Santa Clara Vacation Rentals from $69: Search Short-Term Rentals

Q: What are some of the best vacation home rentals that Santa Clara has to offer?

Downtown Villa with Private Pool & Bar : This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

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Our top choices for Santa Clara vacation rentals

A poolside area with white sofas, a pool, and outdoor seating.

1. La Palma Experience

Amador

Juan Luis Perez

$69 nightly

Oct 1 - Oct 2

Total with taxes and fees

A beach with rocky terrain and a distant building.

2. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Vacamonte

Cynthia

$27 nightly

Oct 17 - Oct 18

Total with taxes and fees

A modern outdoor swimming pool with a clear view of a tall building in the background.

3. Dovle Residences by HMS-Preferred Member

San Francisco

David

$155 nightly

Oct 7 - Oct 8

Total with taxes and fees

An outdoor seating area with tables and chairs, a view of the beach, and string lights.

4. Refugio Frente al Mar Vista Venao

Veracruz

Victor

$50 nightly

Oct 25 - Oct 26

Total with taxes and fees

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

5. La Isabela Suites

Casco Viejo

David

$135 nightly

Oct 8 - Oct 9

Total with taxes and fees

A rooftop pool with a city view, lounge chairs, and a clear sky.

6. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

Rame

$152 nightly

Oct 3 - Oct 4

Total with taxes and fees

A multi-story building with balconies, large windows, and a clear blue sky.

7. Las Clementinas

Casco Viejo

James

$170 nightly

Oct 13 - Oct 14

Total with taxes and fees

A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

8. Yoo Panamá by Boutique Apartments

Bella Vista

Howard

$184 nightly

Sep 30 - Oct 1

Total with taxes and fees

A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

9. Torres de Alba Hotel & Suites

Bella Vista

Robert

$92 nightly

Sep 30 - Oct 1

Total with taxes and fees

10. San Francisco by Wynwood House

San Francisco

Georg

$129 nightly

Oct 1 - Oct 2

Total with taxes and fees

A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

11. Yoo Panama Luxury Ocean View Apartment

Bella Vista

Mark

$124 nightly

Oct 15 - Oct 16

Total with taxes and fees

A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

12. Boutique Apartments Panama

Bella Vista

fitz

$141 nightly

Sep 30 - Oct 1

Total with taxes and fees

A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

13. Living 73 Panamá by Boutique Apartments

San Francisco

Lorenz

$167 nightly

Sep 30 - Oct 1

Total with taxes and fees

A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

14. Modern Apartments at The Gray Prime Location

Bella Vista

Denise

$70 nightly

Oct 7 - Oct 8

Total with taxes and fees

15. Cozy La Chorrera Villa With Private Patio & Nature Views

La Chorrera

$49 nightly

Oct 23 - Oct 24

Total with taxes and fees

16. w* | Classy 1BR in San Francisco w/ Pool

San Francisco

Sari

$131 nightly

Sep 30 - Oct 1

Total with taxes and fees

A high-rise hotel with a modern design, featuring a prominent entrance and multiple balconies.

17. Modern Apartments at the Hub City views

San Francisco

$118 nightly

Sep 30 - Oct 1

Total with taxes and fees

A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

18. La Résidence Panamá

Bella Vista

Mohamad

$132 nightly

Sep 30 - Oct 1

Total with taxes and fees

A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

19. Yoo Apartamento

Bella Vista

Kevin

$136 nightly

Sep 30 - Oct 1

Total with taxes and fees

An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

20. Modern Design Apartments near Sortis

Bella Vista

Kareem

$63 nightly

Sep 30 - Oct 1

Total with taxes and fees

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Top Santa Clara Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent

"The room was so clean, the staff was so help full. The hotel is next to the Múlti Plaza so well located."

Hotel Riu Plaza Panama

8/10 Good

"We booked a suite, which was very spacious and had a great view. In addition to the full bathroom, there was also a convenient half bath near the entrance. The bed was comfortable, and having robes and slippers is always a nice touch. Breakfast was easily a 10/10! It was included with our stay and offered a great mix of traditional breakfast items and local cuisine. There were plenty of options, with different selections each day, which we really appreciated. The hotel was also conveniently located. Ubers were generally between 7–15 minutes to pretty much everywhere we needed to go, including the mall, restaurants and other places we visited. Overall, the service was good. It does help to know a little Spanish, as most of the employees spoke limited English, but we were still able to communicate and get what we needed. The biggest downside was the smell in the hallway leading to our room. There was a noticeable mildew/wet, stale smell, and a similar smell was also present in the room. We reported it and housekeeping came by, which helped a bit. We also purchased an air freshener during our stay to help with the smell. Washcloths weren’t always readily available and weren’t consistently replaced when the room was serviced, so we had to request them. The room also did not have a microwave, which would have been convenient. Aside from the smell, particularly in the hallway, which the hotel should definitely address, we thoroughly enjoyed our stay."

Megapolis Hotel Panamá

10/10 Excellent

"Execelente servicio solo como sugerencia! Se necesita un microondas en la habitación on en algún pasillo que pueda estar disponible por pasillo ya que aveces ay alimentos que se necesitan calentar 2 un mini market que pueda estar abierto las 24 horas dentro del hotel eso beneficiaría tanto al hotel como al huésped! De lo contrario todo Execelente las habitaciónes y donde se toma el desayuno es de lo mejor , muy recomendable…"

Find out more about Santa Clara

Everything you need to know about Santa Clara vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Clara vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Clara vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Clara vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Clara. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Clara in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Clara rentals

At Expedia, we put the best Santa Clara vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Clara rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Clara vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Clara. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in Santa Clara?

Yes, there are vacation rentals close to popular attractions in Santa Clara, or you can choose a secluded option if you'd like a relaxing place to stay. Santa Clara is known for its monuments.

What are some of the best vacation home rentals that Santa Clara has to offer?

Downtown Villa with Private Pool & Bar: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the larger area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are vacation rentals like in Santa Clara?

Vacation rentals are privately owned properties you can book for several days or longer in Santa Clara. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.

Santa Clara Vacation Rentals

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Check prices for these dates

Our top choices for Santa Clara vacation rentals

1. La Palma Experience

2. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

3. Dovle Residences by HMS-Preferred Member

4. Refugio Frente al Mar Vista Venao

5. La Isabela Suites

6. Corporate Stays Arcadia | Executive Furnished Apartments

7. Las Clementinas

8. Yoo Panamá by Boutique Apartments

9. Torres de Alba Hotel & Suites

10. San Francisco by Wynwood House

11. Yoo Panama Luxury Ocean View Apartment

12. Boutique Apartments Panama

13. Living 73 Panamá by Boutique Apartments

14. Modern Apartments at The Gray Prime Location

15. Cozy La Chorrera Villa With Private Patio & Nature Views

16. w* | Classy 1BR in San Francisco w/ Pool

17. Modern Apartments at the Hub City views

18. La Résidence Panamá

19. Yoo Apartamento

20. Modern Design Apartments near Sortis

Find vacation rentals that suit your style

Top Santa Clara Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Find out more about Santa Clara

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