Santa Clara Vacations from $697

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Your Santa Clara Vacation

Art, food, entertainment and more … There's so much to experience with a Santa Clara vacation package. And with the ability to customize your city getaway, it's guaranteed to be one you won't forget. Eager to sightsee but not sure where to start? Any trip to Santa Clara should include Culebra Cut. Your dream Santa Clara vacation is a couple of clicks away. Search flights, accommodations and more on Expedia for a getaway that's tailored just for you.

The Latest Santa Clara vacation packages

Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Price was $1,040, price is now $697 per person
$697
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,002 reviews)
Beautiful hotel with amazing surroundings but the restaurant is very limited and expensive and not good 😌

Reviewed on Sep 28, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,549, price is now $1,354 per person
$1,354
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,005 reviews)
Staffs were wonderful.

Reviewed on Oct 28, 2025

Kooteja Anton Valley ËRA

Kooteja Anton Valley ËRA

2 out of 5
Save 100% on your flight
Price was $1,130, price is now $713 per person
$713
per person
Jan 1 - Jan 8
found 8 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
6/10 (2 reviews)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,235, price is now $807 per person
$807
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,386 reviews)
Very clean and courteous staff. The food was good.

Reviewed on Nov 9, 2025

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,430, price is now $950 per person
$950
per person
Jan 10 - Jan 17
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,904 reviews)
the following is where The Riande Aeropuerto Hotel and Casino can improve: 1. Tell guests there is no elevator so when the guest books a balcony room, they must understand they have to use steps to lug up their suitcases to their room. We were unaware of this situation and had to pay extra to book a first floor poolside unit. 2. the "casino" is not an integral part of the hotel. We had to be escorted to and the casino (quite a long walk) with Riande security personnel. A major disappointment. 3. Unfortunately, there is a small yet significant language barrier from English to Spanish relating to communication.with hotel staff.

Reviewed on Nov 8, 2025

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Discover the most popular places to visit in Santa Clara

Culebra Cut

4/5(11 reviews)

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.

Culebra Cut

What to do in Santa Clara

Gatun Lake boat ride

Panama Canal Wildlife Boat Safari & Panamanian Brunch

$60
per adult
100% of travellers recommend
Panama Canal Wildlife Boat Safari & Panamanian Brunch
Bridge of the Americas

Private or Small Group Panama Canal & City Half-Day Tour

$67
per adult
100% of travellers recommend
Private or Small Group Panama Canal & City Half-Day Tour
7 Hours Monkey Island and Nature Walk at Soberania National Park

7 Hours Monkey Island and Nature Walk at Soberania National Park

$120
per adult
7 Hours Monkey Island and Nature Walk at Soberania National Park
See all activities in Santa Clara

Santa Clara Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Nov 17 to Nov 18
$117 total
Nov 17 - Nov 18
Total with taxes and fees
9/10 Wonderful! (4,476 reviews)
Great staff

Reviewed on Nov 8, 2025

Hotel Riu Plaza Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $118 total per night from Nov 14 to Nov 15
$118 total
Nov 14 - Nov 15
Total with taxes and fees
8.4/10 Very Good! (1,182 reviews)
Was all clean , the staff gave good service.

Reviewed on Nov 8, 2025

Megapolis Hotel Panamá
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$272 nightly
The price is $272 total per night from Dec 2 to Dec 3
$272 total
Dec 2 - Dec 3
Total with taxes and fees
7.4/10 Good! (1,006 reviews)
The breakfast was good, good selection, omelet station, great fresh fruit and juice availability. Wait staff were friendly and very service oriented. We will be back.

Reviewed on Nov 7, 2025

Dreams Playa Bonita Panama - All Inclusive
See all 1,358 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Clara Vacation Packages

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
1,400

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Frequently asked questions

How much does a Santa Clara vacation package cost?
You can snap up a vacation package to this destination from $697 on Expedia. However, how much your vacation to Santa Clara costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Clara?
You're likely to find lower rates and greater availability in September, October and December. Browse our cheap Santa Clara vacation packages and you could score some great off-season deals.
How many days is enough for Santa Clara?
The ideal duration for your Santa Clara vacation depends on what you'd like to see and do. Typically, a handful of days to a week will give you plenty of time to hit all the main attractions and explore some hidden treasures along the way.
How to find the best Santa Clara package deals?
Landing a cheap Santa Clara package deal is easy with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your maximum budget, add a few filters and browse what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most affordable Santa Clara package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Santa Clara vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and stays separately. Better still, you can customize your Santa Clara trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Santa Clara?
If you have your Santa Clara vacation dates finalized, book as early as you can to bag some incredible deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Santa Clara?

  1. Choose your travel dates: What you'd like to do in Santa Clara and your preferred season will help you decide when to get away.
  2. Figure out your budget: Ensure you have enough money to cover everything from meals and transportation to airfares and activities. Your accommodations will likely be the largest expense during your trip to Santa Clara.
  3. Use Expedia's trip planning tool to discover Santa Clara: Research every aspect of your trip to Santa Clara with this comprehensive planner. Invite friends or family to collaborate on a group trip, search for stays or things to do and make bookings.
  4. Decide how long to go for: Now that you're up to speed on Santa Clara, you can work out the ideal length of your vacation. Create a rough plan and allocate enough time to cover everything you want to do.
  5. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to pick a Santa Clara vacation package that brings all your bookings together.
  6. Book experiences or activities in advance: Whether it's a ticket to a big attraction or a day trip, you won't have to worry about missing out on Santa Clara's best offerings. Find all the fun things to do in Santa Clara with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Santa Clara vacation packages?
Your Santa Clara trip is meant to be a relaxing escape from your busy life, not a reason for money worries. So to give you a little more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.