A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Vacation Rentals

Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Panama City vacation rentals

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

1. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
$135 nightly
The price is $151
Oct 5 - Oct 6
Total with taxes and fees
La Isabela Suites
A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

2. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very good, (135 reviews)
"Great location and very nice hotel. Great pool and restaurants."
Canada
Howard
$184 nightly
The price is $189
Sep 30 - Oct 1
Total with taxes and fees
Yoo Panamá by Boutique Apartments
A rooftop pool with a city view, lounge chairs, and a clear sky.

3. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (385 reviews)
"Nice place good location"
United States
Rame
$152 nightly
The price is $167
Oct 3 - Oct 4
Total with taxes and fees
Corporate Stays Arcadia | Executive Furnished Apartments
A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

4. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (583 reviews)
"Restaurants nearby are nice. Room was quiet which is an accomplishment for Panama City."
United States
Robert
$92 nightly
The price is $102
Sep 29 - Sep 30
Total with taxes and fees
Torres de Alba Hotel & Suites
A multi-story building with balconies, large windows, and a clear blue sky.

5. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (203 reviews)
"Great food and location"
United States
James
$170 nightly
The price is $187
Oct 13 - Oct 14
Total with taxes and fees
Las Clementinas
A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

6. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (374 reviews)
"Great stay!!!!"
United States
fitz
$141 nightly
The price is $154
Sep 30 - Oct 1
Total with taxes and fees
Boutique Apartments Panama
A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

7. Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
8.4 out of 10, Very good, (17 reviews)
"I love the place and it was in walking distance to many places if you want a uber"
United States
Denise
$70 nightly
The price is $78
Oct 7 - Oct 8
Total with taxes and fees
Modern Apartments at The Gray Prime Location
A rooftop pool with lounge chairs and a cityscape view.

8. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (767 reviews)
"Great hotel, good breakfast friendly staff"
United States
Kitania
$107 nightly
The price is $118
Sep 30 - Oct 1
Total with taxes and fees
Marriott Executive Apartments Panama City, Finisterre
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

9. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
$167 nightly
The price is $200
Sep 30 - Oct 1
Total with taxes and fees
Living 73 Panamá by Boutique Apartments
An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

10. Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (11 reviews)
"This property was much more than I expected, room and property was clean, lots of restaurants around the area, easy to get around, will certainly be back at this property"
United States
Kareem
$63 nightly
The price is $69
Sep 29 - Sep 30
Total with taxes and fees
Modern Design Apartments near Sortis
A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

11. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
8.4 out of 10, Very good, (6 reviews)
"Good price for the location."
United States
Mark
$124 nightly
The price is $136
Oct 15 - Oct 16
Total with taxes and fees
Yoo Panama Luxury Ocean View Apartment
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

12. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (234 reviews)
"very nice place to stay"
United States
purabi
$175 nightly
The price is $192
Oct 1 - Oct 2
Total with taxes and fees
Boutique Apartments Panamá Coco del Mar
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

13. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
$120 nightly
The price is $133
Oct 4 - Oct 5
Total with taxes and fees
La Résidence Panamá
A modern outdoor swimming pool with a clear view of a tall building in the background.

14. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (35 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
$155 nightly
The price is $170
Sep 29 - Sep 30
Total with taxes and fees
Dovle Residences by HMS-Preferred Member
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

15. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (106 reviews)
"Amazing location and comfort"
United States
Ruben
$100 nightly
The price is $110
Oct 1 - Oct 2
Total with taxes and fees
Casco View Life Residences
A modern living room with a sofa, a coffee table, a TV, and a dining area with chairs and a table.

16. La Moderna Downtown Nights by Wynwood

La Moderna Downtown Nights by Wynwood
3.0 star property
Casco Viejo
7.2 out of 10, Good, (51 reviews)
"Great place"
United States
Ross
$93 nightly
The price is $102
Oct 4 - Oct 5
Total with taxes and fees
La Moderna Downtown Nights by Wynwood
A tall, modern skyscraper with a grid-like facade and numerous windows.

17. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended."
United States
Andre
$77 nightly
The price is $84
Oct 5 - Oct 6
Total with taxes and fees
Luxury City View Apartments at Worldwide
A bedroom with a wooden ceiling, a bed with a headboard, bedside lamps, and an air conditioning unit.

18. Modern apartment in the city center

Modern apartment in the city center
2.0 star property
Bella Vista
$82 nightly
The price is $90
Oct 1 - Oct 2
Total with taxes and fees
Modern apartment in the city center
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

19. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
$204 nightly
The price is $224
Sep 29 - Sep 30
Total with taxes and fees
Wanders Panama by Boutique Apartments
A modern hotel room with a large bed, a desk, and a view of the city through floor-to-ceiling windows.

20. The Hub Modern Apartments by Wynwood

The Hub Modern Apartments by Wynwood
3.0 star property
San Francisco
The Hub Modern Apartments by Wynwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

10/10 Excellent
"We had a nice clean room, the breakfast buffet was very good and switched up every morning, the pool and pool bar was a great place to hang out at, and the staff was truly amazing"
Robert Hawk 5-night trip
Posted 9 hours ago
Hospedium Princess Hotel Panama

Find out more about Panama City

Everything you need to know about Panama City vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama City vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama City vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama City vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama City. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama City in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama City rentals

At Expedia, we put the best Panama City vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama City vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

What's the top vacation rental in Panama City?

Downtown Villa with Private Pool & Bar: This Panama City vacation home rental offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. Some other top choices in Panama City are Casa Randa: 6 Ensuite Bedrooms near the Panama Canal and Luxury 3BR Pool, SPA & Golf Resort Near Canal 302.

How many vacation rentals are there in Panama City?

With 59 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include Interoceanic Canal Museum and Biomuseo, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.