$622 Cheap Flights from Key West (EYW) to Istanbul (IST)

View $622 flight on Sat, Nov 8, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Istanbul Airport (IST)

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Cheap Flights from Key West to Istanbul (EYW-IST)

Prices were available within the past 7 days and start at $622 for one-way flights and $670 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Wed, Nov 19 - Wed, Dec 3
EYW
Key West
IST
Istanbul
$670 Roundtrip, found 2 days ago
$670
Roundtrip
found 2 days ago
Select British Airways flight, departing Wed, Nov 19 from Key West to Istanbul, returning Wed, Dec 3, priced at $670 found 2 days ago
British Airways
Mon, Nov 24 - Wed, Dec 3
EYW
Key West
IST
Istanbul
$675 Roundtrip, found 2 days ago
$675
Roundtrip
found 2 days ago
Select British Airways flight, departing Mon, Nov 24 from Key West to Istanbul, returning Wed, Dec 3, priced at $675 found 2 days ago
British Airways
Sat, Nov 8 - Sat, Nov 15
EYW
Key West
IST
Istanbul
$695 Roundtrip, found 4 hours ago
$695
Roundtrip
found 4 hours ago
Select British Airways flight, departing Sat, Nov 8 from Key West to Istanbul, returning Sat, Nov 15, priced at $695 found 4 hours ago
British Airways
Sat, Nov 8 - Sat, Nov 15
EYW
Key West
IST
Istanbul
$701 Roundtrip, found 4 hours ago
$701
Roundtrip
found 4 hours ago
Select British Airways flight, departing Sat, Nov 8 from Key West to Istanbul, returning Sat, Nov 15, priced at $701 found 4 hours ago
British Airways
Sat, Oct 25 - Tue, Nov 4
EYW
Key West
IST
Istanbul
$720 Roundtrip, found 4 days ago
$720
Roundtrip
found 4 days ago
Select British Airways flight, departing Sat, Oct 25 from Key West to Istanbul, returning Tue, Nov 4, priced at $720 found 4 days ago
British Airways
Sat, Nov 8 - Sat, Nov 15
EYW
Key West
IST
Istanbul
$740 Roundtrip, found 4 hours ago
$740
Roundtrip
found 4 hours ago
Select British Airways flight, departing Sat, Nov 8 from Key West to Istanbul, returning Sat, Nov 15, priced at $740 found 4 hours ago
KLM
Tue, Nov 25 - Mon, Dec 1
EYW
Key West
IST
Istanbul
$743 Roundtrip, found 2 days ago
$743
Roundtrip
found 2 days ago
Select KLM flight, departing Tue, Nov 25 from Key West to Istanbul, returning Mon, Dec 1, priced at $743 found 2 days ago
Air France
Thu, Nov 20 - Wed, Dec 3
EYW
Key West
IST
Istanbul
$763 Roundtrip, found 2 days ago
$763
Roundtrip
found 2 days ago
Select Air France flight, departing Thu, Nov 20 from Key West to Istanbul, returning Wed, Dec 3, priced at $763 found 2 days ago
Delta
Wed, Nov 19 - Mon, Dec 1
EYW
Key West
IST
Istanbul
$769 Roundtrip, found 2 days ago
$769
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Nov 19 from Key West to Istanbul, returning Mon, Dec 1, priced at $769 found 2 days ago
American Airlines
Sat, Nov 22 - Sun, Nov 30
EYW
Key West
IST
Istanbul
$1,185 Roundtrip, found 2 days ago
$1,185
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 22 from Key West to Istanbul, returning Sun, Nov 30, priced at $1,185 found 2 days ago

Alternative airports near Istanbul

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Istanbul Airport IST. Cheapest option available. Average driving time to city center is 35 minutes. Flights from $995
IST
Istanbul Airport
Cheapest
Average driving time to city center35 min
Flights from $995
Flights from Key West (EYW) to Istanbul (IST)
Origin airport
Key West Intl.
Destination airport
Istanbul
Airlines serving
Air France, British Airways, Delta, JetBlue Airways, KLM, Qatar Airways, United
Roundtrip price
$669
Distance
6081 mi

Key West to Istanbul Flights

The cheapest times to fly from Key West to Istanbul

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Istanbul are during the month of November. You can find some of the cheapest flights from Key West to Istanbul with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Istanbul

Sunday is one of the best days to book for cheap flights from Key West to Istanbul: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Istanbul

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Istanbul in 2025. You can also book with separate airlines for your outbound and return journeys, from $622 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Istanbul flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Istanbul airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Istanbul (IST) cost?
Discover the latest flight deals from EYW to IST by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from EYW to IST?
The cheapest flights from EYW to IST are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from EYW to IST?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from EYW to IST. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Key West Intl. Airport (EYW) to Istanbul (IST)?
You'll have to catch a flight with a layover when traveling from Key West Intl. Airport (EYW) to Istanbul (IST). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from EYW to IST?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Istanbul (IST)?
Choose a flight from Key West Intl. Airport (EYW) to Istanbul (IST) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Istanbul (IST) last-minute?
Last-minute fares from EYW to IST are usually more expensive. To lock in the cheapest rates, start looking for flights ahead of time. That said, if your travel plans are flexible, you may score a cheap ticket right before you leave.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Istanbul (IST)?
You can usually cancel or reschedule your EYW to IST flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.