San Lorenzo Vacations from $983

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Your San Lorenzo Vacation

Lock in a vacation package to San Lorenzo and immerse yourself in everything this inner city neighborhood has to offer. With a reputation for bars and pubs, markets and cafes, your next unforgettable adventure can be found right here. Your trip to San Lorenzo wouldn't be complete without stopping by big-name attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your travel plans or budget.

The Latest San Lorenzo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

Historic Centre of Florence
$983
per person
Nov 16 - Nov 21
found 20 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (588 reviews)
All the staff were amazing and helpful! The kitchen staff for breakfast catered for all out needs. The spa was excellent too and I’d highly recommended this hotel to anyone. It’s in a Great location with good links to the airport and tourist spots across the city.

Reviewed on Aug 29, 2026

Aurum Firenze

Aurum Firenze

Historic Centre of Florence
$1,040
per person
Oct 26 - Nov 1
found 12 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
The room was clean, staff reasonably friendly, breakfast breads were stale, air conditioning worked well. Conveniently located for train station

Reviewed on Sep 2, 2026

Villa Cora

Villa Cora

Oltrarno
Save 100% on your flight
$5,499
per person
Oct 8 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.8/10 Exceptional! (482 reviews)
Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

Historic Centre of Florence
$2,179
per person
Oct 8 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9/10 Wonderful! (1,010 reviews)
We had a great stay. The staff was super helpful in answering questions and providing recommendations. The rooms were very nicely sized and had great bathrooms. Perfectly located!!

Reviewed on Sep 2, 2026

Il Rivalta - Place of Charme

Il Rivalta - Place of Charme

Historic Centre of Florence
$1,702
per person
Oct 26 - Nov 1
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (600 reviews)
Amazing hotel, great for families, beautiful amenities. 12/10 recommend. The staff were amazing and very helpful and hospitable.

Reviewed on Sep 2, 2026

Where to stay in San Lorenzo

Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

A historic building with ornate carvings and statues, featuring large wooden doors and steps leading up to it.

Duomo

Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.

A stone bridge with green shutters over a river.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

A bustling European square with historic buildings, shops, and a prominent clock tower.

Santa Croce

One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.

San Lorenzo Hotel Deals

Plus Florence - Hostel

Plus Florence - Hostel

Via Santa Caterina D'Alessandria, 15 Florence FI
Fully refundableReserve now, pay when you stay
$107 nightly
$127 total
Sep 4 - Sep 5
Total with taxes and fees
8.6/10 Excellent! (1,003 reviews)
"Such a fun hostel, great pool area, rooftop and clean amenities."

Reviewed on Sep 1, 2026

Plus Florence - Hostel
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$170 nightly
$203 total
Sep 6 - Sep 7
Total with taxes and fees
The Social Hub Florence Lavagnini
IQ Hotel Firenze

IQ Hotel Firenze

Via Camillo Cavour, 88 Florence FI
$271 nightly
$314 total
Sep 19 - Sep 20
Total with taxes and fees
IQ Hotel Firenze
See all 776 properties in San Lorenzo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Lorenzo attractions

A market with various stalls selling food and drinks.

Central Market

9.0/10 (2,334 reviews)
Feast on Italian cheeses, chocolates and authentic pizza and shop for leather goods at this indoor market and its surrounding street stalls.
See properties
Piazza San Marco in Venice, featuring the Doge's Palace, St. Mark's Basilica, and the Campanile di San Marco.

Piazza San Marco

9.2/10 (91 reviews)
Piazza San Marco is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
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A street with a prominent dome building in the background.

Medici Chapels

8.8/10 (194 reviews)
Generations of Medici dukes, princes and popes were laid to rest in a series of lavish chapels and crypts in the Church of San Lorenzo.
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A historic building with classical architecture, including columns and statues, under a clear blue sky.

San Marco Convent and Museum

8.8/10 (3 reviews)
You can study the exhibits at San Marco Convent and Museum, a museum with a story of its own, during your trip to Florence. Add the area's churches or notable monuments to your travel plans.
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University of Florence

8.8/10 (16 reviews)
Enjoy the collegiate vibe at University of Florence during your visit to Florence. Experience the area's acclaimed art scene and fascinating museums.
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Russian Orthodox Church of the Nativity

10.0/10 (3 reviews)
You can learn about the history of Florence with a trip to Russian Orthodox Church of the Nativity. Discover the area's fascinating museums and churches.
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Florence Museum of Natural History

You can study the exhibits at Florence Museum of Natural History, a museum with a storied past, during your trip to Florence. Discover the area's acclaimed art scene and churches.
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Riccardian Library

After visiting Riccardian Library, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
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Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

$29
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

$19
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

$45
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
See all activities in Florence

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.