Santa Clara Vacation Rentals

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Dec 2 - Dec 3
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Dec 12 - Dec 14

Vacation Rentals in Santa Clara

50-inch LED TV with satellite channels
Arcadia Condo Suites

Aparthotel in Costa del Este

2.5 star property
9.4 out of 10, Exceptional, (149)
"Wonderful place great staff "
United States
Shantia
$114 nightly
The price is $125
Dec 16 - Dec 17
Total with taxes and fees
Arcadia Condo Suites
Interior
LILIA HOUSE 10 MINUTES AIRPORT

Vacation Home in Panamá

$78 nightly
The price is $78
Dec 5 - Dec 6
Total with taxes and fees
LILIA HOUSE 10 MINUTES AIRPORT
Outdoor pool
Boutique Apartments Panama

Apartment in Bella Vista

3.5 star property
7.8 out of 10, Good, (209)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
$135 nightly
The price is $148
Dec 3 - Dec 4
Total with taxes and fees
Boutique Apartments Panama
Smart TV
Lodging cerro viento, 2 bedroom apartment with air conditioning.

Apartment in Cerro Viento

10.0 out of 10, Exceptional, (1)
"Tiene todo lo necesario en perfectas condiciones."
Mexico
GLADYS
$82 nightly
The price is $85
Dec 3 - Dec 4
Total with taxes and fees
Lodging cerro viento, 2 bedroom apartment with air conditioning.
Apartment, 1 Bedroom, Balcony | Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Apartment in Las Mañanitas

2.0 star property
$69 nightly
The price is $75
Dec 7 - Dec 8
Total with taxes and fees
Swette Love 10 Minutes From the Airport Tocumen
Private beach
Habitación Privada en Playa Dorada + Kitchenette

Villa in Vacamonte

3.0 star property
$33 nightly
The price is $36
Dec 3 - Dec 4
Total with taxes and fees
Habitación Privada en Playa Dorada + Kitchenette
Outdoor pool
Boutique Apartments Atlapa

Apartment in San Francisco

3.0 star property
7.8 out of 10, Good, (25)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
$129 nightly
The price is $141
Dec 4 - Dec 5
Total with taxes and fees
Boutique Apartments Atlapa
Outdoor pool
Boutique Apartments Panamá Coco del Mar

Apartment in San Francisco

3.5 star property
7.4 out of 10, Good, (150)
"Clean room good place to stay "
United States
Gideon
$180 nightly
The price is $197
Dec 3 - Dec 4
Total with taxes and fees
Boutique Apartments Panamá Coco del Mar
Lobby sitting area
San Francisco by Wynwood House

Apartment in San Francisco

3.0 star property
9.2 out of 10, Wonderful, (53)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
$125 nightly
The price is $135
Dec 12 - Dec 13
Total with taxes and fees
San Francisco by Wynwood House
Superior Double Room | Terrace/patio
La Isabela Suites

Aparthotel in Casco Viejo

3.5 star property
10.0 out of 10, Exceptional, (165)
"The room was spotless, the location perfect, and the staff was absolutely superb!"
United States
Gregory
La Isabela Suites
Deluxe Apartment | Terrace/patio
Yoo Panamá by Boutique Apartments

Apartment in Bella Vista

3.5 star property
8.0 out of 10, Very Good, (47)
"Great location but not enough towels in the room "
United States
Damion
$207 nightly
The price is $213
Dec 3 - Dec 4
Total with taxes and fees
Yoo Panamá by Boutique Apartments
Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels
Casa Lefevre By Wynwood House

Apartment in Casco Viejo

3.5 star property
8.8 out of 10, Excellent, (3)
"Once I remembered the email about access to the hotel it was all great from then on. A great surprise when I opened the door and saw this huge open space room. I loved it. "
United States
Jeff
$132 nightly
The price is $145
Dec 3 - Dec 4
Total with taxes and fees
Casa Lefevre By Wynwood House
Property grounds
Panama View House – A Hilltop Retreat with Stunning Canal Views

Vacation Home in Panama City

$96 nightly
The price is $96
Dec 3 - Dec 4
Total with taxes and fees
Panama View House – A Hilltop Retreat with Stunning Canal Views
Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated
Las Clementinas

Aparthotel in Casco Viejo

3.5 star property
9.4 out of 10, Exceptional, (169)
"Our stay at Las Clementinas was amazing. The ambiance, decor, and central location to all things in Casco Viejo made our trip magical. Not only was the hotel beautiful, the staff was incredibly warm, helpful and welcoming. The restaurant in the hotel was absolutely delicious. I would stay here ten times over. "
United States
Amanda
$128 nightly
The price is $141
Dec 4 - Dec 5
Total with taxes and fees
Las Clementinas
Apartment, 3 Bedrooms, Accessible, Pool View | Children's area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Apartment in José Domingo Espinar

2.0 star property
$71 nightly
The price is $78
Dec 12 - Dec 13
Total with taxes and fees
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Pool
Furnished 1 bedroom w City Views

Condo in Costa del Este

2.0 star property
$193 nightly
The price is $209
Dec 9 - Dec 10
Total with taxes and fees
Furnished 1 bedroom w City Views
Outdoor pool
Living 73 Panamá by Boutique Apartments

Apartment in San Francisco

3.0 star property
$235 nightly
The price is $281
Dec 22 - Dec 23
Total with taxes and fees
Living 73 Panamá by Boutique Apartments
Standard Apartment | Living area | Flat-screen TV
Torres de Alba Hotel & Suites

Aparthotel in Bella Vista

3.5 star property
8.8 out of 10, Excellent, (481)
"Good location, quick walk to the subway."
United States
Lynden
$92 nightly
The price is $102
Dec 3 - Dec 4
Total with taxes and fees
Torres de Alba Hotel & Suites
An infinity pool
Beutiful Apartment, High Speed Internet, Excellent Location

Apartment in San Francisco

8.8 out of 10, Excellent, (11)
"Easy to get to as long as there is no traffic I’d book again. "
United States
Anonymous traveler
$139 nightly
The price is $139
Dec 3 - Dec 4
Total with taxes and fees
Beutiful Apartment, High Speed Internet, Excellent Location
Apartment (3G) | Balcony
La Cuadra by Wynwood House

Condo in El Chorrillo

3.5 star property
9.2 out of 10, Wonderful, (43)
"Nice place!"
United States
Tesha
$113 nightly
The price is $122
Dec 3 - Dec 4
Total with taxes and fees
La Cuadra by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Staff was excellent, very nice room , amenities were great, location was perfect "
Robert 4-night trip
Posted 23 hours ago
JW Marriott Panama

Find out more about Santa Clara

Everything you need to know about Santa Clara vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Clara vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Clara vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Clara vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Clara. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Clara in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $91 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Clara rentals

At Expedia, we put the best Santa Clara vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Clara rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Clara vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Clara. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Santa Clara?

Yes, there are vacation rentals close to popular attractions in Santa Clara, or you can choose a secluded option if you'd like a relaxing place to stay. Santa Clara is known for its monuments.

What are some of the best vacation home rentals that Santa Clara has to offer?

Panama View House – A Hilltop Retreat with Stunning Canal Views: This vacation home rental outside of Santa Clara has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the larger area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are vacation rentals like in Santa Clara?

Vacation rentals are privately owned properties you can book for several days or longer in Santa Clara. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.