Penonome Vacation Rentals from $95: Search Short-Term Rentals

Q: What are some of the best vacation home rentals in Penonome?

Beachfront Villa in Decameron : This vacation home rental near Penonome offers a hot tub, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

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Our top choices for Penonome vacation rentals

Vacation Home in Penonomé

Katrina S.

$95 nightly

Dec 10 - Dec 11

Total with taxes and fees

Cabin in Los Llanitos

"Una cabaña espectacular, con comodidad y vistas de ensueño. La propiedad es tan encantadora que no te dan ganas de irte por la paz que se respira y lo acogedora que es. Sin duda lo recomiendo y volvere muy pronto. Algo a tomar en cuenta es que para llegar a la cabaña debe ser en un auto 4x4 por un tramo del camino que no esta asfaltado ( nada tampoco muy grave y vale a pena por el lugar) ya que un auto pequeño tendria mucha mas dificultad. Lo recomiendo altamente y agradezco la amabilidad del...

Emmy

$162 nightly

Jan 6 - Jan 7, 2026

Total with taxes and fees

Vacation Home in Anton Valley

$118 nightly

Dec 11 - Dec 12

Total with taxes and fees

Cabin in El Valle de Anton

Bart

$91 nightly

Dec 10 - Dec 11

Total with taxes and fees

Condo in Rio Hato

Brandon H.

$152 nightly

Dec 11 - Dec 12

Total with taxes and fees

Apartment in Río Hato

Irving R.

$160 nightly

Dec 10 - Dec 11

Total with taxes and fees

Villa in Anton Valley

t v.

$221 nightly

Dec 11 - Dec 12

Total with taxes and fees

Apartment in Valle de Anton

$109 nightly

Dec 14 - Dec 15

Total with taxes and fees

Villa in Río Hato

Tamara N.

$249 nightly

Dec 10 - Dec 11

Total with taxes and fees

Apartment in rio hato

$201 nightly

Dec 10 - Dec 11

Total with taxes and fees

Vacation Home in El Valle de Antón

$279 nightly

Dec 10 - Dec 11

Total with taxes and fees

Apartment in Coclé

Sean T.

$314 nightly

Dec 10 - Dec 11

Total with taxes and fees

Apartment in El Chirú

Jose F.

$205 nightly

Dec 10 - Dec 11

Total with taxes and fees

Villa in Río Hato

Keith O.

$178 nightly

Dec 14 - Dec 15

Total with taxes and fees

Apartment in panama

$201 nightly

Dec 10 - Dec 11

Total with taxes and fees

Apartment in Río Hato

$201 nightly

Dec 10 - Dec 11

Total with taxes and fees

Condo in Rio Hato

$312 nightly

Dec 11 - Dec 12

Total with taxes and fees

Apartment in rio hato

$233 nightly

Dec 10 - Dec 11

Total with taxes and fees

Apartment in Río Hato

$201 nightly

Dec 10 - Dec 11

Total with taxes and fees

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Top Penonome Hotel Reviews

Hotel La Compania Del Valle

10/10 Excellent

"After the changes to the facilities and the new chain I have to say is a great luxury hotel"

Nomada Republic Hotel El Valle

10/10 Excellent

"Unique property, uniquely situated - on the mountain, somewhere in the "hair" of la India Dormida. The views, the quiet, and the isolation would be hard to match. This gets all my 5 stars. Stayed in a mountain-view Queen studio. The rooms are clean but basic and small - and as advertised (as a container-based hotel). Very little by way of amenities or service. If you arrive with the mindset of a basic camp lodge, with a very comfortable Queen bed. The views and isolation should more than make up for the spartan accommodation. If you arrive with the mindset of a standard hotel room, you will be disappointed. But the views and isolation should more than make up for it. The staff, especially Ariel, are very helpful. And mostly leave you to your devices unless you need them. Should be noted that the breakfast is in a separate restaurant building, Las Nubes, that is a 2 minute walk away — but it's a very steep walk up the very steep mountain road that also leads to the hotel. Several guests with cars simply drove up. I chose the exercise. The restaurant is open for lunch and dinner. While there is more dining variety driving down into the valley and El Valle; the drive back up the mountain when dark can be daunting. So having Las Nubes as a late dining option is good. If you hike up the La India Dormida trail, at its peak you can look across and see Las Nubes in the distance. But with some dodgy descent and climbing between you both. "

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Everything you need to know about Penonome vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Penonome vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Penonome vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Penonome vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Penonome. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Penonome in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $95 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Penonome rentals

At Expedia, we put the best Penonome vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Penonome rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Penonome vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Penonome. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in Penonome?

Yes, you can find vacation rentals close to the most popular sights in Penonome, or you can go with a more remote option if you want a relaxing place to stay. Penonome is known for its parks and restaurants. Make sure you have time to check out the museums while you're in the area.

What are some of the best vacation home rentals in Penonome?

Beachfront Villa in Decameron: This vacation home rental near Penonome offers a hot tub, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Penonome?

Explore the area and family-friendly sights such as Serpentarium, or get out into nature at a spot like 8 de Diciembre Park. Penonomena History and Tradition Museum and Playa Blanca are a couple of places you'll find in the larger area.

What’s a vacation rental in Penonome like?

Vacation rentals are private properties you can book for short or long periods in Penonome. Vacation rentals provide amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for small groups.

Penonome Vacation Rentals

Check prices for these dates

Our top choices for Penonome vacation rentals

Vacation Home in Penonomé

Cabin in Los Llanitos

Vacation Home in Anton Valley

Cabin in El Valle de Anton

Condo in Rio Hato

Apartment in Río Hato

Villa in Anton Valley

Apartment in Valle de Anton

Villa in Río Hato

Apartment in rio hato

Vacation Home in El Valle de Antón

Apartment in Coclé

Apartment in El Chirú

Villa in Río Hato

Apartment in panama

Apartment in Río Hato

Condo in Rio Hato

Apartment in rio hato

Apartment in Río Hato

Find vacation rentals that suit your style

Top Penonome Hotel Reviews

Hotel La Compania Del Valle

The Golden Frog Inn

Hotel Las Catalinas Antón

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

Hotel Riu Playa Blanca - All Inclusive

Nomada Republic Hotel El Valle

Mi Casa Asi de Grande

Casa Madre Tierra

Grand Decameron Panama, A Trademark All Inclusive Resort

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