Find 4 Star Hotels in Southeastern Indiana from $106

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Check availability on Southeastern Indiana 4 Star Hotels

Our top choices for Southeastern Indiana 4-star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,068 reviews)
"Rooms were clean and staff were friendly! "
United States
Amy
$160 nightly
The price is $188
Feb 16 - Feb 17
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,769 reviews)
"Amazing stay! "
United States
Erin
$207 nightly
The price is $244
Feb 16 - Feb 17
Total with taxes and fees
Omni Louisville Hotel

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,157 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
$115 nightly
The price is $135
Mar 8 - Mar 9
Total with taxes and fees
Embassy Suites Louisville Downtown

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,184 reviews)
"Beautiful old hotel with a fantastic bar in the lobby"
United States
Karen
$178 nightly
The price is $210
Feb 15 - Feb 16
Total with taxes and fees
The Brown Hotel

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,037 reviews)
"Spotless room and courteous staff "
United States
Mary
$135 nightly
The price is $159
Feb 26 - Feb 27
Total with taxes and fees
Hotel Genevieve part of JdV by Hyatt

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,004 reviews)
"Great room, super kind staff"
United States
Rachel
$183 nightly
The price is $216
Feb 17 - Feb 18
Total with taxes and fees
21c Museum Hotel Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,001 reviews)
"Everything was just excellent on the day I stayed."
United States
Peggy
$148 nightly
The price is $174
Feb 28 - Mar 1
Total with taxes and fees
Hyatt Regency Louisville

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,001 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
$188 nightly
The price is $221
Feb 15 - Feb 16
Total with taxes and fees
The Grady

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice hotel. Great stay!"
United States
Brad
$206 nightly
The price is $242
Mar 15 - Mar 16
Total with taxes and fees
Louisville Marriott Downtown

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (444 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
$195 nightly
The price is $229
Mar 8 - Mar 9
Total with taxes and fees
Hotel Distil, Autograph Collection

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (72 reviews)
"i love this place"
United States
THANH
$171 nightly
The price is $202
Feb 22 - Feb 23
Total with taxes and fees
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,001 reviews)
"The area was congested but the motel was good. "
United States
Byrd
$148 nightly
The price is $174
Feb 26 - Feb 27
Total with taxes and fees
Seelbach Hilton Louisville Downtown

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (120 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
$159 nightly
The price is $185
Mar 15 - Mar 16
Total with taxes and fees
Stellar Suites

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (664 reviews)
"The room was fantastic. Great location. Breakfast was excellent!! Mimi, the innkeeper, was gracious and very helpful with restaurant recommendations. Truly enjoyed my stay. "
United States
Kimberly
$94 nightly
The price is $106
Feb 15 - Feb 16
Total with taxes and fees
The Pepin Mansion Historic B&B

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.0 out of 10, Very Good, (27 reviews)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
$169 nightly
The price is $196
Mar 9 - Mar 10
Total with taxes and fees
CozySuites at Nulu

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (46 reviews)
"room very good i love hotel ❤️"
United States
Kartar
stayAPT Suites Louisville North-Clarksville

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1 review)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
$215 nightly
The price is $242
Feb 17 - Feb 18
Total with taxes and fees
The Reserve on Main

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
TWO Stunning Nulu CozySuites

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944 reviews)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and top sights like KFC Yum Center—discover it all in Southeastern Indiana.

Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people

Top Southeastern Indiana Hotel Reviews

Find out more about Southeastern Indiana

Southeastern Indiana Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southeastern Indiana, United States of America are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southeastern Indiana 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southeastern Indiana. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southeastern Indiana, United States of America, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southeastern Indiana hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You can find a range of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a customer favorite in this city that offers a swimming pool and massage services. Another getaway that gets excellent reviews from travelers is Hyatt Regency Louisville. Designer toiletries and a swimming pool help make it their number one choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
To find a 4-star hotel in Southeastern Indiana that fits your budget, make use of Expedia's handy search filters. Browse the available options during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most wallet-friendly escape first.

  • Search for the lowest price from $106

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
Treat yourself to luxury living during your Southeastern Indiana vacation by staying at a 4-star hotel. As well as featuring upscale accommodations, these properties are typically packed with amenities like complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and unforgettable one. Round-the-clock concierge assistance, luxurious spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.