Title: The Best 4 Star Hotels in Southeastern Indiana from $106 | Expedia.com

[Southeastern Indiana Travel Guide](https://expedia.com/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.com/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.com/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.com/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Car Rentals in Southeastern Indiana](https://expedia.com/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.com/Southeastern-Indiana.d6233889.Destination-Travel-Guides)

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## Check availability on Southeastern Indiana 4 Star Hotels

Tonight

[Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=6233889&startDate=2026-02-05&endDate=2026-02-06&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=6233889&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6233889&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6233889&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southeastern Indiana 4-star hotels

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/0261f02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.com/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(4,042 reviews)

"Great hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lazaro

$152 nightly

$179 total

Feb 18 - Feb 19

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/0bb1b93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

[](https://www.expedia.com/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,777 reviews)

"Amazing stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin

$207 nightly

$244 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/edc62f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.com/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,150 reviews)

"Great room and breakfast. Close to several nice restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Crystal

$115 nightly

$135 total

Feb 15 - Feb 16

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/764d3439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.com/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,180 reviews)

"Very beautiful facility and great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

$171 nightly

$201 total

Feb 18 - Feb 19

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/9764f52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

[](https://www.expedia.com/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,034 reviews)

"Spotless room and courteous staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$125 nightly

$147 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.com/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,001 reviews)

"Location and the staff was fabulous."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Madeline

$183 nightly

$216 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/ecfda21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/06086a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/1a50697e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Louisville

[](https://www.expedia.com/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

Downtown Louisville

8.8/10

Excellent

(1,001 reviews)

"Delicious Old Fashion. Great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JOHN

$156 nightly

$184 total

Feb 15 - Feb 16

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Single Room, 1 King Bed, City View | Frette Italian sheets, premium bedding, free WiFi, bed sheets](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f924fe21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

[](https://www.expedia.com/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,004 reviews)

"Property was very well taken care of and unique. Staff was friendly and helpful. Room was very nice and the price was great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erica

$206 nightly

$242 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/1c073add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Living area | 55-inch flat-screen TV with digital channels, Smart TV, pay movies](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

[](https://www.expedia.com/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,001 reviews)

"Very nice hotel. Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad

$197 nightly

$232 total

Feb 28 - Mar 1

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/cf849375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

[](https://www.expedia.com/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(444 reviews)

"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

$210 nightly

$247 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/cb95631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Corner](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Bourré Bonne Louisville, Curio Collection by Hilton

[](https://www.expedia.com/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(70 reviews)

"i love this place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

THANH

$171 nightly

$202 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area | 55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/12e6fe89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.com/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1,002 reviews)

"The area was congested but the motel was good. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Byrd

$148 nightly

$174 total

Feb 26 - Feb 27

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/89d26e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down comforters, memory foam beds](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Suite, 1 King Bed, Non Smoking | Premium bedding, down comforters, memory foam beds](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/d0d55041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

[](https://www.expedia.com/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(119 reviews)

"The check-in process was simple and easy, the room was spotless and had so many amenities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grace

$154 nightly

$179 total

Feb 19 - Feb 20

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/033ac7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/19f1cd24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Pepin Mansion Historic B&B

[](https://www.expedia.com/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

New Albany

9.8/10

Exceptional

(657 reviews)

"The room was spotless and Ryan was very efficient with getting back with me when I had questions regarding parking or anything and he was very helpful because I was a late check in"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

LaTonya

$94 nightly

$106 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/af73a8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Non Smoking | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/48d338aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking | In-room dining](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/57a6d9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CozySuites at Nulu

[](https://www.expedia.com/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

Downtown Louisville

8.2/10

Very Good

(26 reviews)

"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

$169 nightly

$196 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room dining](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e906c2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/6ec16319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Louisville North-Clarksville

[](https://www.expedia.com/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

Clarksville

9.8/10

Exceptional

(46 reviews)

"room very good i love hotel ❤️"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kartar

[](https://www.expedia.com/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.com/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1 review)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

$215 nightly

$242 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | View from room](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/fa524ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | Living area | Flat-screen TV, Netflix, video library](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/b618c806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/aebabcae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

[](https://www.expedia.com/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

Sellersburg

9.4/10

Exceptional

(10 reviews)

"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

[](https://www.expedia.com/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/d5f75e71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | Living area | 42-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/340ade50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | Living area | 42-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/63eb2392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/0d1a5ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Stunning Nulu CozySuites

[](https://www.expedia.com/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information)

Downtown Louisville

[](https://www.expedia.com/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a05fd67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a50f3b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/f2f02b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/3bec0b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hawthorn Suites by Wyndham Louisville North

[](https://www.expedia.com/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information)

Jeffersonville

7.4/10

Good

(944 reviews)

"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

alexis

[](https://www.expedia.com/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information)

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## Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

[See all hotels in Southeastern Indiana](https://www.expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&adults=2&regionId=6233889)

![Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Southeastern Indiana Hotel Reviews

## Find out more about Southeastern Indiana

## Southeastern Indiana Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southeastern Indiana, United States of America are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southeastern Indiana 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southeastern Indiana. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southeastern Indiana, United States of America, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southeastern Indiana hotels offer everything your heart desires.

## Frequently asked questions

### What are the best 4-star hotels in Southeastern Indiana?

### How much does it cost to stay in a 4-star hotel in Southeastern Indiana?

> - Search for the lowest price from $106

### What's the difference between 5-star and 4-star hotels in Southeastern Indiana?