Find 5 Star Hotels in Cow Key, FL from $183
Most hotels are fully refundable. Because flexibility matters.
Save 10% or more on over 100,000 hotels worldwide as a One Key member.
Search over 2.9 million properties and 550 airlines worldwide.
Check availability on Cow Key 5 Star Hotels
Compare Cow Key 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Casa Marina Key West, Curio Collection by Hilton
Explore similar 4-star hotels
La Concha Key West
Indulge your every whim on your next sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Cow Key so popular in the last year. There's no reason to delay a getaway to Cow Key any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Cow Key and get ready to be pampered like never before. Don't wait any longer!
5-Star Hotels in Cow Key
You'll have a wonderful time at one of these 5-star hotels. Top-notch service, delicious meals, and attentive guest service are all ready for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? Fluffy down pillows, delectable chocolate desserts, and even spectacular views...these hotels are one-of-a-kind. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
Yearning for experiences outside your hotel room? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Cow Key are waiting for you to rest up after an exciting day.
Your Getaway Starts Today
The results are in, and Cow Key 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Opt for one of our Cow Key 5-star hotels today and soothe yourself in total tranquility at your convenience.
Frequently asked questions
Cow Key Hotels by Star Rating
Stay near popular Cow Key attractions
- Duval Street
- Mallory Square
- Smathers Beach
- Southernmost Point
- South Beach
- Ernest Hemingway Home and Museum
- Key West Golf Club
- Fort Zachary Taylor Historic State Park
- Clarence S. Higgs Memorial Beach Park
- Stock Island Yacht Club & Marina
- Boca Chica Nude Beach
- Harry S. Truman Little White House
- Key West Butterfly and Nature Conservatory
- Key West Lighthouse and Keeper's Quarters Museum
- Florida Keys National Marine Sanctuary
- Mel Fisher Maritime Museum
- Audubon House and Tropical Gardens
- Key West Shipwreck Museum
- Key West Tropical Forest and Botanical Garden
- Simonton Beach
More Accommodation Types in Cow Key
- Vacation Homes in Cow Key (760)
- Condo Rentals in Cow Key (476)
- Apartments in Cow Key (183)
- Cottages in Cow Key (123)
- Houseboats in Cow Key (37)
- Resorts in Cow Key (35)
- Villas in Cow Key (30)
- Guest Houses in Cow Key (26)
- B&B in Cow Key (21)
- RV Parks in Cow Key (6)
- Cabin Rentals in Cow Key (5)
- Aparthotels in Cow Key (3)
- Condo Resorts in Cow Key (1)
- Hostels in Cow Key (1)
Explore more hotels
- Winslow's Bungalows - Key West Historic Inns
- DoubleTree Resort by Hilton Grand Key - Key West
- Parrot Key Hotel & Villas
- Fairfield Inn and Suites by Marriott Key West
- The Gates Hotel Key West
- The Laureate Key West
- NYAH Key West - Adults Only
- Heron House - Adult Only
- The Reach Key West, Curio Collection by Hilton
- Heron House Court - Adult Only
- Opal Key Resort & Marina, Key West
- Southwinds Motel
- Hampton Inn Key West FL
- Casa Marina Key West, Curio Collection by Hilton
- Pier House Resort & Spa
- Hyatt Vacation Club at Windward Pointe, Key West
- The Southernmost Inn - Adults Only
- Seashell Motel & Key West Hostel
- Eden House
- The Marker Key West Harbor Resort