Find 5 Star Hotels in Karlín from $87

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Compare Karlín 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Michelangelo Grand Hotel Prague

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (3104)
"Great location, lovely hotel "
United Kingdom
Sally Louise
$124 nightly
The price is $144
Jan 7 - Jan 8, 2026
Total with taxes and fees
Michelangelo Grand Hotel Prague

Almanac X Alcron Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (824)
"Fab room, fab, friendly staff, excellent location! Highly recommended!!"
United Kingdom
Kevin
$168 nightly
The price is $193
Jan 7 - Jan 8, 2026
Total with taxes and fees
Almanac X Alcron Prague

Hilton Prague

5.0 star property
Karlín
8.4 out of 10, Very Good, (1004)
"Very excellent Hotel would recommend to anyone!"
Canada
Damien
$76 nightly
The price is $90
Jan 7 - Jan 8, 2026
Total with taxes and fees
Hilton Prague

Grandior Hotel Prague

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1203)
"Fabulous place to stay and within easy walking distance to shops and places of interest. "
United Kingdom
Mairi
$99 nightly
The price is $115
Jan 6 - Jan 7, 2026
Total with taxes and fees
Grandior Hotel Prague

Grandium Hotel Prague

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1120)
"Great rooms, friendly staff, wonderful breakfast"
United States
Toni
$114 nightly
The price is $133
Jan 6 - Jan 7, 2026
Total with taxes and fees
Grandium Hotel Prague

Four Seasons Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (612)
"All perfect"
United States
Amos
$675 nightly
The price is $761
Jan 4 - Jan 5, 2026
Total with taxes and fees
Four Seasons Hotel Prague

ANDAZ PRAGUE, BY HYATT

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (172)
"Overall a great experience."
United Kingdom
Mark
$272 nightly
The price is $310
Jan 5 - Jan 6, 2026
Total with taxes and fees
ANDAZ PRAGUE, BY HYATT

Radisson Blu Hotel, Prague

5.0 star property
Nové Město
9.2 out of 10, Wonderful, (499)
"Excellent services, well trained staff."
United States
TETIANA
$126 nightly
The price is $146
Jan 7 - Jan 8, 2026
Total with taxes and fees
Radisson Blu Hotel, Prague

Iron Gate Hotel & Suites Prague by BHG

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1007)
"Nice rooms, good staff"
Canada
Prasanna K.
$130 nightly
The price is $150
Jan 6 - Jan 7, 2026
Total with taxes and fees
Iron Gate Hotel & Suites Prague by BHG

Kosher Hotel KING DAVID Prague

5.0 star property
Prague City Center
8.2 out of 10, Very Good, (918)
"Lovely spacious rooms, great food. "
United States
Adena
$169 nightly
The price is $194
Dec 14 - Dec 15
Total with taxes and fees
Kosher Hotel KING DAVID Prague

Grand Hotel Bohemia

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1003)
"Beautiful hotel in an excellent location for exploring the historic centre of Prague. We enjoyed a comfortable room, the hotel bar and would highly recommend the amazing breakfast."
United Kingdom
Janette Elizabeth
$159 nightly
The price is $183
Jan 5 - Jan 6, 2026
Total with taxes and fees
Grand Hotel Bohemia

Falkensteiner Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (420)
"Great hotel near main rail station"
United States
Alexander
$150 nightly
The price is $173
Jan 6 - Jan 7, 2026
Total with taxes and fees
Falkensteiner Hotel Prague

Prague Marriott Hotel

5.0 star property
Prague City Center
9.0 out of 10, Wonderful, (1000)
"Wonderful hotel, great location, everything was perfect."
United States
Michael
$204 nightly
The price is $233
Jan 7 - Jan 8, 2026
Total with taxes and fees
Prague Marriott Hotel

Cosmopolitan Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1070)
"Great location and fantastic hotel "
United Kingdom
David
$145 nightly
The price is $167
Jan 7 - Jan 8, 2026
Total with taxes and fees
Cosmopolitan Hotel Prague

Hotel Kings Court

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1006)
"The hotel was amazing! We loved our upgraded rooms and enjoyed the spa. The food was also amazing! "
United States
Melissa Ann
$155 nightly
The price is $179
Jan 7 - Jan 8, 2026
Total with taxes and fees
Hotel Kings Court

The Grand Mark Prague - The Leading Hotels of the World

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (734)
"Perfect location Nice, clean hotel Friendly staff "
United States
inna
$283 nightly
The price is $318
Jan 5 - Jan 6, 2026
Total with taxes and fees
The Grand Mark Prague - The Leading Hotels of the World

Hilton Prague Old Town

5.0 star property
Prague City Center
8.8 out of 10, Excellent, (1001)
"Lovely hotel"
United Kingdom
ira
$168 nightly
The price is $193
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hilton Prague Old Town

The Mozart Prague by Accor

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1005)
"Amazing stay!!!"
United Kingdom
Aimee
$248 nightly
The price is $282
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Mozart Prague by Accor

Eurostars Thalia

5.0 star property
Prague City Center
8.8 out of 10, Excellent, (713)
"Clean room, friendly stuff, good food on breakfast."
United States
Leonid
$74 nightly
The price is $87
Jan 7 - Jan 8, 2026
Total with taxes and fees
Eurostars Thalia

Art Deco Imperial Hotel

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1000)
"Room was spotless and the premises are amazing. "
United States
Susan
$154 nightly
The price is $178
Jan 5 - Jan 6, 2026
Total with taxes and fees
Art Deco Imperial Hotel
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Frequently asked questions

What are the best 5-star hotels in Karlín?
A world of luxury awaits at Hilton Prague, Urban Creme and Grandior Hotel Prague. These are among the 5-star escapes around the Prague neighborhood of Karlín that rate highly with Expedia guests.
How much does it cost to stay in a 5-star hotel in Karlín?
How much you pay for a 5-star hotel in Karlín can vary according to when you decide to travel and how long you plan to be away, among several factors. Take advantage of our price per night filter and other search tools to score the best rate on an indulgent stay.

  • Search for the lowest price per night from $110

What makes a hotel 5 stars in Karlín?
In Karlín, a hotel must offer a certain number of upscale amenities to be designated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You'll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer additional touches such as a welcome gift.

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