
Southwest Coast Florida Vacations from $308
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Your Southwest Coast Florida Vacation
Make planning your next great adventure a breeze with a Southwest Coast Florida vacation package. If it's coastal beaches, nature and dining you're looking for, you won't be disappointed. With so much to see on a trip to Southwest Coast Florida, it can be hard to know where to begin. Kick off your journey in Tampa at Busch Gardens Tampa Bay and Raymond James Stadium — two much-loved attractions here. Another great city to add to your itinerary is Sarasota. Don't miss Bay Island and Siesta Key Beach. Expedia has hotels, flights and all your other travel needs to help you organize your own tailored Southwest Coast Florida vacation today.
The Latest Southwest Coast Florida vacation packages

Cavalier Hotel South Beach
Reviewed on Jul 31, 2025




President Villa
Reviewed on Jul 7, 2025
Where to stay in Southwest Coast Florida

North Captiva
Visitors to North Captiva enjoy its beaches, and if you want to do some exploring, North Captiva Island Beach is worth a stop.
Discover the most popular places to visit in Southwest Coast Florida

Siesta Key Beach
The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

Lido Beach
Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Venice Beach
Beachside bliss awaits at a Florida coastal gem where you can swim, fish and hunt for ancient fossils in the sand and beneath the waves.
Southwest Coast Florida Hotel Deals

Kompose Boutique Hotel
Reviewed on Jul 28, 2025

Naples Grande Beach Resort
Reviewed on Jul 30, 2025

Sunseeker Resort Charlotte Harbor
Reviewed on Jul 31, 2025
More vacations you might like
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Fort Myers Hotels
- Hotels near Walker Honey Farm
- Hotels near Revolution Cable Park
- Hotels near Alabama Grove Terrace
- Hotels near Rainbow Groves
- Suncoast Estates Hotels
- Hotels near Morse Shores Shopping Center
- Hotels near Terry Park Ball Field
- Hotels near Manatee World
- North Fort Myers Hotels
- Motels in North Fort Myers
- Cheap Hotels in North Fort Myers
- 4 Star Hotels in North Fort Myers
- Best Western Hotels in North Fort Myers
- Red Roof Inn Hotels in North Fort Myers
- Pet-friendly Hotels in North Fort Myers
- Condo Rentals in North Fort Myers
- Hotels on the River in North Fort Myers
- Beach Hotels in North Fort Myers
- Cabin Rentals in North Fort Myers
- Vacation Homes in North Fort Myers
- Extended Stay Hotels in North Fort Myers
- Cottages in North Fort Myers
- La Quinta Inn & Suites Hotels in North Fort Myers
- Villas in North Fort Myers
- RV Parks in North Fort Myers
- Oceanfront Hotels in North Fort Myers
- Hotels with Bars in North Fort Myers
- Gay friendly Hotels in North Fort Myers
- 5 Star Hotels in North Fort Myers
- Hotels with Connecting Rooms in North Fort Myers
- Hotels with Restaurants in North Fort Myers
- Farmstay in North Fort Myers
- B&B in North Fort Myers
- Waterpark Hotels in North Fort Myers
- Resorts in North Fort Myers
- Luxury Hotels in North Fort Myers
- Hotels with Laundry Facilities in North Fort Myers
- Guest Houses in North Fort Myers
- Houseboats in North Fort Myers
- Historic Hotels in North Fort Myers
- Hotels with Free Breakfast in North Fort Myers
- 3 Star Hotels in North Fort Myers
- Hotels & Resorts for Couples in North Fort Myers
- Fishing Resorts & in North Fort Myers
- Hotels with Balconies in North Fort Myers
- Hyatt Hotels in North Fort Myers
- Condo Resorts in North Fort Myers
- Hotels near East 1st Street
- Cheap Hotels in Fort Myers
- Hotels near Shell Factory and Nature Park
- Hotels near Diplomat
- Hotels near Sabal Springs
- Hotels near Manatee Park
- Hotels near Sidney & Berne Davis Art Center
- Hotels near Fort Myers River District
- Hotels near Florida Repertory Theater
- Hotels near Butterfly Estates
- Walker Honey Farm
- Revolution Cable Park
- Morse Shores Shopping Center
- Terry Park Ball Field
- Manatee World
- North Fort Myers Vacations
- Fort Myers Vacations
- Visit North Fort Myers
- Manatee Park
- Shell Factory and Nature Park
- Art of the Olympians Museum
- Florida Repertory Theater
- Centennial Park
- Harborside Event Center
- Car rentals near Fort Myers
- Car rentals near Revolution Cable Park
- Car rentals near Suncoast Estates
- AirCar Car rental Rental Cars in Suncoast Estates
- Car rentals near Tice
- Car rentals near North Fort Myers
- Enterprise Rental Cars in North Fort Myers
- Budget Rental Cars in North Fort Myers
- Hertz Rental Cars in North Fort Myers
- Nextcar Rental Cars in North Fort Myers
- Payless Rental Cars in North Fort Myers
- Greenmotion Rental Cars in North Fort Myers
- Dollar Rent A Car Rental Cars in North Fort Myers
- Thrifty Car Rental Rental Cars in North Fort Myers
- Sixt Rental Cars in North Fort Myers
- Mex Rent A Car Rental Cars in North Fort Myers
- Firefly Rental Cars in North Fort Myers
- Avis Rental Cars in North Fort Myers
- Easirent Rental Cars in North Fort Myers
- Van Car Rentals in North Fort Myers
- Car rentals near Shell Factory and Nature Park