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South San Diego Vacation Rentals

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Vacation Rentals in South San Diego

Beachfront- Gorgeous 4 Bedroom House

Imperial Beach
9.4 out of 10, Exceptional, (92)
"This house was beautiful right on the water in a great area. Beautiful view of the water. Great amenities! Will definitely stay here again!"
United States
Dianna C.
Beachfront- Gorgeous 4 Bedroom House

Sentral Gaslamp Quarter

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (587)
"It was nice stay! "
United States
Chashawna
$171 nightly
The price is $198
Dec 14 - Dec 15
Total with taxes and fees
Sentral Gaslamp Quarter

Kasa Little Italy San Diego

4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (350)
"Beautiful rooms, super clean and very responsive and nice staff!"
United States
Ivona
$252 nightly
The price is $288
Dec 8 - Dec 9
Total with taxes and fees
Kasa Little Italy San Diego

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2.5 star property
Hillcrest
8.4 out of 10, Very Good, (264)
"Overall good place."
United States
Isaac
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

City24 Hotel Little Italy Mission Hills

4.5 star property
Middletown
9.6 out of 10, Exceptional, (104)
"would definitely go back and stay there again "
United States
Kounwick
$174 nightly
The price is $196
Dec 18 - Dec 19
Total with taxes and fees
City24 Hotel Little Italy Mission Hills

Little Italy Inn - Limited Service Apart Hotel

2.5 star property
Downtown San Diego
8.2 out of 10, Very Good, (111)
"Everything was great close to shopping and great dining"
Canada
Wendy
Little Italy Inn - Limited Service Apart Hotel

Coronado Beach Resort

3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (747)
"Booked a year early and was given a room with a parking lot view."
United States
Marie
$188 nightly
The price is $207
Dec 15 - Dec 16
Total with taxes and fees
Coronado Beach Resort

Kasa Gaslamp Quarter San Diego

3.5 star property
Downtown San Diego
8.0 out of 10, Very Good, (151)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
$99 nightly
The price is $113
Dec 18 - Dec 19
Total with taxes and fees
Kasa Gaslamp Quarter San Diego

Oceanfront Beach, Pool, Hot Tub, Pickleball, Movie Theater, Elevator & Golf Cart

Bird Rock
9.6 out of 10, Exceptional, (117)
"Great family time great chef family was very happy great pool play areas wonderful "
United States
Providence M.
Oceanfront Beach, Pool, Hot Tub, Pickleball, Movie Theater, Elevator & Golf Cart

OCEAN VIEWS! New Modern Style House-Great for Groups and Families

Mission Beach
9.6 out of 10, Exceptional, (105)
"Excellent stay. Great host. Perfect location. Couldn't recommend this place more. "
United States
Hayden B.
OCEAN VIEWS! New Modern Style House-Great for Groups and Families

"Entire" Luxury Beach Home Steps from Mission Beach with Hot Tub -Not a Condo!

Mission Beach
9.6 out of 10, Exceptional, (204)
"Everything was great! There is a ton of space, lots of games and amenities, if we come back in a large group again, id love to stay at this property. "
United States
Justin S.
"Entire" Luxury Beach Home Steps from Mission Beach with Hot Tub -Not a Condo!

tourmaline beach studio

Pacific Beach
9.8 out of 10, Exceptional, (521)
"Nice, convenient location, cute little guest house."
United States
Nekeshia S.
$223 nightly
The price is $248
Dec 7 - Dec 8
Total with taxes and fees
tourmaline beach studio

Open Dec 27-31/Jan 4 -9/Pool/Views/LM Deals!!

Bird Rock
9.4 out of 10, Exceptional, (25)
"A beautiful spacious property and very responsive property manager"
United States
Dianne D.
Open Dec 27-31/Jan 4 -9/Pool/Views/LM Deals!!

Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes

Jamul
9.4 out of 10, Exceptional, (46)
"This was an awesome place to stay. Very affordable and the host were so nice and accomodating. "
United States
Andrew K.
$488 nightly
The price is $535
Dec 10 - Dec 11
Total with taxes and fees
Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes

Coastal Contemporary Charm...Steps to the Sand!

Mission Beach
9.4 out of 10, Exceptional, (111)
"Nice stay near the beach. "
United States
Robert R.
Coastal Contemporary Charm...Steps to the Sand!

Spanish Casita in the Village of La Jolla - Walk to Everything

Village of La Jolla
9.6 out of 10, Exceptional, (270)
"We had the pleasure of meeting Yvonne after one of our walks into town. Great location to get to the La Jolla cove and great restaurants...a list of which was provided by Yvonne and Eric. We enjoyed our escape for the heat in the central valley!"
United States
Pat C.
Spanish Casita in the Village of La Jolla - Walk to Everything

Luxury Gated Mission Bay Estate with Resort Style Pool!

Bay Park
9.4 out of 10, Exceptional, (249)
"Agree with previous reviews. Great location, great view, accommodating for a large group. "
United States
David P.
Luxury Gated Mission Bay Estate with Resort Style Pool!

On the Sand! | Single-Family Oceanfront Home | AC + Sunset Views

Mission Beach
10.0 out of 10, Exceptional, (24)
"Wonderful home and host. I will be staying here again in the future! "
United States
Jose R.
On the Sand! | Single-Family Oceanfront Home | AC + Sunset Views

Ocean Breeze Heaven Pool House in La Jolla

Muirlands West
10.0 out of 10, Exceptional, (30)
"Fantastic location, very clean, perfect for family vacation in San Diego. The pool is great and neighborhood is very quiet to relax after long day of sightseeing. "
United States
Nick Y.
$801 nightly
The price is $891
Dec 8 - Dec 9
Total with taxes and fees
Ocean Breeze Heaven Pool House in La Jolla

Casa Del Cerro

Del Cerro
9.4 out of 10, Exceptional, (20)
"Family friendly - pet friendly - great location - fun for the entire family - great use of space!"
United States
Anita H.
$979 nightly
The price is $1,089
Dec 7 - Dec 8
Total with taxes and fees
Casa Del Cerro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South San Diego Hotel Reviews

Find out more about South San Diego

Everything you need to know about South San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

South San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in South San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit South San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $113 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on South San Diego rentals

At Expedia, we put the best South San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top South San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.