Top 10 Hotels in Drew, MS (from $53) 2026 - Competitive Prices

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Our top choices for Drew hotels

A modern restaurant with brick walls, multiple seating areas, and pendant lighting.

A modern kitchen with a black marble island, a brick wall, and a large window.

A modern hotel lobby with a dining area, sofas, and a large window offering a view.

A large, multi-story building with a symmetrical facade, multiple balconies, and a well-lit entrance.

1. Lyric Hotel West End, Trademark Collection by Wyndham

Cleveland

Heather

$126 nightly

$138 total

Oct 4 - Oct 5

Total with taxes and fees

A spacious living area with a wooden floor, a sofa, a coffee table, and a dining area visible through a glass door.

A spacious room with large windows, a polished concrete floor, and multiple circular chandeliers.

A spacious living area with a large fireplace, two sofas with side tables, and a coffee table.

A modern living room with a fireplace, wooden beams, and a large abstract painting.

2. Cotton House, Cleveland, a Tribute Portfolio Hotel

Cleveland

Carla

$139 nightly

$152 total

Sep 20 - Sep 21

Total with taxes and fees

A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

A bathroom with a white countertop, a sink, a mirror, and a towel rack.

A reception area with a large number '6' on the wall, a reception desk, a computer, and a painting on the wall.

A Wendy's restaurant with a 6 Motel sign nearby.

3. Motel 6 Cleveland, MS - Delta State University

Cleveland

John

$73 nightly

$80 total

Sep 7 - Sep 8

Total with taxes and fees

An indoor swimming pool with a brick column, a staircase, and a balcony with chairs.

A hotel breakfast area with a granite counter, a coffee machine, a fruit bowl, and a clock on the wall.

A modern interior with a vending machine, refrigerated display, and a window view.

A hotel room with a large bed, a desk, a chair, a wheelchair, and a mirror.

4. SureStay Plus Hotel by Best Western Greenwood

Greenwood

Horace

$127 nightly

$137 total

Sep 20 - Sep 21

Total with taxes and fees

A modern hotel room with a bed, a desk, and a chair.

A modern kitchen with a dining area, featuring a large window, a refrigerator, and a coffee station.

A compact room with a flat-screen TV mounted on the wall, a small kitchenette with a microwave, and a blue chair.

5. Motel 6 Greenwood, MS

Greenwood

John

$73 nightly

$79 total

Sep 16 - Sep 17

Total with taxes and fees

A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.

A Hampton Inn with a modern beige facade, a flag, and a covered entrance.

A rectangular swimming pool with a blue interior, surrounded by a brick border and a metal railing.

A hotel room with a large bed, a bedside table with a lamp, a chair, a bench, and a patterned carpet.

6. Hampton Inn Clarksdale

Clarksdale

Judy

$131 nightly

$143 total

Sep 20 - Sep 21

Total with taxes and fees

A buffet with labeled sections for omelets and cheese.

A hotel room with a dining table, four chairs, a sofa, a TV, and a large window with curtains.

A hotel lobby with a brown leather sofa, two striped pillows, a floor lamp, and two floral paintings on the wall.

A fitness room with a treadmill, elliptical, and weight machines.

7. Holiday Inn Express Hotel & Suites Cleveland by IHG

Cleveland

Linda

$103 nightly

$112 total

Oct 5 - Oct 6

Total with taxes and fees

A lobby with seating, a reception desk, a plant, and a painting on the wall.

A hotel room with a bed, bedside tables, a desk, and a chair.

A self-service beverage station with various drink dispensers and a refrigerator.

A hotel room with a bed, a sofa, a small table, and a window with curtains.

8. Quality Inn Clarksdale

Clarksdale

Blu

$84 nightly

$92 total

Sep 29 - Sep 30

Total with taxes and fees

A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.

A spacious lobby with a green door, a beige sofa, a wooden coffee table, and a large window offering a view of the outside.

A dining area with a table and four chairs, a potted plant, and a lamp.

A cozy room with a fireplace, a bar area with bottles and glasses, and a view of the street outside.

9. Travelers Hotel

Clarksdale

Carl

$150 nightly

$164 total

Oct 7 - Oct 8

Total with taxes and fees

A coffee station with two coffee machines and a variety of coffee pods and cups.

A living room with striped furniture, a lamp, and a painting on the wall.

A hotel room with a bed, a desk, a chair, a sofa, and a lamp.

10. Holiday Inn Express & Suites - Greenwood by IHG

Greenwood

Jaime

$183 nightly

$198 total

Sep 9 - Sep 10

Total with taxes and fees

A Super 8 hotel with a large sign, covered parking, and well-maintained landscaping.

A breakfast area with a coffee machine, microwave, and seating.

A hotel lobby with a reception desk, a coffee machine, and a mirror on the wall.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

11. Super 8 by Wyndham Indianola

Indianola

Mary

$90 nightly

$98 total

Sep 20 - Sep 21

Total with taxes and fees

A modern living room with a brick wall, a flat-screen TV, and a fireplace. There are two blue sofas with red cushions, a glass coffee table, and a small wooden side table.

A sign for Delta State University with a brick base and green lettering, surrounded by a well-maintained lawn and flowering plants.

A hotel room with a bed, two bedside lamps, a desk with a chair, a mirror, and a patterned carpet.

A hotel reception desk with a digital screen, a clock, and a sign that reads "Quality by Choice Hotels".

12. Quality Inn Indianola

Indianola

Wendy

$69 nightly

$75 total

Oct 4 - Oct 5

Total with taxes and fees

A modern living room with two grey sofas, a coffee table, and a decorative wall unit with a vase.

A gym with treadmills and stationary bikes, a clock on the wall, and a trash can.

A reception desk with framed pictures, a "Welcome to Greenwood" sign, a "Manager On Duty" sign, and a lamp.

A coffee station with multiple coffee dispensers, a trash can, and a small shelf with snacks.

13. Hampton Inn Greenwood

Greenwood

Alexis

$144 nightly

$155 total

Oct 4 - Oct 5

Total with taxes and fees

A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.

A hotel reception area with a reception desk, a framed picture, a door with a keypad, and a blue mat at the entrance.

A hotel room with two beds, a desk with a computer, a chair, a television, and two lamps.

A compact black refrigerator with a microwave on top, a small wooden table, and a potted plant.

14. Americas Best Value Inn & Suites Clarksdale

Clarksdale

Kartreace

$78 nightly

$86 total

Oct 5 - Oct 6

Total with taxes and fees

A bedroom with a bed, a nightstand, a dresser, a microwave, and a bathroom visible through an open door.

A bathroom with a white sink, mirror, and a view of a kitchen in the background.

A parking lot with several cars and a building with a brick facade and a metal roof.

15. Ruleville Inn By OYO

Ruleville

Tracy

$51 nightly

$54 total

Sep 7 - Sep 8

Total with taxes and fees

A commercial building with a parking lot, a sign for 'Americas Best Value Inn by Sonesta', and a satellite dish on the roof.

A room with a kitchen, dining area, and seating space.

A compact kitchen with wooden cabinets, a countertop, and a dining area with a wooden table and chairs.

16. Americas Best Value Inn Indianola

Indianola

laqunta

$73 nightly

$80 total

Sep 7 - Sep 8

Total with taxes and fees

A sign for the Deluxe Inn & Suites with a building in the background.

A two-story building with a blue roof, a parking lot with several cars, and a grassy area with trees.

A hotel room with a wooden desk, a flat-screen TV, a microwave, and a refrigerator.

A hotel room with a bed, desk, chair, and ottoman.

17. Rodeway Inn

Greenwood

Eric

$68 nightly

$73 total

Sep 27 - Sep 28

Total with taxes and fees

A hotel room with a bed, a dresser, a television, and a small refrigerator.

A motel with a red exterior, a covered parking area, and a small outdoor seating area.

A bathroom with a bathtub, toilet, and shower curtain.

A hotel room with two beds, a desk, a mirror, and a window with curtains.

18. c towninn and suites

Cleveland

Jumeal

$49 nightly

$53 total

Sep 17 - Sep 18

Total with taxes and fees

A hotel room with two beds, a headboard, bedside lamps, and a patterned carpet.

A kitchen area with a waffle maker, syrup dispenser, coffee machine, and a sign indicating breakfast hours.

A living room with two grey sofas, a coffee table with magazines and fruit, and a TV on a stand.

A reception area with a counter, a clock, a computer, and a dining area with chairs and a table.

19. Americas Best Value Inn & Suites Greenwood

Greenwood

Betty

$80 nightly

$87 total

Oct 2 - Oct 3

Total with taxes and fees

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Top Drew Hotel Reviews

Lyric Hotel West End, Trademark Collection by Wyndham

10/10 Excellent

"Staff is always great! Very attentive. Nice. Professional."

Hampton Inn Clarksdale

10/10 Excellent

"The breakfast was amazing, the best we have ever had as a hotel breakfast. The lady keep refreshing items and cleaning area very good"

Cotton House, Cleveland, a Tribute Portfolio Hotel

8/10 Good

"I enjoyed my stay the room was clean and the bar and restaurant food was great"

Holiday Inn Express Hotel & Suites Cleveland by IHG

8/10 Good

"The staff were friendly and kind. We checked in before a major storm which caused the roof to leak over our bed. I called the front desk and was moved immediately. Also they are renovating the hotel so it makes the hotel look rundown. Once they finish I’m sure that will all change. Overall a good experience."

Honnoll's High Cotton Guesthouse

10/10 Excellent

"We needed last minute accommodations to attend a funeral and we were traveling with dogs. The owner was very accommodating and responsive and the guesthouse suited our needs perfectly. I would definitely recommend this."

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

10/10 Excellent

"There was a total of 15 of us, Siblings with our children. We had a great time with thoroughly enjoyed the pool and all the laughter just hanging out playing games and eating meals together. A great place for a lot of people."

Auberge Clarksdale Blues Hostel

10/10 Excellent

"My first time in a hostel and was sort of dreading it, but it was lovely. Shared bathroom was more like a locker room. Great location to walk everywhere."

Sunset Log Cabin

10/10 Excellent

"Clean and comfortable accommodation. Great location. reasonable price. I'll be back!"

Quality Inn Cleveland, MS

10/10 Excellent

"Pretty good breakfast! Nice staff.."

More cheap stays in Drew

Motel 6 Cleveland, MS - Delta State University

721 N Davis Ave Cleveland MS

$73 nightly

$80 total

Sep 7 - Sep 8

Total with taxes and fees

8.2/10 Very Good! (323 reviews)

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS

$78 nightly

$86 total

Oct 5 - Oct 6

Total with taxes and fees

6/10 (430 reviews)

Quality Inn Clarksdale

818 South State Street Clarksdale MS

$84 nightly

$92 total

Sep 29 - Sep 30

Total with taxes and fees

Holiday Inn Express Hotel & Suites Cleveland by IHG

808 N Davis Ave Cleveland MS

$103 nightly

$112 total

Oct 5 - Oct 6

Total with taxes and fees

7.8/10 Good! (993 reviews)

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS

$131 nightly

$143 total

Sep 20 - Sep 21

Total with taxes and fees

8.2/10 Very Good! (403 reviews)

Travelers Hotel

212 3rd St Clarksdale MS

$150 nightly

$164 total

Oct 7 - Oct 8

Total with taxes and fees

Hotels in Drew with star-rating

Frequently asked questions

What is the best area to stay in Drew?

The best area to stay in Drew, Mississippi, is near the town center, particularly along South Main Street.This central area offers convenient access to local establishments. It features a few blocks of businesses and residences, giving you a sense of local life. You'll find the town's primary amenities concentrated here, making it easy to navigate on foot.For travelers seeking a quiet and authentic experience, staying near the town center is ideal. It provides a direct connection to the community, allowing you to easily visit local eateries or shops.

When is the best time to go to Drew?

The best time to visit Drew, Mississippi, is during the spring (late March to May) and fall (September to October) months.These seasons offer pleasant weather with mild temperatures and lower humidity, making it comfortable for exploring the area. Springtime brings blooming flora, while the fall delivers crisp air and colorful foliage, enhancing the scenic beauty of the Mississippi Delta.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Drew.

How much is the nightly rate at a Drew hotel?

Prices for hotels in Drew often vary, but you can find a great deal from $53 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Things to do in Mississippi Delta

Find hotels in Drew, MS from $53

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Drew

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Drew hotels

1. Lyric Hotel West End, Trademark Collection by Wyndham

2. Cotton House, Cleveland, a Tribute Portfolio Hotel

3. Motel 6 Cleveland, MS - Delta State University

4. SureStay Plus Hotel by Best Western Greenwood

5. Motel 6 Greenwood, MS

6. Hampton Inn Clarksdale

7. Holiday Inn Express Hotel & Suites Cleveland by IHG

8. Quality Inn Clarksdale

9. Travelers Hotel

10. Holiday Inn Express & Suites - Greenwood by IHG

11. Super 8 by Wyndham Indianola

12. Quality Inn Indianola

13. Hampton Inn Greenwood

14. Americas Best Value Inn & Suites Clarksdale

15. Ruleville Inn By OYO

16. Americas Best Value Inn Indianola

17. Rodeway Inn

18. c towninn and suites

19. Americas Best Value Inn & Suites Greenwood

Top Drew Hotel Reviews

Lyric Hotel West End, Trademark Collection by Wyndham

Hampton Inn Clarksdale

Cotton House, Cleveland, a Tribute Portfolio Hotel

Holiday Inn Express Hotel & Suites Cleveland by IHG

Honnoll's High Cotton Guesthouse

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

Auberge Clarksdale Blues Hostel

Sunset Log Cabin

Quality Inn Cleveland, MS

More cheap stays in Drew

Motel 6 Cleveland, MS - Delta State University

Americas Best Value Inn & Suites Clarksdale

Quality Inn Clarksdale

Holiday Inn Express Hotel & Suites Cleveland by IHG

Hampton Inn Clarksdale

Travelers Hotel

Hotels in Drew with star-rating

Frequently asked questions

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