Find all hotels by Independent in Otay Mesa West, CA from $63
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Our top choices for Otay Mesa West Independent
9.2 out of 10, Wonderful, (3178)
"Great stay and location!"
Jason
$139 nightly
The price is $160
Dec 12 - Dec 13
Total with taxes and fees
9.2 out of 10, Wonderful, (2941)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
Eric
$152 nightly
The price is $175
Dec 14 - Dec 15
Total with taxes and fees
9.4 out of 10, Exceptional, (1325)
"My wife loved everything about this vintage hotel."
Eddie
$226 nightly
The price is $259
Dec 15 - Dec 16
Total with taxes and fees
Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp QuarterDowntown San Diego
9.0 out of 10, Wonderful, (1161)
"Amenities and location were great.
"
Julie
$192 nightly
The price is $223
Dec 25 - Dec 26
Total with taxes and fees
7.4 out of 10, Good, (1157)
"Clean room, great location "
Benjamin
$55 nightly
The price is $63
Dec 31 - Jan 1, 2026
Total with taxes and fees
8.6 out of 10, Excellent, (2349)
"Great stay, top tier service and excellent customer care "
Meriem
$175 nightly
The price is $202
Dec 15 - Dec 16
Total with taxes and fees
9.0 out of 10, Wonderful, (3912)
"The room was spotless the bed was so comfy the Amenities were great!! The food at the restaurant very delish"
Emily
$156 nightly
The price is $180
Dec 14 - Dec 15
Total with taxes and fees
8.0 out of 10, Very Good, (1815)
"Clean and helpful staff, thank you !"
Bora
$82 nightly
The price is $95
Dec 14 - Dec 15
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Otay Mesa West Hotel Reviews
Bay Club Hotel & Marina
10/10 Excellent
Find out more about Otay Mesa West
Otay Mesa West, San Diego County Hotel Guide
Otay Mesa West is 11 miles from San Diego County's downtown.
San Diego County is home to the San Diego State University, the San Diego Zoo and the Balboa Park.
If you're in need of some caffeine to help you get through the day, Starbucks is among the best places in Otay Mesa West to enjoy a fix. Still hungry? Giant New York Pizza is also close and dishes up a good range of meals. Are you up for a drink? Cap off an enjoyable day with an icy beer or a satisfying red at Bobar Liquor.
Accommodation Options Near Otay Mesa West
For those keen on coming to Otay Mesa West, you can stay in San Ysidro, a neighborhood which is 2 miles south of the center of Otay Mesa West. Explore Expedia's San Ysidro hotels guide to find great accommodation options such as the Rodeway Inn and Quality Inn & Suites Near The Border. You could also choose to try South Bay hotels, such as the Holiday Inn Express San Diego South - Chula Vista and Holiday Inn Express San Diego South - National City. South Bay is located 3 miles to the northeast of the center of Otay Mesa West.
Check out our San Diego County hotels page for quality places to stay in Otay Mesa West and beyond. If you want to be inspired about things to see and do there, don’t miss our San Diego County vacation travel guide.
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