Find 3 Star Hotels in O Brien, FL from $103
- Upfront pricingOur total price for your stay includes taxes and fees
- Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
- Be pickySearch almost a million properties worldwide
Check availability on O Brien 3 Star Hotels
Compare O Brien 3 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn & Suites Lake City by IHG

Courtyard By Marriott Lake City

Home2 Suites by Hilton Lake City

TownePlace Suites by Marriott Lake City

Lake Butler Cabin on 5 Acres w/ Fire Pit!

Rustic Lake City Studio Near Ichetucknee Springs!

Serene Live Oak Home w/ Fire Pit by River + Sosmp!
Learn more about O Brien
Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

Top O Brien Hotel Reviews

Holiday Inn & Suites Lake City by IHG

Courtyard By Marriott Lake City
Find out more about O Brien
Three Star Hotel Guide for O Brien
There’s a reason the top 3 star hotels in O Brien, Florida are so incredibly popular: They combine comforting amenities and just-for-you service with some of the best rates and discounts the area has to offer. When you book a stay at a three star hotel in O Brien, you’ll get access to perfect little perks like on-site restaurants and cocktail bars, well-appointed fitness centers, and spacious rooms.
Search for a cheap deal on a 3 star upscale hotel in O Brien for the most elegant experience, or grab a low rate on one of the cheap 3 star hotels in O Brien near the local attractions, if you want something a touch more unassuming. Whatever your traveling style, make sure to use the search tools at Expedia to track down prices, read more about amenities, and score a few local discounts.
From business trips to family getaways, the O Brien 3 star hotels offer a fantastic home base for any type of vacation.
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Troy Spring State Park
- 4 Star Hotels in Branford
- 5 Star Hotels in Branford
- 3 Star Hotels in Branford
- Branford Hotels
- Motels in Branford
- Cabin Rentals in Branford
- RV Parks in Branford
- Apartments in Branford
- Vacation Homes in Branford
- Cottages in Branford
- 5 Star Hotels in Mcalpin
- Mcalpin Hotels
- Cabin Rentals in Mcalpin
- RV Parks in Mcalpin
- Motels in Mcalpin
- Cottages in Mcalpin
- Apartments in Mcalpin
- Hotels near Ichetucknee River
- Hotels near Ichetucknee Springs State Park
- Alton Hotels
- Hotels near Wes Skiles Peacock Springs State Park
- Mayo Hotels
- Cabin Rentals in Mayo
- Cottages in Mayo
- Motels in Mayo
- Apartments in Mayo
- Vacation Homes in Mayo
- 4 Star Hotels in Wellborn
- 5 Star Hotels in Wellborn
- Wellborn Hotels
- Cabin Rentals in Wellborn
- Motels in Wellborn
- RV Parks in Wellborn
- 5 Star Hotels in Fort White
- 3 Star Hotels in Fort White
- Fort White Hotels
- Cabin Rentals in Fort White
- Hotels with a View in Fort White
- Condo Rentals in Fort White
- Vacation Homes in Fort White
- La Quinta Inn & Suites Hotels in Fort White
- Romantic Hotels in Fort White
- Marriott Hotels & Resorts in Fort White
- Hotels with Restaurants in Fort White
- Pet-friendly Hotels in Fort White
- Historic Hotels in Fort White
- Motels in Fort White
- Hotels near Bob's River Place
- Hotels near Baker Park
- Hotels near First Federal Sportsplex
- 5 Star Hotels in Live Oak
- 3 Star Hotels in Live Oak
- Live Oak Hotels
- Pet-friendly Hotels in Live Oak
- Cabin Rentals in Live Oak
- Cheap Hotels in Live Oak
- Motels in Live Oak
- Condo Rentals in Live Oak
- Car rentals near Branford
- Car rentals near Mcalpin
- Car rentals near Ichetucknee Springs State Park
- Car rentals near Alton
- Car rentals near Wes Skiles Peacock Springs State Park
- Car rentals near Mayo
- Car rentals near Wellborn
- Car rentals near Fort White
- Car rentals near Bob's River Place
- Car rentals near Live Oak
- Enterprise Rental Cars in Live Oak
- Budget Rental Cars in Live Oak








































































