Santa Clara

Travel Guide

A beach with waves, a boat, and a forested hill in the background.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
$141 nightly
The price is $156 total per night from Oct 25 to Oct 26
$156 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (6,078 reviews)
"Great hotel, enjoyed our stay, helpful staff, Breakfast was amazing, off the chains, large variety to choose from. Lots of healthy choices and exotic fruits. Would visit again."

Reviewed on Oct 16, 2026

Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
$95 nightly
The price is $105 total per night from Nov 8 to Nov 9
$105 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,000 reviews)
"Requesting wake-up call every day, they failed every day but one. Reported issue, got OH I AM SORRY. Breakfast buffet was good. The front desk is very slow."

Reviewed on Oct 15, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
$133 nightly
The price is $133 total per night from Oct 24 to Oct 25
$133 total
Oct 24 - Oct 25
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,795 reviews)
"being across from the mall was convenient, good locatiomn overall"

Reviewed on Oct 16, 2026

Megapolis Hotel Panamá
See all 1,776 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre

4 out of 5
Calle Colombia Y Ave.,3ra A Sur, Bella V Panama City Panama
Book a stay at this business-friendly aparthotel in Panama City. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our ...
Marriott Executive Apartments Panama City, Finisterre
Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments

4 out of 5
Calle rio mar Panama City Panamá Province
Stay at this aparthotel in Panama City. Enjoy free WiFi, a rooftop terrace, and parking (surcharge). Popular attractions Multiplaza Pacific Mall and Avenida ...
9.2/10 Wonderful! (401 reviews)
"Everything was nice"

Reviewed on Oct 14, 2026

Corporate Stays Arcadia | Executive Furnished Apartments
Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites

3.5 out of 5
Calle Eusebio A. Morales y Calle 55 Panama City Panama
Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (590 reviews)
"Breakfast need bacon to go with eggs!"

Reviewed on Oct 15, 2026

Torres de Alba Hotel & Suites
See all properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Clara attractions

Culebra Cut

8.0/10 (14 reviews)
You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.
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Things to do

Monkey and Sloth Jungle Habitat Panama Tour

Monkey and Sloth Jungle Habitat Panama Tour

$60
per adult
96% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
Magnificent Gatun lake

Monkey Watch and Gatun Lake Wildlife Safari Private Tour

$75
per adult
Monkey Watch and Gatun Lake Wildlife Safari Private Tour
Panamá Canal and Old Town

The Trilogy of Panama: Canal, Colonial History and Coastal Views

$80
per adult
The Trilogy of Panama: Canal, Colonial History and Coastal Views
Layover

Layover Tour: Panama city and Canal Visit (2 people minimum)

$75
per adult
Layover Tour: Panama city and Canal Visit (2 people minimum)
MiraLift

Transfer to Panama Canal (Miraflores Locks)

$14
per adult
100% of travellers recommend
Transfer to Panama Canal (Miraflores Locks)
Explore Panama Canal and Gatun Lake with Rainforest Hike

Explore Panama Canal and Gatun Lake with Rainforest Jungle Walk

$109
per adult
Explore Panama Canal and Gatun Lake with Rainforest Jungle Walk
See all activities in Santa Clara

Frequently asked questions

Is Santa Clara worth visiting?
Santa Clara is worth visiting for its diverse culinary scene, where travelers can enjoy a range of Asian and Latin American dining. It also offers unique experiences, such as exploring the notable Culebra Cut, making it a destination with distinct attractions.
When is the best time to visit Santa Clara?
The best time to visit Santa Clara is from October through February, when the climate is generally pleasant. For travelers seeking fewer crowds and better value, the months of April through July are a good option, offering a different experience with warmer weather.
What is Santa Clara known for?
Santa Clara is known for Culebra Cut, a significant section of the Panama Canal. This Panamanian city also offers travelers a strong Asian food culture, providing diverse and flavorful culinary experiences to explore during their visit.
What is a good itinerary length for Santa Clara?
A good itinerary length for Santa Clara is one day to see Culebra Cut. For travelers interested in local flavors, an extra day could allow for exploring the Asian, Latin American, and Italian cuisine options available in the area.
What are the top things to do in and around Santa Clara?
In Santa Clara, travelers can explore Culebra Cut, a significant landmark and point of interest.
What cuisines can you find in Santa Clara?
In Santa Clara, you can find Korean cuisine, with dishes like bulgogi, bibimbap, and kimchi. Travelers can also enjoy other Asian options such as Indian, Chinese, and Japanese, alongside Latin American choices like Mexican tacos, and Italian dishes.
Can I book a refundable hotel in Santa Clara?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santa Clara by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santa Clara with Expedia?
Expedia makes it easier to plan your Santa Clara trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santa Clara?
The best choice depends on your travel style. Hotels in Santa Clara can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santa Clara trip on Expedia?
Once you've booked your Santa Clara trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santa Clara trip?
Expedia offers customer support before, during, and after your Santa Clara trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santa Clara?
If it's your first trip to Santa Clara, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santa Clara hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santa Clara hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

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