Title: Southeast Missouri Car Rental - Free Cancellation Options - Expedia.com [Southeast Missouri Travel Guide](https://expedia.com/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Flights to Southeast Missouri](https://expedia.com/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.com/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Vacation Packages](https://expedia.com/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rental Southeast Missouri, MO ## Search and Compare from Car Companies in Southeast Missouri ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Car Deals in Southeast Missouri \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Southeast Missouri, Missouri, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southeast%20Missouri,%20Missouri,%20United%20States%20of%20America&dpln=6058763&date1=2/22/2026&date2=2/24/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Southeast Missouri, Missouri, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southeast%20Missouri,%20Missouri,%20United%20States%20of%20America&dpln=6058763&date1=2/22/2026&date2=2/24/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Southeast Missouri, Missouri, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southeast%20Missouri,%20Missouri,%20United%20States%20of%20America&dpln=6058763&date1=2/22/2026&date2=2/24/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Southeast Missouri, Missouri, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southeast%20Missouri,%20Missouri,%20United%20States%20of%20America&dpln=6058763&date1=2/22/2026&date2=2/24/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Southeast Missouri [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southeast%20Missouri,%20Missouri,%20United%20States%20of%20America&dpln=6058763&date1=2/22/2026&date2=2/24/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6058763) ## Frequently asked questions ### What happens if I need to cancel my Southeast Missouri car reservation? ### How do I find the best car rental deals in Southeast Missouri with Expedia? ### How old do you have to be to rent a car in Southeast Missouri? ### What do you need to rent a car in Southeast Missouri? ### Can I rent a car for a month or longer in Southeast Missouri? ### Where can I find a Southeast Missouri car rental if I am younger than 25? ### What insurance should I choose for my car rental in Southeast Missouri? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | | | Our second best deal of the day | | | Our third best deal of the day | | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Finding the cheapest car rentals in Southeast Missouri ### **Using our Search Wizard** If the deals that are available on our page do not suit your needs, then enter Southeast Missouri into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Southeast Missouri and provide you with a list of the cheapest options, with no added fees. ### **Renting a car in Southeast Missouri** Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Southeast Missouri. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia. ### **Expected prices in Southeast Missouri** Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book . ### **Flexibility & Cancellation** Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the [Trips](https://www.expedia.com/trips) portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled. ### **We all love being rewarded** [One Key](https://www.expedia.com/welcome-one-key?langid=1033) members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today. ### **Car classes available from Expedia in 2026** The classes of vehicles available will change depending on your chosen location. - [Compact car rentals](https://www.expedia.com/lp/b/car-rental/compact) - [Convertible car rentals](https://www.expedia.com/lp/b/car-rental/convertible) - [Economy car rentals](https://www.expedia.com/lp/b/car-rental/economy) - [Fullsize car rentals](https://www.expedia.com/lp/b/car-rental/fullsize) - [Luxury car rentals](https://www.expedia.com/lp/b/car-rental/luxury) - [Midsize car rentals](https://www.expedia.com/lp/b/car-rental/midsize) - [Mini car rentals](https://www.expedia.com/lp/b/car-rental/mini) - [Minivan rentals](https://www.expedia.com/lp/b/car-rental/minivan) - [Pickup car rentals](https://www.expedia.com/lp/b/car-rental/pickup) - [Premium car rentals](https://www.expedia.com/lp/b/car-rental/premium) - [Sportscar rentals](https://www.expedia.com/lp/b/car-rental/sportscar) - [Standard car rentals](https://www.expedia.com/lp/b/car-rental/standard) - [SUV rentals](https://www.expedia.com/lp/b/car-rental/suv) - [Van rentals](https://www.expedia.com/lp/b/car-rental/van) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Crane Lake Recreation Area ](https://www.expedia.com/Crane-Lake-Recreation-Area-Hotels.0-l6282499-0.Travel-Guide-Filter-Hotels) - [Des Arc Hotels ](https://www.expedia.com/Des-Arc-Hotels.d553248634983251690.Travel-Guide-Hotels) - [Hotels near Walnut Hollow Lake ](https://www.expedia.com/Walnut-Hollow-Lake-Hotels.0-l6282503-0.Travel-Guide-Filter-Hotels) - [Annapolis Hotels ](https://www.expedia.com/Annapolis-Hotels.d6282465.Travel-Guide-Hotels) - [Cabin Rentals in Annapolis ](https://www.expedia.com/Annapolis-Cabins.d6282465-aaCabins.Travel-Guide-Accommodation) - [Cottages in Annapolis ](https://www.expedia.com/Annapolis-Cottages.d6282465-aaCottages.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis ](https://www.expedia.com/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - 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[Pilot Knob Hotels ](https://www.expedia.com/Pilot-Knob-Hotels.d3000008143.Travel-Guide-Hotels) - [Flights from Des Arc ](https://www.expedia.com/lp/flights/553248634983251690/flights-from-des-arc) - [Flights to Annapolis ](https://www.expedia.com/Cheap-Flights-To-Annapolis.d6282465.Travel-Guide-Flights) - [Flights from Greenville ](https://www.expedia.com/lp/flights/553248634983564794/flights-from-greenville) - [Flights from Marquand ](https://www.expedia.com/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Fredericktown ](https://www.expedia.com/lp/flights/55114/flights-from-fredericktown) - [Flights to Fredericktown ](https://www.expedia.com/Cheap-Flights-To-Fredericktown.d55114.Travel-Guide-Flights) - [Flights to Arcadia ](https://www.expedia.com/Cheap-Flights-To-Arcadia.d6346857.Travel-Guide-Flights) - [Flights from Arcadia ](https://www.expedia.com/lp/flights/6346857/flights-from-arcadia) - [Flights to Piedmont ](https://www.expedia.com/Cheap-Flights-To-Piedmont.d3000445413.Travel-Guide-Flights) - 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[K Bridge Recreation Area ](https://www.expedia.com/K-Bridge-Recreation-Area-Annapolis.d6282501.Vacation-Attraction) - [Arcadia Valley Golf Club ](https://www.expedia.com/Arcadia-Valley-Golf-Club-Ironton.d553248621579088852.Vacation-Attraction) - [Arcadia Vacations ](https://www.expedia.com/Arcadia.d6346857.Destination-Travel-Guides) - [Visit Piedmont ](https://www.expedia.com/Piedmont.dx3000445413) - [Visit Ironton ](https://www.expedia.com/Ironton.dx6053585) - [Fort Davidson State Historic Site ](https://www.expedia.com/Fort-Davidson-State-Historic-Site-Ironton.d553248621532648465.Vacation-Attraction) - [Car rentals near Central Fredericktown ](https://www.expedia.com/Car-Rentals-In-Central-Fredericktown.d553248635975850047.Car-Rental-Guide) - [Car rentals near Des Arc ](https://www.expedia.com/Car-Rentals-In-Des-Arc.d553248634983251690.Car-Rental-Guide) - [Car rentals near Annapolis ](https://www.expedia.com/Car-Rentals-In-Annapolis.d6282465.Car-Rental-Guide) - [National Car Rental Rental Cars in Annapolis ](https://www.expedia.com/National-Car-Rental-Car-Rentals-In-Annapolis.d6282465-c42.Car-Rental-Guide-Suppliers) - [Car rentals near Greenville ](https://www.expedia.com/Car-Rentals-In-Greenville.d553248634983564794.Car-Rental-Guide) - [Car rentals near Cobalt ](https://www.expedia.com/Car-Rentals-In-Cobalt.d553248634983153223.Car-Rental-Guide) - [Car rentals near Marquand ](https://www.expedia.com/Car-Rentals-In-Marquand.d553248634983260789.Car-Rental-Guide) - [Car rentals near Fredericktown ](https://www.expedia.com/Car-Rentals-In-Fredericktown.d55114.Car-Rental-Guide) - [Car rentals near Junction City ](https://www.expedia.com/Car-Rentals-In-Junction-City.d553248634983410095.Car-Rental-Guide) - [Car rentals near Arcadia ](https://www.expedia.com/Car-Rentals-In-Arcadia.d6346857.Car-Rental-Guide) - [Car rentals near Piedmont ](https://www.expedia.com/Car-Rentals-In-Piedmont.d3000445413.Car-Rental-Guide) - [Car rentals near Ironton ](https://www.expedia.com/Car-Rentals-In-Ironton.d6053585.Car-Rental-Guide) - [Car rentals near Pilot Knob ](https://www.expedia.com/Car-Rentals-In-Pilot-Knob.d3000008143.Car-Rental-Guide) - [Annapolis Vacation Rentals ](https://www.expedia.com/Annapolis-Vacation-Rentals.d6282465.Travel-Guide-VacationRentals) - [Fredericktown Vacation Rentals ](https://www.expedia.com/Fredericktown-Vacation-Rentals.d55114.Travel-Guide-VacationRentals) - [Arcadia Vacation Rentals ](https://www.expedia.com/Arcadia-Vacation-Rentals.d6346857.Travel-Guide-VacationRentals) - [Piedmont Vacation Rentals ](https://www.expedia.com/Piedmont-Vacation-Rentals.d3000445413.Travel-Guide-VacationRentals) - [Ironton Vacation Rentals ](https://www.expedia.com/Ironton-Vacation-Rentals.d6053585.Travel-Guide-VacationRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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