Luxury Hotels in Missouri from $110

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Pick from 414 Missouri Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Royal Sonesta Chase Park Plaza St. Louis

4.5 star property
Central West End
  • 3 restaurants
  • Poolside bar
  • Concierge services
9.0 out of 10, Wonderful, (1005)
Sophisticated comfort defines this Central West End landmark hotel. Guests rave about the immaculate seasonal outdoor pool, exceptional staff service, and well-appointed fitness center. Savor culinary delights at three distinctive restaurants before retiring to premium pillowtop beds with designer touches.
$179 nightly
The price is $211
Nov 30 - Dec 1
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
  • 6 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
8.4 out of 10, Very Good, (1005)
Sophisticated relaxation awaits at this luxury hotel. Ara spa offers indulgent massages, facials, and hydrotherapy treatments. After pampering sessions, guests can enjoy multiple dining venues, soak in 2 hot tubs, or lounge by the poolside bar for an extraordinary escape.
$157 nightly
The price is $184
Dec 7 - Dec 8
Total with taxes and fees
Ameristar Casino Resort and Spa

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
  • 2 restaurants
  • Concierge services
9.2 out of 10, Wonderful, (551)
Spa indulgence awaits at this Clayton luxury retreat where deep-tissue massages, aromatherapy, and body wraps create a haven of relaxation. Steps from Washington University, the hotel features plush bedding, designer toiletries, and impeccable service from staff renowned for their attentiveness.
$469 nightly
The price is $548
Nov 28 - Nov 29
Total with taxes and fees
The Ritz-Carlton, St. Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
  • Full-service spa
  • Poolside bar
  • Concierge services
9.4 out of 10, Exceptional, (1002)
Lavish indulgence defines this downtown St. Louis retreat. The full-service spa offers aromatherapy, body wraps, and facials in 12 treatment rooms, while the stunning outdoor pool provides heavenly relaxation with attentive service. Immaculate rooms feature designer toiletries and soaking tubs.
$425 nightly
The price is $497
Nov 29 - Nov 30
Total with taxes and fees
Four Seasons Hotel St Louis

Moberly Inn and Suites

2.5 star property
Moberly
  • 2 restaurants
  • Poolside bar
  • Concierge services
5.0 out of 10, (172)
Moberly Inn and Suites

Clayton Plaza Hotel & Extended Stay

3.5 star property
Clayton
  • 24-hour gym
  • Indoor pool
8.8 out of 10, Excellent, (3013)
Sauna sessions and serene pool moments define luxury at this elegant Clayton hotel. Premium pillowtop beds cradle guests in comfort while the 24-hour fitness center maintains wellness routines. Mornings begin with complimentary gourmet breakfast featuring made-to-order specialties.
$94 nightly
The price is $110
Nov 30 - Dec 1
Total with taxes and fees
Clayton Plaza Hotel & Extended Stay

The Westin St. Louis

4.5 star property
Downtown St. Louis
  • Concierge services
8.6 out of 10, Excellent, (1009)
Sophisticated comfort awaits in this downtown sanctuary. Premium Italian cuisine at Quattro restaurant complements luxuriously appointed rooms featuring deep soaking tubs and pillowtop beds draped in down comforters. Located just 2 minutes from Stadium Station, this refined retreat balances urban convenience with indulgent tranquility.
$118 nightly
The price is $138
Dec 7 - Dec 8
Total with taxes and fees
The Westin St. Louis

Cliffs Resort Table Rock Lake

4.0 star property
Branson
  • Hot tub
  • Outdoor pool
9.2 out of 10, Wonderful, (967)
Lakeside indulgence awaits at this upscale Branson retreat. Guests relax in spacious condos with fireplaces, fully equipped kitchens, and private furnished balconies overlooking Table Rock Lake. A seasonal outdoor pool, hot tub, and children's pool complete the serene entertainment district setting.
Cliffs Resort Table Rock Lake

Argosy Casino & Hotel

4.0 star property
Riverside
  • 6 restaurants
8.2 out of 10, Very Good, (1086)
Spacious rooms with pillowtop beds create a peaceful sanctuary amid exciting casino action. Six diverse restaurants and a welcoming outdoor patio with fire pits offer delightful spaces to unwind after trying your luck at gaming tables or slots.
$109 nightly
The price is $121
Nov 27 - Nov 28
Total with taxes and fees
Argosy Casino & Hotel

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
Downtown St. Louis
  • Hot tub
  • Indoor pool
9.4 out of 10, Exceptional, (3271)
Sumptuous comfort awaits at this downtown sanctuary steps from the Gateway Arch. Morning buffets transition to evening receptions while the indoor pool, hot tub, and rooftop observation deck create perfect relaxation zones after exploring nearby attractions.
$128 nightly
The price is $150
Dec 2 - Dec 3
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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