San Lorenzo Vacations from $1,070
Book a Hotel + Flight or Car together to unlock savings
Your San Lorenzo Vacation
Lock in a vacation package to San Lorenzo and immerse yourself in everything this inner city neighborhood has to offer. With a reputation for bars and pubs, markets and cafes, your next unforgettable adventure can be found right here. Your trip to San Lorenzo wouldn't be complete without stopping by big-name attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your travel plans or budget.
The Latest San Lorenzo Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Eurostars Florence Boutique
Historic Centre of Florence
$1,070
per person
Dec 6 - Dec 13
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
8.6/10 Excellent! (503 reviews)
The bed was comfortable but low to the floor. The shower was very slippery and could have used a shower mat. The breakfast was great. The staff were very nice and helpful.
Reviewed on Oct 10, 2026
c-hotels Diplomat
Historic Centre of Florence
$1,125
per person
Dec 6 - Dec 13
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
8.4/10 Very Good! (1,000 reviews)
Great location for early morning train travel! The hotel is quite nice. A little noisy from the street but we expected it due to the location so it wasn’t an issue.
Reviewed on Oct 11, 2026
Hotel Santa Maria Novella
Historic Centre of Florence
$2,194
per person
Dec 6 - Dec 13
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
9.6/10 Exceptional! (1,014 reviews)
Nice location easy to train station able to walk staff so sweet, breakfast delicious and so so clean luxury stay
Reviewed on Oct 21, 2026
Hotel L'Orologio Firenze
Historic Centre of Florence
$1,991
per person
Dec 6 - Dec 13
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
9.6/10 Exceptional! (1,000 reviews)
It gave a old school elegant feel. The rooms was very spacious and the staff was friendly and informative.
Reviewed on Oct 23, 2026
Hotel Balestri
Historic Centre of Florence
$1,694
per person
Dec 6 - Dec 13
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
9.4/10 Exceptional! (1,003 reviews)
Had a great room with access to a rooftop patio and a spectacular view
Reviewed on Oct 21, 2026
Where to stay in San Lorenzo
Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Maria Novella
Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Santa Croce
One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.
San Lorenzo Hotel Deals
Plus Florence - Hostel
Via Santa Caterina D'Alessandria, 15 Florence FI
Fully refundableReserve now, pay when you stay
$50 nightly
$64 total
Nov 24 - Nov 25
Total with taxes and fees
8.6/10 Excellent! (1,001 reviews)
"It was a good budget hotel / motel - private room - good location Excellent value for money within walking distance of most attractions and the main railway station"
Reviewed on Oct 23, 2026
The Social Hub Florence Lavagnini
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$75 nightly
$98 total
Nov 15 - Nov 16
Total with taxes and fees
9/10 Wonderful! (1,637 reviews)
"Great hotel concept. All the benefits of a 4 star hotel with a great gym and free laundry. The staff were amazing. Oh and the trolley to the nearby city center and airport is outside the front door. Loved it"
Reviewed on Oct 22, 2026
Hotel Galileo
Via Nazionale 22/A Florence FI
Fully refundableReserve now, pay when you stay
$98 nightly
$108 total
Oct 26 - Oct 27
Total with taxes and fees
9/10 Wonderful! (148 reviews)
"A very nice, clean hotel. Staff were extremely helpful!"
Reviewed on Oct 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular San Lorenzo attractions
Central Market
9.0/10 (2,334 reviews)
Feast on Italian cheeses, chocolates and authentic pizza and shop for leather goods at this indoor market and its surrounding street stalls.
Piazza San Marco
9.2/10 (91 reviews)
Piazza San Marco is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Medici Chapels
8.8/10 (194 reviews)
Generations of Medici dukes, princes and popes were laid to rest in a series of lavish chapels and crypts in the Church of San Lorenzo.
San Marco Convent and Museum
8.8/10 (3 reviews)
You can study the exhibits at San Marco Convent and Museum, a museum with a story of its own, during your trip to Florence. Add the area's churches or notable monuments to your travel plans.
University of Florence
8.8/10 (16 reviews)
Enjoy the collegiate vibe at University of Florence during your visit to Florence. Experience the area's fascinating museums and acclaimed art scene.
Saint Apollonia Last Supper
You can browse the exhibits at Saint Apollonia Last Supper, a museum with a storied past, during your travels to Florence. Experience the area's acclaimed art scene and fascinating museums.
Giardino dell'ArteCultura
10.0/10 (1 review)
Explore the great outdoors at Giardino dell'ArteCultura, a lovely green space in Florence. Visit the area's notable monuments or amble around its riverfront.
Florence Museum of Natural History
You can study the exhibits at Florence Museum of Natural History, a museum with a storied past, during your trip to Florence. Discover the area's fascinating museums and notable monuments.
Things to do
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
$20
per adult
94% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
$26
per adult
74% of travellers recommend
Accademia timed-entry Ticket with App Guide
$44
per adult
90% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.