A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Check availability on Santa Cruz 4 Star Hotels

Tonight
Aug 15 - Aug 16
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Aug 16 - Aug 17
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Aug 21 - Aug 23
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Aug 28 - Aug 30

Our top choices for Santa Cruz 4-star hotels

1. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
Santa Cruz
United States
Pluetina
$98 nightly
$98 total
Aug 16 - Aug 17
TRYP by Wyndham Santa Cruz

2. Camino Real Hotel

Camino Real Hotel
Santa Cruz
United States
Austin
$115 nightly
$115 total
Sep 14 - Sep 15
Camino Real Hotel

3. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
United States
imilse de
$74 nightly
$74 total
Aug 27 - Aug 28
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
United States
GONZALO
$148 nightly
$148 total
Aug 30 - Aug 31
Swissôtel Santa Cruz De La Sierra

5. Hotel Maywa

Hotel Maywa
Santa Cruz
United States
Alex
Hotel Maywa

6. Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa
Santa Cruz
Sweden
Charlotte
Buganvillas Hotel Suites & Spa

7. Royal Lodge Hotel

Royal Lodge Hotel
Santa Cruz
Argentina
Anonymous traveler
Royal Lodge Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

AV ROCA CORONADO 901 Santa Cruz
$105 nightly
$105 total
Sep 1 - Sep 2
Novotel Santa Cruz De La Sierra
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
$106 nightly
$106 total
Aug 21 - Aug 22
9/10 Wonderful! (243 reviews)
Marriott Santa Cruz de la Sierra Hotel
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A colonial-style building with a bell tower, palm trees, and a paved walkway.

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

The preparation of any trip kicks off with choosing a spot. Santa Cruz has been a popular destination with guests because of everything it offers. Location is everything, but that applies to more than the area you are flying into. Now that you have got a feel for this city, it's time you to learn a little more about your home away from home.

Hotels as Gorgeous as the City

Santa Cruz saw its fair share of visitors last year. Expedia's comment section contains comments which can help you select which hotel is the right fit for your trip. The hotels found here aim to make your stay as delightful as your days spent exploring Santa Cruz. These hotels work to make their facilities and grounds inviting from the minute you step out of your car. You won't need to venture far to find a delectable breakfast, to keep up with your exercise schedule, or for an invigorating plunge during your stay with everything they provide. Santa Cruz has terrific accommodations that offer the absolute perfect holiday.

Rooms have been fashioned to keep your utmost comfort in mind, with amenities like premium bedding, specially designed bathroom products, and in-room coffee or tea. So, lay back and relax. Moreover, if you find that you are need of anything else, you can trust the staff will work their hardest to ensure you stay happy during your time. These hotels are so nice that you'll regret the day you have to leave.

Book a 4-Star Hotel in Santa Cruz Today!

Your getaway to Santa Cruz should be one where you don't have to trouble yourself about the little things. Make sure to book soon. With so few hotels, and plenty of people desiring to take a trip to here, you may miss out on your perfect room.

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
Kick back and relax in 4-star hotel comfort at TRYP by Wyndham Santa Cruz. Highly recommended by many of our guests, it comes with a swimming pool and concierge services. Also consider Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Concierge services and complimentary breakfast help make this getaway another sought-after choice in Santa Cruz.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
With Expedia's handy filter tool, locking in a fabulous deal on a 4-star hotel in Santa Cruz just got easier. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and choose a hotel that best suits your style and budget.
  • Search for the lowest price from $105
What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you decide to spend your vacation at a 4-star hotel in Santa Cruz, you'll usually find lots of conveniences to ensure you're relaxed, such as a pool, restaurant and gym. You can experience top-quality service and upmarket surroundings. Choose a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and indulgent turndown services. You'll most likely get more amenities and premium services at a 5-star stay, though both are fabulous options for luxury guests.

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