Title: South Carolina Midlands, SC Inns from $75 | Expedia.com

[South Carolina Midlands Travel Guide](https://expedia.com/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.com/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.com/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.com/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.com/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[Car Rentals in South Carolina Midlands](https://expedia.com/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.com/South-Carolina-Midlands.d6057938.Destination-Travel-Guides)

![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Next weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In one month

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

No exact matches found, but these alternatives could be just right

## Recommended hotels in South Carolina Midlands

![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds | Free cribs/infant beds, free rollaway beds, bed sheets](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/949b4986.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/5cc0357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Latta by IHG

[](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information)

Latta

9.4/10

Exceptional

(553 reviews)

"Front desk is amazing! Rooms are clean and quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

$118 nightly

$129 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru By Hilton Santee

[](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

Santee

9.2/10

Wonderful

(724 reviews)

"Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

$112 nightly

$124 total

Feb 24 - Feb 25

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Santee

[](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

Santee

9.8/10

Exceptional

(1,006 reviews)

"Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marcia

$121 nightly

$134 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/c321176c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/2b6111ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/b23b9566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/f9325683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn on the Square, an Ascend Collection Hotel

[](https://www.expedia.com/Greenwood-Hotels-Inn-On-The-Square.h1212931.Hotel-Information)

Uptown Greenwood

9.2/10

Wonderful

(716 reviews)

"It was a very clean and beautiful lace to stay. We were there for our honeymoon "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

$106 nightly

$117 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Greenwood-Hotels-Inn-On-The-Square.h1212931.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Florence Center Area

[](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information)

Florence

9.2/10

Wonderful

(1,229 reviews)

"Room was very nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

$101 nightly

$113 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Santee Inn

[](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

Santee

8.8/10

Excellent

(1,002 reviews)

"Nice rooms and very good breakfast items."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephen

$112 nightly

$124 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Santee

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

Santee

8.0/10

Very Good

(1,431 reviews)

"Room were very clean and staff was very helpful. I would stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charolette

$75 nightly

$83 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/a1a27db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/21565fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/16d0ef5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/abbeba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lexington Expo Hotel by IHG

[](https://www.expedia.com/Lexington-Hotels-Lexington-Expo-Hotel-By-IHG.h1823665.Hotel-Information)

Lexington

9.2/10

Wonderful

(1,002 reviews)

"Great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Konrad

$113 nightly

$125 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Lexington-Hotels-Lexington-Expo-Hotel-By-IHG.h1823665.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/2f1f8cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/5f4afc1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard king non smoking | In-room safe, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/b241d6b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/1aef51e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Rock Hill

[](https://www.expedia.com/Rock-Hill-Hotels-Hampton-Inn-Rock-Hill.h21992.Hotel-Information)

Rock Hill

9.2/10

Wonderful

(1,001 reviews)

"We have stayed here several times and it never disappoints! Room is clean, staff very friendly, and they provide a great breakfast!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erma

$89 nightly

$99 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Rock-Hill-Hotels-Hampton-Inn-Rock-Hill.h21992.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/713b3c0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/55a9de69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/0ec38ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, Multiple Beds | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/cff7c686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springhill Suites by Marriott Columbia near Fort Jackson

[](https://www.expedia.com/Columbia-Hotels-Springhill-Suites-By-Marriott-Columbia-Southeast.h91267861.Hotel-Information)

Columbia

9.4/10

Exceptional

(618 reviews)

"Great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Howard

$98 nightly

$109 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-Springhill-Suites-By-Marriott-Columbia-Southeast.h91267861.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9f09eded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/689a1cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

[](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information)

Florence

8.6/10

Excellent

(1,010 reviews)

"Friendly staff, quick check in, nice lobby"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

$118 nightly

$132 total

Feb 19 - Feb 20

Total with taxes and fees

[](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information)

![Outdoor banquet area](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2fa2ba7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2d8379fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2a082860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/22dee554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza North Augusta by IHG

[](https://www.expedia.com/Aiken-Hotels-Crowne-Plaza-North-Augusta.h29853240.Hotel-Information)

North Augusta

8.8/10

Excellent

(865 reviews)

"Great room and great staff. My favorite staycation spot."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

cedric

$132 nightly

$148 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Aiken-Hotels-Crowne-Plaza-North-Augusta.h29853240.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/b50995e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/2db4f7f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/3fbd24c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn by Wyndham Columbia SE / Fort Jackson

[](https://www.expedia.com/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information)

Columbia

7.8/10

Good

(1,004 reviews)

"I really enjoyed our stay , beds were very comfortable we slept like babies. Very quiet place , staff was very helpful and kind. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ranetta Whitton

$82 nightly

$91 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson by Wyndham Florence

[](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

Florence

8.6/10

Excellent

(2,571 reviews)

"Clean rooms, good breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Suman

$67 nightly

$75 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/a93e569b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Florence Downtown

[](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information)

Florence

9.0/10

Wonderful

(1,004 reviews)

"Great location and well maintained property. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

$100 nightly

$112 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/260000/250900/250862/w3837h2560x3y0-51e671c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/260000/250900/250862/w3837h2560x3y0-cd66557b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/260000/250900/250862/w3837h2560x3y0-d38b71cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed with Sofa bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/260000/250900/250862/w3837h2560x3y0-92efb678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Lexington Inn

[](https://www.expedia.com/Columbia-Hotels-Best-Western-Plus-Lexington-Inn.h250862.Hotel-Information)

Downtown Lexington

9.2/10

Wonderful

(1,000 reviews)

"Great stay good price"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeff

$100 nightly

$111 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-Best-Western-Plus-Lexington-Inn.h250862.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356801/6106ae70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356801/25ca9138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356801/78849ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356801/99038ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Columbia Killian Road

[](https://www.expedia.com/Columbia-Hotels-Hampton-Inn-Suites-Columbia-Killian-Road.h31356801.Hotel-Information)

Columbia

9.2/10

Wonderful

(1,031 reviews)

"Great hotel with a convenient location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

vielka

$115 nightly

$129 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-Hampton-Inn-Suites-Columbia-Killian-Road.h31356801.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c5155ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/f2adc30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/eb4d1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information)

Orangeburg

9.2/10

Wonderful

(1,003 reviews)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

$114 nightly

$127 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Santee-I-95

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

Santee

9.6/10

Exceptional

(1,003 reviews)

"Liked the size of the room, the staff and the breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Virginia

$119 nightly

$133 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/47b4af62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/15b3bfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/cef510a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/5bdd7f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Southern Lodge 601

[](https://www.expedia.com/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information)

Orangeburg

2.0/10

(1 review)

"The room smelled. The tub leaked water all over the floor and it didn’t work. There were dead and living bugs on the floor. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Edward

$67 nightly

$74 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03&regionId=6057938&adults=2&lodging=INN&sort=RECOMMENDED&openPlayBack=true)

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## Top South Carolina Midlands Hotel Reviews

![Cambria Hotel Columbia Downtown The Vista](https://images.trvl-media.com/lodging/77000000/76600000/76599300/76599223/e2b9c83a_y.jpg)

### Cambria Hotel Columbia Downtown The Vista

10/10 Excellent

"Room was spotless and very nice. I couldn’t hear anyone in the rooms around us. Staff was excellent, very friendly and helpful! There was no parking but valet took care of us!"

[](https://expedia.com/Columbia-Hotels-Cambria-Hotel-Columbia-Downtown-The-Vista.h76599223.Hotel-Information)

![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg)

### Graduate by Hilton Columbia SC

10/10 Excellent

"The hotel was unique from lobby to room. Exceptionally clean and a fun place to stay. "

[](https://expedia.com/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information)

![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg)

### Hilton Garden Inn Columbia/Harbison

10/10 Excellent

"yes"

[](https://expedia.com/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information)

![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg)

### Park Inn by Radisson Florence, SC

10/10 Excellent

"Very clean. The staff was so friendly and helpful. The breakfast was great!!! I’ll definitely be back "

[](https://expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information)

![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg)

### Howard Johnson by Wyndham Florence

10/10 Excellent

"Room was great and clean, staff friendly and helpful. "

[](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![Wyndham Garden Columbia/Ft. Jackson](https://images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg)

### Wyndham Garden Columbia/Ft. Jackson

10/10 Excellent

"None"

[](https://expedia.com/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information)

![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg)

### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

10/10 Excellent

"Excelent service "

[](https://expedia.com/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information)

![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg)

### La Quinta Inn by Wyndham Columbia SE / Fort Jackson

10/10 Excellent

"I really enjoyed our stay , beds were very comfortable we slept like babies. Very quiet place , staff was very helpful and kind. "

[](https://expedia.com/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information)

![Springhill Suites by Marriott Columbia near Fort Jackson](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/713b3c0a_y.jpg)

### Springhill Suites by Marriott Columbia near Fort Jackson

10/10 Excellent

"Outstanding "

[](https://expedia.com/Columbia-Hotels-Springhill-Suites-By-Marriott-Columbia-Southeast.h91267861.Hotel-Information)

## Find out more about South Carolina Midlands

## South Carolina Midlands Inns information

| Number of reviews | 19,761 |
| ----------------- | ------ |
| Accommodation     | 1 Inns |
| Lowest Price      | $75    |
| Highest Price     | $148   |

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- [Fort Jackson ](https://www.expedia.com/Fort-Jackson-Columbia.d6145263.Vacation-Attraction)
- [Visit Blythewood ](https://www.expedia.com/Blythewood.dx180657)

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