Apartments in Santa Cruz for Rent

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Find vacation rentals that suit your style

Apartment image
Apartments
Apartments
apart-hotel image
Aparthotels
Aparthotels

Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10

Our top choices for Santa Cruz apartments

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

1. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
$22 nightly
The price is $22
Nov 12 - Nov 13
Apart Hotel Premium Suites Santa Cruz
A modern rooftop pool with a city view, wooden flooring, and a seating area.

2. AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (3 reviews)
"Clean room, great staff "
Canada
Peter
$27 nightly
The price is $27
Nov 12 - Nov 13
AMERICA APARTMENTS
A modern building with a glass facade, a pool area with sun loungers, and a clear blue sky.

3. POX: 24th Floor, Green Tower | Luxury and Panoramic Views

POX: 24th Floor, Green Tower | Luxury and Panoramic Views
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
$97 nightly
The price is $97
Nov 12 - Nov 13
POX: 24th Floor, Green Tower | Luxury and Panoramic Views
A rooftop pool with lounge chairs and a cityscape view at sunset.

4. 58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed

58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed
Equipetrol
8.8 out of 10, Excellent, (3 reviews)
$49 nightly
The price is $49
Nov 30 - Dec 1
58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed
A modern kitchen with a black countertop, stainless steel appliances, and a built-in oven.

5. Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!

Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!
Santa Cruz de la Sierra
$49 nightly
The price is $49
Nov 18 - Nov 19
Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!
A rooftop swimming pool with a clear view of the city skyline and a partly cloudy sky.

6. Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"We arrived at 12:30 am due to our flight and I let the host know of our late arrival time. He had no problem. When checking in I made an error and I couldn’t figure out how to get there. I called the host as late as it was, he answered no problem and was super nice and helpful. He was very communicative although out our stay. Room was fully functional. Had a kitchen with all the necessary utensils, living room area with a tv and a couch that became a bed for our kids. Private master bedroom...
Canada
Evelyn
$26 nightly
The price is $26
Nov 30 - Dec 1
Menacho Apartment - Mangales Blue - Norte
A rooftop pool with clear blue water, surrounded by palm trees and plants, overlooking a cityscape with modern buildings.

7. Apartment with a Balcony & View / Pool / Gym at Equipe

Apartment with a Balcony & View / Pool / Gym at Equipe
Equipetrol
$54 nightly
The price is $54
Nov 23 - Nov 24
Apartment with a Balcony & View / Pool / Gym at Equipe
A rooftop pool with lounge chairs and a cityscape view at sunset.

8. Apartment with a balcony, pool, fitness center, and coworking space at Equipe

Apartment with a balcony, pool, fitness center, and coworking space at Equipe
Equipetrol
$47 nightly
The price is $47
Nov 23 - Nov 24
Apartment with a balcony, pool, fitness center, and coworking space at Equipe
A modern kitchen with dark cabinetry, a dining area with a black table and chairs, and a living room with a sofa and a large abstract painting.

9. Aqua: Loft Artistico Urbano

Aqua: Loft Artistico Urbano
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Excellent atencion todo muy comodo bonito limpio gracias"
United States
Nestor C.
$60 nightly
The price is $60
Nov 30 - Dec 1
Aqua: Loft Artistico Urbano
A rooftop pool with clear blue water, surrounded by lounge chairs and potted plants.

10. Inspiring Views • Enveloping Comfort

Inspiring Views • Enveloping Comfort
Equipetrol
$47 nightly
The price is $47
Nov 18 - Nov 19
Inspiring Views • Enveloping Comfort
A modern office space with glass walls, a long table with chairs, and several round ottomans.

11. Enchanting studio with AC in Santa Cruz de la Sierra

Enchanting studio with AC in Santa Cruz de la Sierra
Equipetrol
$39 nightly
The price is $39
Nov 12 - Nov 13
Enchanting studio with AC in Santa Cruz de la Sierra
A rooftop terrace with a pool, outdoor seating, and a view of surrounding buildings.

12. A Must-See: Studio Apartment in Sirari-Equipetrol

A Must-See: Studio Apartment in Sirari-Equipetrol
Santa Cruz de la Sierra
$50 nightly
The price is $50
Nov 25 - Nov 26
A Must-See: Studio Apartment in Sirari-Equipetrol
A rooftop pool with clear blue water, surrounded by palm trees and a cityscape in the background.

13. Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Equipetrol
$40 nightly
The price is $40
Nov 14 - Nov 15
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
A modern high-rise building with multiple floors, large windows, and a flat roof.

14. Fully furnished apartment in a prime location in Santa Cruz, 5 minutes from Manzana 40.

Fully furnished apartment in a prime location in Santa Cruz, 5 minutes from Manzana 40.
Santa Cruz de la Sierra
$63 nightly
The price is $63
Nov 15 - Nov 16
Fully furnished apartment in a prime location in Santa Cruz, 5 minutes from Manzana 40.
A modern living room with a dining area, a sofa, a red chair, a coffee table, and a bookshelf.

15. Beautiful Loft in a brand new Condo, 10 minutes from business center.

Beautiful Loft in a brand new Condo, 10 minutes from business center.
Santa Cruz de la Sierra
2.0 out of 10, (1 review)
$49 nightly
The price is $49
Nov 12 - Nov 13
Beautiful Loft in a brand new Condo, 10 minutes from business center.
A modern hotel with a prominent entrance, a glass facade, and a palm tree in the foreground.

16. Curupau | Modern 1-Bedroom Apartment with Pool & Parking Space

Curupau | Modern 1-Bedroom Apartment with Pool & Parking Space
Santa Cruz de la Sierra
$39 nightly
The price is $39
Nov 12 - Nov 13
Curupau | Modern 1-Bedroom Apartment with Pool & Parking Space
A modern kitchen with a built-in oven, a sink, and a window.

17. Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.

Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.
Santa Cruz de la Sierra
$38 nightly
The price is $38
Nov 16 - Nov 17
Hermoso apartamento con dos habitaciones en la zona más segura de Santa Cruz.
A modern living room with a sofa, a dining table with chairs, and a bed with a white canopy.

18. Elegante departamento Sirari Equipetrol

Elegante departamento Sirari Equipetrol
Santa Cruz de la Sierra
$59 nightly
The price is $59
Nov 12 - Nov 13
Elegante departamento Sirari Equipetrol
A rooftop pool with lounge chairs and a cityscape view at sunset.

19. Apartment with a workspace / pool / gym / sleeper sofa

Apartment with a workspace / pool / gym / sleeper sofa
Equipetrol
$47 nightly
The price is $47
Nov 30 - Dec 1
Apartment with a workspace / pool / gym / sleeper sofa
A modern outdoor pool area with a rectangular pool, lounge seating, and a covered patio.

20. Experience comfort, luxury, and tranquility

Experience comfort, luxury, and tranquility
Equipetrol
$90 nightly
The price is $90
Nov 20 - Nov 21
Experience comfort, luxury, and tranquility
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Frequently Asked Questions

What's it like to stay at an apartment in Santa Cruz?

You'll find 198 apartments to choose from in Santa Cruz for your stay. During your trip to the area, you can visit the shops.

Why would you choose apartments instead of traditional hotels?

An apartment is often more spacious than a traditional hotel room and includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home but also for solo travelers who want to stay in at night and plan out their next day.

What's the best apartment for a stay in Santa Cruz?

Here is a popular apartment to consider: Apart Hotel Premium Suites Santa Cruz: Includes free WiFi, furnished balconies, and separate dining areas. Free parking and onsite laundry facilities are on site.

How many apartments should I expect to find in Santa Cruz?

Expedia has 198 apartments to book in Santa Cruz.

What will the weather be like when I travel to Santa Cruz?

Though weather is just one factor, it can really affect your travel plans, especially when you're planning an extended stay in Santa Cruz. The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

What should I see and do in Santa Cruz?

Santa Cruz is known for its shops. Santa Cruz Zoo and Play Land Amusement Park are a couple of family-friendly sights, whereas cultural attractions include Ethno-folkloric Museum and Cine Center. While here, Plaza 24 de Septiembre and Blacutt Square are other places worth a visit.

What's the best way to get to and around Santa Cruz?

Knowing a bit about the transportation options can make your trip smoother when you get to your destination. Fly into Santa Cruz (SRZ-El Trompillo), which is located 1.2 mi (1.9 km) from the city center. Otherwise, look for flights into Santa Cruz (VVI-Viru Viru Intl.), which is 9.8 mi (15.8 km) away. If you want to explore the larger area, hop aboard a train at Santa Cruz de la Sierra Station.

Explore a world of travel with Expedia