel in Mérida. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
Casa Aura Hotel, Mérida
Casona 61 Boutique Hotel

Casona 61 Boutique Hotel

3.5 out of 5
Calle 61 entre 66 y 68 Mérida YUC
$42 nightly
The price is $51 total per night from Oct 21 to Oct 22
$51 total
Oct 21 - Oct 22
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (422 reviews)
"Staff were incredible and the breakfast was huge and tasted amazing"

Reviewed on Oct 7, 2026

Casona 61 Boutique Hotel
Hotel Boutique La Casona By Kavia

Hotel Boutique La Casona By Kavia

3.5 out of 5
532 Calle 59 Centro Mérida YUC
$45 nightly
The price is $55 total per night from Oct 19 to Oct 20
$55 total
Oct 19 - Oct 20
Total with taxes and fees
Stay at this hotel in Mérida. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Boutique La Casona By Kavia
See all 1,386 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Barrio de Santiago
Learn more about Barrio de Santiago
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Plaza Grande or Paseo 60.

A sunset over a body of water with a rocky shoreline.
Photo by Tony Lozano
Open Photo by Tony Lozano

Chelem

You might make a stop by Chelem Park while you're exploring Chelem.

A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travelers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

A meal with tacos, a salad, and a drink at a restaurant.
Photo by Alba and John
Open Photo by Alba and John

Santa Lucia

While there might not be top attractions in Santa Lucia, you can explore the larger area and discover places like Plaza Grande and Paseo 60.

Barrio de Santiago

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