Find hotels in Southeast Minnesota, MN from $48

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Compare 739 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN, 55901
Fully refundableReserve now, pay when you stay
The price is $115 per night from Feb 8 to Feb 9
$115
per night
Feb 8 - Feb 9
4.28 mi from city center
3.7/5 Good! (1,074 reviews)
"The access to Mayo services"

Reviewed on Feb 1, 2023

Kahler Inn and Suites - Mayo Clinic Area
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN, 55902
Fully refundableReserve now, pay when you stay
The price is $139 per night from Feb 9 to Feb 10
$139
per night
Feb 9 - Feb 10
4.36 mi from city center
3.7/5 Good! (1,058 reviews)
Perfect location for a visit to Mayo Clinic
"I was in Rochester for a medical procedure at Mayo Clinic. This was the perfect location as it was closest to all of the buildings I visited for my appointments. The underground subway system connected us to Mayo without the need to go outside in the cold Minnesota winter temperatures. The room was ..."

Reviewed on Feb 1, 2023

Kahler Grand Hotel
GuestHouse Inn & Suites Rochester
2.5 out of 5
435 16th Ave Nw, Rochester, MN, 55901
Fully refundableReserve now, pay when you stay
The price is $68 per night from Feb 8 to Feb 9
$68
per night
Feb 8 - Feb 9
3.65 mi from city center
3.9/5 Very Good! (1,046 reviews)
"only thing bad was the pool area was closed"

Reviewed on Jan 30, 2023

GuestHouse Inn & Suites Rochester

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Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
110 Civic Center Drive NW, Rochester, MN, 55901
Fully refundable
The price is $139 per night from Feb 10 to Feb 11
$139
per night
Feb 10 - Feb 11
4.48 mi from city center
4.5/5 Wonderful! (293 reviews)
"Clean, smart room. A bit distant from Mayo Clinic. Breakfast is basic."

Reviewed on Feb 5, 2023

Hyatt House Rochester/Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
3.5 out of 5
101 11TH AVENUE SW, SUITE A, Rochester, MN, 55902
Fully refundable
The price is $103 per night from Feb 18 to Feb 19
$103
per night
Feb 18 - Feb 19
3.73 mi from city center
4.7/5 Exceptional! (298 reviews)
Excellent
"It is really a very beautiful place inside. The amenities in the room are top notch. They provide great smelling soap, shampoo, condition as well as fitness equipment right in the room."

Reviewed on Jan 30, 2023

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Holiday Inn Hotel & Suites Minneapolis - Lakeville, an IHG Hotel
3 out of 5
20800 Kenrick Ave, Lakeville, MN, 55044
Fully refundable
The price is $137 per night from Feb 14 to Feb 15
$137
per night
Feb 14 - Feb 15
58.05 mi from city center
4.4/5 Excellent! (342 reviews)
"Very nice front desk people"

Reviewed on Feb 1, 2023

Holiday Inn Hotel & Suites Minneapolis - Lakeville, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN, 55904
Fully refundable
The price is $108 per night from Feb 19 to Feb 20
$108
per night
Feb 19 - Feb 20
4.44 mi from city center
4.3/5 Excellent! (286 reviews)
Planning to stay again
"Easy access to Mayo via the skyway. 10 minute walk. Room was clean and comfortable. The market was a great option for late night snacks. Crave was delicious!! Will stay again when back for a three month checkup."

Reviewed on Jan 29, 2023

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
3 out of 5
101 11th Ave SW, Rochester, MN, 55902
Fully refundable
The price is $114 per night from Feb 18 to Feb 19
$114
per night
Feb 18 - Feb 19
3.73 mi from city center
4.6/5 Exceptional! (152 reviews)
Love this place!
"Amazing service, we were there for a volleyball tournament. Breakfast didn’t start till 7:30 and we needed to be out of their way before that. The staff in charge made up bags of muffins and fruit for us in the morning and also gave us a coupon for the hotel breakfast at the restaurant that opened ..."

Reviewed on Feb 5, 2023

Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN, 55904
Fully refundableReserve now, pay when you stay
The price is $76 per night from Mar 5 to Mar 6
$76
per night
Mar 5 - Mar 6
5.03 mi from city center
4.2/5 Very Good! (1,029 reviews)
Great stay
"We were very pleased with all aspects of our stay. We took an early morning shuttle before breakfast was offered.all employees were very friendly. I would definitely stay here again"

Reviewed on Jan 23, 2023

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hilton Rochester Mayo Clinic Area
3.5 out of 5
10 East Center Street, Rochester, MN, 55904
Fully refundableReserve now, pay when you stay
The price is $169 per night from Feb 18 to Feb 19
$169
per night
Feb 18 - Feb 19
4.49 mi from city center
4.9/5 Exceptional! (214 reviews)
Mayo Clinic stay
"It was absolutely amazing. 100/10 stars from me."

Reviewed on Feb 4, 2023

Hilton Rochester Mayo Clinic Area
Days Inn & Suites by Wyndham Rochester Mayo Clinic South
2.5 out of 5
3595 Commercial Drive SW, Rochester, MN, 55904
Fully refundableReserve now, pay when you stay
The price is $48 per night from Mar 10 to Mar 11
$48
per night
Mar 10 - Mar 11
4.59 mi from city center
3.6/5 Good! (938 reviews)
"Nice property VERY Comfy beds Could have been a bit cleaner in the common areas"

Reviewed on Jan 26, 2023

Days Inn & Suites by Wyndham Rochester Mayo Clinic South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 out of 5
1517 16th St Sw, Rochester, MN, 55902
The price is $88 per night from Feb 19 to Feb 20
$88
per night
Feb 19 - Feb 20
2.96 mi from city center
4.1/5 Very Good! (238 reviews)
Great pre-Mayo stay
"Very nice accommodation. Spacious rooms with comfortable beds."

Reviewed on Jan 12, 2023

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
St James Hotel, a Historic Hotel of America
3.5 out of 5
406 Main St., Red Wing, MN, 55066
Fully refundableReserve now, pay when you stay
The price is $138 per night from Feb 8 to Feb 9
$138
per night
Feb 8 - Feb 9
39.13 mi from city center
4.5/5 Wonderful! (838 reviews)
"Friendly, pleasant check-in."

Reviewed on Feb 5, 2023

St James Hotel, a Historic Hotel of America
Brentwood Inn & Suites
2.5 out of 5
123 Fourth Ave. NW, Rochester, MN, 55901
Fully refundableReserve now, pay when you stay
The price is $120 per night from Feb 9 to Feb 10
$120
per night
Feb 9 - Feb 10
4.29 mi from city center
4.2/5 Very Good! (969 reviews)
"Was good value"

Reviewed on Feb 6, 2023

Brentwood Inn & Suites
Med City Hotel & Suites
2.5 out of 5
4141 Maine Avenue SE, Rochester, MN, 55904
Fully refundable
The price is $68 per night from Feb 17 to Feb 18
$68
per night
Feb 17 - Feb 18
4.94 mi from city center
4.3/5 Excellent! (1,009 reviews)
"Considering the property is under renovation, we were very pleased. Can’t wait to come back when it’s finished."

Reviewed on Jan 28, 2023

Med City Hotel & Suites
Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel
3 out of 5
2350 Commerce Drive NW, Rochester, MN, 55901
Fully refundable
The price is $110 per night from Feb 19 to Feb 20
$110
per night
Feb 19 - Feb 20
3.66 mi from city center
4.3/5 Excellent! (303 reviews)
Nice stay
"Nice hotel with friendly staff. Had a quiet and comfortable room. Pool/Hot tub pretty good. Breakfast had several options available, but the cheese omelet was below average. Not much else to complain about. Would stay here again in the future."

Reviewed on Jan 31, 2023

Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3 out of 5
161 13th Ave Sw, Rochester, MN, 55902
Fully refundableReserve now, pay when you stay
The price is $98 per night from Feb 10 to Feb 11
$98
per night
Feb 10 - Feb 11
3.5 mi from city center
4.5/5 Wonderful! (526 reviews)
"Great place!"

Reviewed on Feb 4, 2023

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Aspen Suites
3 out of 5
1211 2nd Street, Rochester, MN, 55902
Fully refundableReserve now, pay when you stay
The price is $150 per night from Feb 10 to Feb 11
$150
per night
Feb 10 - Feb 11
3.58 mi from city center
4.4/5 Wonderful! (416 reviews)
Easy access to St. Mary’s Hospital
"Nice hotel and perfect service. Right across street from the hospital-perfect location for my husbands surgery."

Reviewed on Jan 24, 2023

Aspen Suites
Hampton Inn & Suites Rochester-North
2.5 out of 5
2870 59th Street NW, Rochester, MN, 55901
Fully refundableReserve now, pay when you stay
The price is $93 per night from Feb 16 to Feb 17
$93
per night
Feb 16 - Feb 17
6.22 mi from city center
4.6/5 Wonderful! (776 reviews)
"Nice clean hotel, felt bad for nice front desk lady who was overwhelmed because she was there by herself but that wasn’t her fault. Phone was ringing non stop. She was very pleasant to us at check-in."

Reviewed on Feb 6, 2023

Hampton Inn & Suites Rochester-North
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 out of 5
155 16th Avenue SW, Rochester, MN, 55902
Fully refundable
The price is $104 per night from Feb 12 to Feb 13
$104
per night
Feb 12 - Feb 13
3.4 mi from city center
4.3/5 Excellent! (486 reviews)
"great location, friendly staff - pool closed, 3rd fl ice machine oos several months so when 1st fl broke no ice, breakfast menu fairly good but taste so so"

Reviewed on Feb 7, 2023

Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southeast Minnesota

Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota
  • Rochester showing skyline and a city

    Downtown Rochester

    2 out of top 10 points of interest in this area
    4.5/5Wonderful!(250 area reviews)

    If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

    Find hotels in Downtown Rochester

Stay near popular Southeast Minnesota attractions

  • Image for Minnesota Zoo

    Minnesota Zoo

    4.5/5(280 reviews)

    Go wild in this animal park with more than 500 species, plus a petting farm, IMAX theater and bird show.

    See properties
    Minnesota Zoo

Southeast Minnesota hotels information

Number of reviews
12291
Accommodation
739 hotels
Lowest Price
$48
Highest Price
$169

Recent reviews of Southeast Minnesota hotels
Expedia verified reviews

  • Brentwood Inn & Suites

    Brentwood Inn & Suites

    5/5 Excellent
    "Was good value "
    A verified traveler stayed at Brentwood Inn & Suites
    Posted 20 hours ago
    Brentwood Inn & Suites

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