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Our top choices for Mesopotamia hotels

Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.4 out of 10, Exceptional, (8 reviews)
"Muy lindo Hotel, en las afueras de Concordia, con varias piscinas, estacionamiento, Restaurante (correcto). Recomendado.."
Costa Rica
Pablo
$91 nightly
The price is $91
May 14 - May 15
Mayim Hotel Termal & SPA

La Regina Lodge

La Regina Lodge
4.0 star property
Municipo de Itati
10.0 out of 10, Exceptional, (1 review)
"Excelente pousada, piscina fantástica com visual do rio"
Brazil
Marcos
$61 nightly
The price is $61
Apr 25 - Apr 26
La Regina Lodge

Marriott Corrientes Hotel

Marriott Corrientes Hotel
4.5 star property
Corrientes
10.0 out of 10, Exceptional, (26 reviews)
"Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable."
Australia
Marcus
$116 nightly
The price is $116
Apr 26 - Apr 27
Marriott Corrientes Hotel

Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.6 out of 10, Excellent, (376 reviews)
"Hotel excelente "
Brazil
Ivon
$65 nightly
The price is $65
Apr 19 - Apr 20
Hathor Concordia

La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
4.0 star property
Corrientes
9.2 out of 10, Wonderful, (68 reviews)
"Todo excelente "
Mexico
Arturo Oscar
$89 nightly
The price is $89
Apr 30 - May 1
La Alondra Casa De Huéspedes

Turismo Hotel Casino

Turismo Hotel Casino
2.5 star property
Corrientes
8.8 out of 10, Excellent, (6 reviews)
"Boa infraestrutura, e localização!"
Brazil
D. Omar
$102 nightly
The price is $102
Apr 20 - Apr 21
Turismo Hotel Casino

Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (94 reviews)
"La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto."
United States
Fernando
$75 nightly
The price is $75
Apr 22 - Apr 23
Club Valle Termal Resort

Estancia Iberá

Estancia Iberá
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (1 review)
"we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. "
Canada
orit
$182 nightly
The price is $182
Apr 16 - Apr 17
Estancia Iberá

Nandereta Lodge

Nandereta Lodge
2.5 star property
Colonia Carlos Pellegrini
$282 nightly
The price is $282
Apr 17 - Apr 18
Nandereta Lodge

Hotel Rio

Hotel Rio
3.0 star property
Chajarí
8.8 out of 10, Excellent, (11 reviews)
"Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos."
Argentina
SANTIAGO
$84 nightly
The price is $84
Apr 16 - Apr 17
Hotel Rio

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (33 reviews)
"Great location and friendly, accommodating staff. "
United States
Michael
$109 nightly
The price is $109
Apr 25 - Apr 26
Maran Suites & Towers - Hotel & Spa

Posada Che Teindy

Posada Che Teindy
2.5 star property
Colonia Carlos Pellegrini
10.0 out of 10, Exceptional, (1 review)
"La posada estaba bien limpia y mantenida tal cual sale en las fotos Sería bueno que le hicieran una piscina ya que desde el mediodía hasta las cuatro de la tarde no hay mucho que hacer debido al calor Gracias "
Mexico
Ricardo
$133 nightly
The price is $133
Apr 17 - Apr 18
Posada Che Teindy

Bungalows Mexico

Bungalows Mexico
2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (13 reviews)
"Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. "
Brazil
Eduardo
$53 nightly
The price is $53
Apr 19 - Apr 20
Bungalows Mexico

Costarenas Hotel & Spa

Costarenas Hotel & Spa
3.5 star property
Colon
8.8 out of 10, Excellent, (63 reviews)
"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"
Argentina
Lisette
$117 nightly
The price is $117
Apr 16 - Apr 17
Costarenas Hotel & Spa

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
3.0 star property
Federacion
8.6 out of 10, Excellent, (13 reviews)
"good for a 1 night stay"
Canada
Chase
$55 nightly
The price is $55
Apr 20 - Apr 21
Hotel y Spa Termas del Este

Complejo La Loma

Complejo La Loma
3.0 star property
Federacion
8.4 out of 10, Very Good, (6 reviews)
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Canada
Logan
$39 nightly
The price is $39
Apr 23 - Apr 24
Complejo La Loma

Intersur Colon

Intersur Colon
3.0 star property
Colón
8.0 out of 10, Very Good, (8 reviews)
"Is ok "
United States
Carla
$85 nightly
The price is $85
Apr 20 - Apr 21
Intersur Colon

Pinares del Norte

Pinares del Norte
2.0 star property
Federación
$97 nightly
The price is $97
Apr 23 - Apr 24
Pinares del Norte

Donsuites Apart Hotel

Donsuites Apart Hotel
3.0 star property
Corrientes
8.6 out of 10, Excellent, (108 reviews)
"Loved this place, super clean, and the staff were very nice and helpful😍"
United States
Nora
$72 nightly
The price is $72
Apr 17 - Apr 18
Donsuites Apart Hotel

Agustín 1 Apart

Agustín 1 Apart
4.0 star property
Parana
8.8 out of 10, Excellent, (5 reviews)
"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."
Brazil
Jose rodrigo kallas
$59 nightly
The price is $59
Apr 16 - Apr 17
Agustín 1 Apart
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Mesopotamia

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Stay near popular Mesopotamia attractions

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

Top Mesopotamia Hotel Reviews

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Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Stunning National Parks: Mesopotamia is home to breathtaking national parks, perfect for hiking and wildlife exploration.
  • Outdoor Adventures: Engage in diverse outdoor activities like birdwatching and yoga sessions amidst scenic beauty.
  • Rich Cultural Experiences: Immerse yourself in local culture through private tours and unique shopping hotspots.
  • Romantic Getaways: The enchanting landscapes make it an ideal destination for a romantic retreat.
  • Comfortable Accommodations: Enjoy a range of hotels catering to all needs, ensuring a memorable stay.

Find great hotels near Mesopotamia

Discover the charm of Mesopotamia, Argentina, where a variety of hotels cater to every traveler's needs. Whether you're seeking family-friendly accommodations or a cozy retreat, you'll find the perfect spot to unwind. From luxurious amenities to convenient locations, the best hotels in Mesopotamia offer exceptional service and comfort for a memorable stay. Explore the diverse options available and make your vacation truly special in this enchanting region.

  • El Tránsito Hotel Boutique: El Tránsito Hotel Boutique is a charming 3.5-star hotel with a perfect guest rating of 10.0, located 18 miles from Mesopotamia. This family-friendly accommodation is ideal for those traveling with children, offering amenities such as a dedicated arcade game room, a children’s pool, and complimentary cribs. The hotel combines comfort and fun, ensuring that families can enjoy a memorable vacation experience while providing a welcoming atmosphere for all ages.

Where to stay near Mesopotamia

Mesopotamia, Argentina, offers an enchanting blend of adventure and relaxation, perfect for any traveler. Explore the stunning landscapes, indulge in local culture, and uncover shopping hotspots that showcase the region's charm. Discover breathtaking views that will leave you in awe, whether you’re traveling with family or seeking a romantic getaway. With diverse outdoor activities, Mesopotamia promises an unforgettable experience for all who visit.

  • Mercedes: Located 31 miles from Mesopotamia, Mercedes boasts a charming blend of outdoor adventure and family-friendly experiences. The city is renowned for its vibrant outdoor activities, including golfing and water parks that cater to all ages. Visitors are drawn to the local national state park and theme park, offering a perfect backdrop for exploration and fun. While the travel numbers fluctuate throughout the year, the peak seasons in July and December to January provide a lively atmosphere, making it an ideal time to experience the local culture and community.
  • Concepción: Situated 22 miles from Mesopotamia, Concepción is a scenic city that captivates visitors with its natural beauty and outdoor adventures. Known for its stunning landscapes, the area is perfect for those seeking an adventurous getaway. The local national and natural parks present opportunities for hiking and wildlife observation, making it a haven for nature lovers. With steady visitor numbers throughout the year, peak travel times in April, July, and September ensure a vibrant community atmosphere, inviting travelers to immerse themselves in the local scenery and outdoor pursuits.
  • Uguay: This quaint village lies 17 miles from Mesopotamia and offers a peaceful retreat for those looking to escape the hustle and bustle. Uguay attracts seasonal visitors, particularly peaking in January, March, and November, who come to enjoy the serenity of its natural parks. The village’s proximity to stunning landscapes makes it an excellent base for exploring the surrounding natural beauty. Though quieter compared to its neighboring cities, Uguay provides a unique charm and an authentic experience of rural Argentine life.

Things to do in Mesopotamia

Mesopotamia, Argentina, offers a range of activities for visitors, including birdwatching, hiking, and wildlife exploration. It's an ideal destination for a weekend getaway or a romantic retreat, with opportunities for yoga sessions and private tours. History lovers will also find plenty to appreciate in this captivating region, making it a perfect spot for diverse interests and memorable experiences.

Shopping

In Mesopotamia, Argentina, visit the Shopping del Este for a modern mall experience featuring diverse stores and dining options. For a more local vibe, explore the Feria de Artesanos, a vibrant market offering handmade crafts and unique souvenirs that showcase the region's culture.

Recreation

In Mesopotamia, Argentina, the Termas de Río Hondo offers rejuvenating thermal baths and spa services amidst beautiful landscapes. Enjoy yoga sessions and nature walks at wellness retreats, while savoring local cuisine focused on health and nutrition for a refreshing escape.

Adventure

Explore the Iguazú National Park, where stunning waterfalls and lush rainforest await. Experience thrilling jungle treks and wildlife spotting, or take a boat ride for an exhilarating view of the falls. Don't miss the chance to visit the nearby Jesuit Ruins for a glimpse into the region's history.

Nightlife

In Mesopotamia, Argentina, the nightlife is vibrant with venues like the lively La Casona, known for its upbeat music and dancing. Enjoy local flavors at El Mercado, where you can savor delicious dishes while soaking in the lively atmosphere. Don't miss the cozy bars scattered throughout the area for a relaxed evening.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mesopotamia are October, where the prices are slightly lower. This is in comparison to February and July to August, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Mesopotamia about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your preferences, such as budget, desired location, and hotel type. For instance, selecting the Eco-certified option will show you sustainable and environmentally friendly hotels currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package deal.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a variety of attractions for tourists seeking scenic beauty and outdoor adventures. The area is renowned for its national parks, providing ample opportunities for exploration and adventure. Whether you're looking for breathtaking landscapes or thrilling activities, Mesopotamia's local points of interest cater to every traveler's desire for an unforgettable experience.

  • Portal Carambola: Located 14 miles from Mesopotamia, this national park offers stunning scenery, thrilling outdoor adventures, and a chance to immerse yourself in nature's beauty, making it a perfect destination for adventure seekers and nature lovers alike.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and June. June is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.7°C)Light RainSunnyHighAverage
February77.7°F (25.4°C)Light RainMostly SunnyAverageSlightly High
March72.9°F (22.7°C)Light RainMostly SunnyHighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyLowSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageSlightly Low
November72.3°F (22.4°C)Light RainSunnyHighAverage
December77.0°F (25.0°C)Light RainSunnyAverageAverage

The nearest major airports for your trip to Mesopotamia

Traveling to Mesopotamia, Argentina can be accomplished via several major airports. ASUncion (ASU-Silvio Pettirossi Intl.) is 234 miles away, with nearby hotel options like the 4-star Factoria Hotel and Gran Bourbon Hotel Asunción, both offering shuttle services. Posadas (PSS-Libertador General Jose de San Martin) is located 138 miles from Mesopotamia, with hotels such as La Mision Posadas Hotel providing transportation to the airport. Closer still is RESistencia (RES-Resistencia Intl.), just 113 miles away, where you can find the Amérian Hotel Casino Gala and Gala Hotel y Convenciones, both conveniently located for airport access.