The Best Saint Matthews, SC Resorts from $61

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Recommended hotels in Saint Matthews

A modern interior with a dining area, seating, and a kitchen.

1. Tru by Hilton Orangeburg

Orangeburg

Allen

$110 nightly

Nov 25 - Nov 26

Total with taxes and fees

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

2. Spark by Hilton Orangeburg

Orangeburg

Connie

$89 nightly

Nov 29 - Nov 30

Total with taxes and fees

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

3. Fairfield Inn by Marriott Orangeburg

Orangeburg

Timothy

$101 nightly

Nov 16 - Nov 17

Total with taxes and fees

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

4. Hampton Inn & Suites Orangeburg

Orangeburg

sonia

$127 nightly

Nov 25 - Nov 26

Total with taxes and fees

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

5. SpringHill Suites by Marriott Orangeburg

Orangeburg

Henrietta

$109 nightly

Nov 23 - Nov 24

Total with taxes and fees

A Holiday Inn Express & Suites hotel with a prominent sign, a central entrance, and a symmetrical facade.

6. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

Jenelyn

$118 nightly

Nov 15 - Nov 16

Total with taxes and fees

A breakfast bar with pastries, fruits, and a vase with flowers.

7. Travelodge by Wyndham Orangeburg

Orangeburg

Linda

$65 nightly

Nov 12 - Nov 13

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

8. Quality Inn & Suites Orangeburg

Orangeburg

lisa

$55 nightly

Dec 6 - Dec 7

Total with taxes and fees

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

9. Super 8 by Wyndham, Orangeburg

Orangeburg

peter

$58 nightly

Nov 17 - Nov 18

Total with taxes and fees

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

10. Sleep Inn Orangeburg

Orangeburg

Dereck

$87 nightly

Dec 6 - Dec 7

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a sofa, and a table.

11. Baymont by Wyndham Orangeburg North

Orangeburg

Brandon

$55 nightly

Nov 29 - Nov 30

Total with taxes and fees

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

12. Comfort Inn & Suites Orangeburg

Orangeburg

Andrea

$101 nightly

Nov 29 - Nov 30

Total with taxes and fees

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

13. Red Roof Inn Orangeburg

Orangeburg

phyllis

$58 nightly

Nov 22 - Nov 23

Total with taxes and fees

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

14. Suburban Studios Orangeburg

Orangeburg

Michelle

$62 nightly

Nov 17 - Nov 18

Total with taxes and fees

A hotel room with a bed, bedside table, lamp, and a mirror.

15. Baymont by Wyndham Santee

Santee

Thomas

$80 nightly

Nov 12 - Nov 13

Total with taxes and fees

A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

16. Orangeburg Inn & Suites

Orangeburg

Kaili

$60 nightly

Nov 12 - Nov 13

Total with taxes and fees

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

17. Tru By Hilton Santee

Santee

Armando

$105 nightly

Nov 29 - Nov 30

Total with taxes and fees

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

18. Hampton Inn Santee-I-95

Santee

sandra

$123 nightly

Nov 25 - Nov 26

Total with taxes and fees

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

19. Fairfield Inn & Suites by Marriott Santee

Santee

Victor

$125 nightly

Nov 17 - Nov 18

Total with taxes and fees

A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

20. Quality Inn & Suites Santee I-95

Santee

Louis

$59 nightly

Dec 2 - Dec 3

Total with taxes and fees

View all properties

Learn more about Saint Matthews

Discover small-town charm at the Calhoun County Museum, where local history comes alive through fascinating exhibits. Enjoy peaceful picnics at the town park or visit nearby Congaree National Park for remarkable hiking trails through ancient bottomland hardwood forest.

See all hotels in Saint Matthews

A swamp with tall trees and water reflecting the greenery.

Top reviews in Saint Matthews

Hampton Inn & Suites Orangeburg

Orangeburg

10/10 Excellent

Kevin

Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

10/10 Excellent

Deborah

Fairfield Inn by Marriott Orangeburg

Orangeburg

10/10 Excellent

Barry

Fairfield Inn & Suites by Marriott Santee

Santee

10/10 Excellent

Choose this hotel for a pet-friendly stop-over on our drive to Florida and had a great experience. This staff was super-friendly and this nearly-brand-new property was immaculate. They have us a great 1st floor room with easy access to the walking and parking area. We took advantage of the patio to have dinner (take-out from a local restaurant) and breakfast with our dog. The breakfast was excellent, including hot omelets, eggs, and sausage, and the 6 am start (on a Sunday) allowed us to get...

Douglas

Comfort Inn & Suites Orangeburg

Orangeburg

10/10 Excellent

Ken

Hampton Inn Santee-I-95

Santee

10/10 Excellent

Michael

Tru By Hilton Santee

Santee

10/10 Excellent

Rebecca

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

Hotel Trundle

Downtown Columbia

10/10 Excellent

Loretta

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

10/10 Excellent

Savannah

A hotel room with a bed, desk, chair, television, and a painting on the wall.

Best Western Plus Santee Inn

Santee

10/10 Excellent

Richard

A modern bar area with a central island, bar stools, and a television.

Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

10/10 Excellent

Carla

A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.

Tru By Hilton Columbia Downtown

Downtown Columbia

10/10 Excellent

Hynrie Emerlou

A two-story brick house with a porch, a flag, and a well-maintained lawn.

Graduate by Hilton Columbia SC

Downtown Columbia

10/10 Excellent

Virginia

Frequently Asked Questions

What is Saint Matthews like for a resort vacation?

You deserve to get away, and a resort is the ideal place to find all the services and amenities you need for a relaxing trip to Saint Matthews. One of the comfortable resort hotels in the area could be just what you're searching for, whether you're hoping for a luxurious suite, a state-of-the-art fitness center, or activities for the kids.

What can I do in Saint Matthews?

Congaree National Park, South Carolina State University, and Claflin University are a few interesting places to visit nearby. Additional attractions in the area include Santee State Park and Harry Hampton Visitor Center.

What's the seasonal weather like in Saint Matthews?

The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Saint Matthews is 51 inches.

What's the best way to get to and around Saint Matthews?

Fly into Columbia Metropolitan Airport (CAE), which is located 27.9 mi (44.8 km) from the heart of the city. If you'd like to explore around the area, consider renting a car to take in more sights.

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Things to do in South Carolina
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Best Resorts in Saint Matthews

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Recommended hotels in Saint Matthews

1. Tru by Hilton Orangeburg

2. Spark by Hilton Orangeburg

3. Fairfield Inn by Marriott Orangeburg

4. Hampton Inn & Suites Orangeburg

5. SpringHill Suites by Marriott Orangeburg

6. Holiday Inn Express & Suites Orangeburg by IHG

7. Travelodge by Wyndham Orangeburg

8. Quality Inn & Suites Orangeburg

9. Super 8 by Wyndham, Orangeburg

10. Sleep Inn Orangeburg

11. Baymont by Wyndham Orangeburg North

12. Comfort Inn & Suites Orangeburg

13. Red Roof Inn Orangeburg

14. Suburban Studios Orangeburg

15. Baymont by Wyndham Santee

16. Orangeburg Inn & Suites

17. Tru By Hilton Santee

18. Hampton Inn Santee-I-95

19. Fairfield Inn & Suites by Marriott Santee

20. Quality Inn & Suites Santee I-95

Learn more about Saint Matthews

Top reviews in Saint Matthews

Hampton Inn & Suites Orangeburg

10/10 Excellent

Frequently Asked Questions

What is Saint Matthews like for a resort vacation?

What can I do in Saint Matthews?

What's the seasonal weather like in Saint Matthews?

What's the best way to get to and around Saint Matthews?

Explore a world of travel with Expedia