Little Italy Vacations from $379

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Your Little Italy Vacation

Get lost in the magic of this trendy neighborhood with a Little Italy vacation package. From its shopping and cafes to its dining, there's lots here for everyone. Not sure what to do during your trip to Little Italy? Nearby attractions like San Diego Zoo, Balboa Park and Petco Park are good places to start. Expedia will help put your plans into action. Book your perfect Little Italy vacation today.

The Latest Little Italy Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Riviera Oaks Resort
Hyatt Vacation Club at The Welk, San Diego Area
Pala Casino Spa And Resort
The Arthur
Barsala City Villas

Where to stay in Little Italy

Find the best Little Italy areas and neighborhoods for the activities you enjoy most. Learn more about Little Italy

Little Italy Hotel Deals

The Little Italy Hotel Downtown San Diego
The Little Italy Hotel Downtown San Diego
4 out of 5
1646 Front St, San Diego, CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $135 total per night from Jul 6 to Jul 7
$135 total
Jul 6 - Jul 7
Total includes taxes and fees
7.8/10 Good! (1,001 reviews)
"All good"

Reviewed on Jun 28, 2025

The Little Italy Hotel Downtown San Diego
La Pensione Hotel
La Pensione Hotel
3 out of 5
606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $181 total per night from Jul 7 to Jul 8
$181 total
Jul 7 - Jul 8
Total includes taxes and fees
8.4/10 Very Good! (1,770 reviews)
"Best location in Little Italy! Loved all the nooks and crannies the hotel had too. Lots of character!"

Reviewed on Jun 30, 2025

La Pensione Hotel
Little Italy Inn - Limited Service Apart Hotel
Little Italy Inn - Limited Service Apart Hotel
2.5 out of 5
1736 State St, San Diego, CA
$148 nightly
The price is $168 total per night from Jul 28 to Jul 29
$168 total
Jul 28 - Jul 29
Total includes taxes and fees
8.2/10 Very Good! (9 reviews)
"This was the first time staying in Little Italy and I enjoyed the experience. The place, including the kitchen was spotless. I enjoyed being able to cook my own meals 😁"

Reviewed on Jun 21, 2025

Little Italy Inn - Limited Service Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Little Italy

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.