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St. Louis Hotels

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Top St. Louis Neighborhoods for Luxury Hotels

Featured St. Louis Luxury Hotels

See all 265 Hotels in St. Louis
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis
5.0 out of 5.0
4.8 out of 5 (95 reviews)
St Louis for the Great American EclipseThe check-in process for the hotel was fine, and our room was ready as expected. But when we got back to the room after lunch, about three hours later, our luggage had not been delivered to the room. I called down to enquire, and it took another 20 minutes to get our bags. This was very inconvenient. ...
  Aug 22, 2017

$188

$188
Missouri Athletic Club

Missouri Athletic Club

405 Washington Ave, St. Louis
3.5 out of 5.0
3.8 out of 5 (224 reviews)
Nice hotel close to the Arch, publi transportationI went to to SL to watch the eclipse. I found at the hotl everything I needed for my short stay.
  Aug 23, 2017

$115

$115
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (1,609 reviews)
Perfect Great staff. Perfect downtown location. Very clean & updated rooms. We arrived early & they had our room ready with no issue.
  Aug 24, 2017

$149

$149
Super 8 Fairview Heights, St. Louis

Super 8 Fairview Heights, St. Louis

45 Ludwig Dr, Fairview Heights
2.0 out of 5.0
3.8 out of 5 (88 reviews)
Nice for a pit stop on a road trip My fiancé and I need a place to rest for the night, the bed was extremely comfortable. The AC was efficient, worth the money and it was close to a lot of places to eat. The room was clean, more than enough towels, the tv was good and had good channels. The paint on the wall was chipped in a few places ...
  Jul 13, 2017

$69

$69
River City Casino & Hotel

River City Casino & Hotel

777 River City Casino Blvd, St. Louis
4.0 out of 5.0
4.5 out of 5 (246 reviews)
Very nice and fair priceThe staff was great, rooms very nice and so comfy😊
  Aug 23, 2017

$118

$118
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles
4.5 out of 5.0
4.5 out of 5 (298 reviews)
A small get away for over-night. Resort was perfect for over-night stay. Not a gambler, but enjoy St. Charles old town for shops.
  Aug 23, 2017

$149

$149
La Quinta Inn & Suites Collinsville

La Quinta Inn & Suites Collinsville

6 Gateway Dr, Collinsville
2.5 out of 5.0
3.9 out of 5 (161 reviews)
Close to Cahokia State ParkEasy on/ off to interstate and close to restaurants. Also just across from St Louis and the Gateway Arch. Convenient!
  Aug 23, 2017

$77

$77
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis
3.0 out of 5.0
4.7 out of 5 (856 reviews)
One of the best hotels we've ever stayed at!Not one complaint for this hotel! Location was a block away from Ballpark village and the Arch. Our room was modern and clean. We received free continental breakfast each morning consisting of eggs, pancakes, bagels, fruit, and more! At night we received 3 free drinks along with basically a free ...
  Aug 23, 2017

$130

$130
DoubleTree by Hilton St. Louis - Chesterfield

DoubleTree by Hilton St. Louis - Chesterfield

16625 Swingley Ridge Rd, Chesterfield
3.5 out of 5.0
4.2 out of 5 (161 reviews)
Great location and great health club!!!Great staff that went out of their way to make my stay enjoyable!!
  Aug 4, 2017

$89

$89
The Hotel Majestic St. Louis

The Hotel Majestic St. Louis

1019 Pine St, St. Louis
4.0 out of 5.0
3.9 out of 5 (462 reviews)
Great old hotel with a easy walk to Bush stadium Very nice old hotel in downtown St Louis with surprisingly large rooms for a old hotel. Very friendly staff and close enough to walk to Bush stadium. Parking at the hote is limited (I knew this before booking the hotel for the weekend) but the lot across the street is safe and well lit.
  Aug 18, 2017

$116

$116
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis
4.5 out of 5.0
4.6 out of 5 (112 reviews)
Elegant hotel near Washington UniversityThe exterior of this Ritz Carlton is rather bland but the interior is beautiful! There are crystal chandeliers everywhere in the first floor public spaces making the rooms sparkle. And the newly remodeled upper floors are stunning in shades of blue. The staff could not have been more helpful, our ...
  Jul 10, 2017

$249

$249
Airport Plaza Inn & Conference Center

Airport Plaza Inn & Conference Center

4534 Long Road, Bridgeton
3.0 out of 5.0
3.1 out of 5 (749 reviews)
Nice and clean for the priceVery nice and not a lot of money. Comfortable with an awesome hot breakfast. Very clean. Under construction but didn't affect anything.
  Aug 24, 2017

$69

$69
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis
4.0 out of 5.0
4.6 out of 5 (900 reviews)
Across the street from ballpark If your going to a ball game, this is the place to stay.
  Aug 23, 2017

$129

$129
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
4.0 out of 5 (565 reviews)
clayton HotelHotel parking confusing- better signage needed esp: ramp under construction Elevators confusing- direction to pool not well signed. Support staff friendly Desk staff needs work.
  Aug 23, 2017

$109

$109
The Chase Park Plaza

The Chase Park Plaza

212 N Kingshighway, St. Louis
4.5 out of 5.0
4.4 out of 5 (612 reviews)
Excellent service and locationEnjoyed the hotel and its great location. Found the continental breakfast well worth the price.
  Aug 23, 2017

$189

$189
Magnolia Hotel St. Louis

Magnolia Hotel St. Louis

421 N 8th St, St. Louis
4.0 out of 5.0
4.3 out of 5 (192 reviews)
Very nice hotel. Great downtown location. It has an electric car charging station.
  Aug 19, 2017

$118

$118
The Wildwood Hotel, BW Premier Collection

The Wildwood Hotel, BW Premier Collection

2801 Fountain Pl, Wildwood
3.0 out of 5.0
4.4 out of 5 (603 reviews)
Loved this hotel!Great hotel with great staff! The room was very clean. The bed was incredibly comfortable. The breakfast each morning was wonderful! And the staff were very attentive!
  Aug 24, 2017

$86

$86
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis
4.0 out of 5.0
4.2 out of 5 (655 reviews)
Wonderful staff and great for familiesMy 2 children (8 and <1) stayed here for a night. The staff was very caring and helpful! Joel was amazing and made dinner time with 2 kiddos a breeze! The indoor light show and the new fire and light show outside were great entertainment for all of us! Will definitely stay here again!
  Aug 17, 2017

$116

$116
St. Louis City Center Hotel

St. Louis City Center Hotel

400 S 14th St, St. Louis
3.5 out of 5.0
3.6 out of 5 (844 reviews)
Close to Arch and resterauntsNice place downtown, not far fro Arch and stadium, valet was nice.
  Aug 23, 2017

$103

$103
The Cheshire

The Cheshire

6300 Clayton Rd, Richmond Heights
4.0 out of 5.0
4.0 out of 5 (386 reviews)
Great for visiting Forest Park attractionsLittle things enhanced our stay. There was a children's scavenger hunt with a nice prize. (We never got around to completing the adult edition.) Clean towels were always available at the pool. We had eggs benedict for breakfast one morning. Poolside furniture was very comfortable, Mattresses were ...
  Aug 5, 2017

$143

$143
Map

Recently booked Luxury Hotels in St. Louis

Clayton Plaza Hotel
3.5 out of 5.0
Last booking: 3 minutes ago
Drury Inn St. Louis St. Peters
3.0 out of 5.0
Last booking: 7 minutes ago
Crowne Plaza Riverfront at the Arch
3.5 out of 5.0
Last booking: 7 minutes ago
Holiday Inn St Louis SW - Route 66
3.0 out of 5.0
Last booking: 8 minutes ago
Motel 6 Maryland Heights, MO
2.0 out of 5.0
Last booking: 18 minutes ago
Homewood Suites by Hilton St. Louis-Chesterfield
3.0 out of 5.0
Last booking: 21 minutes ago
Hyatt Regency St. Louis at The Arch
4.0 out of 5.0
Last booking: 32 minutes ago
Courtyard by Marriott St. Louis Downtown West
3.0 out of 5.0
Last booking: 36 minutes ago
Days Inn St. Louis Westport MO
2.5 out of 5.0
Last booking: 36 minutes ago

When you'll take your luxury hotel with a side of exciting city life, you've found your niche in St. Louis. As one of the most intriguing travel stops for people who want to soak up the energy of a big city, St. Louis always impresses. Exquisite eats, intriguing sites, and some of the world’s most stunning photo opportunities: these are just some of the reasons to take a trip to St. Louis. Of course, you'll stay at a luxury hotel! Sampling the finer things in life is just your speed. While you're here, you'll also enjoy the most popular performances, devour fabulous food, and marvel at the most popular monuments and landmarks . Book your elegant hotel in St. Louis on Expedia.com today and start your vacation off on the right (well-dressed) foot.

Booking St. Louis Vacations

If you need any proof that St. Louis is full of wonderful things to do, you should know that 315,685 people love it enough to have set down roots. No matter what brings you to St. Louis, the destination always delivers. St. Louis is full of outstanding hotels as well as fantastic food, so you can count on a spectacular stay. Book well in advance to get a room with a view!

Any 5-star getaway is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your vacation on Expedia.com, the world is your oyster. Thanks to our hotel deals, you'll still have plenty of cash for the most compelling and captivating adventures. After many hours of seeing the sights, your luxury accommodation awaits. Take advantage of amenities like an oversized bathtub or hot tub before the day is over. The luxury rooms and suites in St. Louis will render you into a state of tranquility in the blink of an eye.

Luxury Hotels in St. Louis

It's that time; you're ready to get swept away in The Gateway to the West, and Expedia.com is here to save the day. Search through the wealth of real traveler reviews on dozens of hotels and then book your ideal room in minutes. 5-Star hotels treat you right, offering things like concierge services and private fireplaces. Many 5-star accommodations in St. Louis even feature gigantic suites, and it's not uncommon to find reinvigorating spa treatments in your hotel. Use our easy booking widget to choose the ideal 5-star hotel in St. Louis, and prepare for the trip of a lifetime!