Top 10 Hotels in Drew, MS (from $50) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Drew

Pet friendly

Apartment

Condo

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Drew hotels

A spacious restaurant with high ceilings, wooden beams, and modern lighting fixtures.

A modern kitchen with a black marble island, a brick wall, and a large window.

A modern hotel lobby with a dining area, sofas, and a large window offering a view.

A spacious living room with a fireplace, modern furniture, and a chandelier.

1. Lyric Hotel West End, Trademark Collection by Wyndham

Cleveland

Britiani

$125 nightly

$136 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious living area with a wooden floor, a sofa, a coffee table, and a dining area visible through a glass door.

A multi-story building with a sign reading "Cotton House."

A modern living room with a fireplace, wooden beams, and a large abstract painting.

A spacious living area with a large fireplace, two sofas with side tables, and a coffee table.

2. Cotton House, Cleveland, a Tribute Portfolio Hotel

Cleveland

John

$139 nightly

$152 total

Nov 8 - Nov 9

Total with taxes and fees

A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

A Wendy's restaurant with a 6 Motel sign nearby.

A motel with a covered parking area and a gas station in the background.

A reception area with a large number '6' on the wall, a reception desk, a computer, and a painting on the wall.

3. Motel 6 Cleveland, MS - Delta State University

Cleveland

Richelle

$73 nightly

$80 total

Oct 25 - Oct 26

Total with taxes and fees

An indoor swimming pool with a brick column, a staircase, and a balcony with chairs.

A modern interior with a vending machine, refrigerated display, and a window view.

A hotel breakfast area with a granite counter, a coffee machine, a fruit bowl, and a clock on the wall.

A hotel room with a large bed, a desk, a chair, a wheelchair, and a mirror.

4. SureStay Plus Hotel by Best Western Greenwood

Greenwood

Chidinma

$127 nightly

$137 total

Nov 1 - Nov 2

Total with taxes and fees

A modern hotel room with a bed, a desk, and a chair.

A compact room with a flat-screen TV mounted on the wall, a small kitchenette with a microwave, and a blue chair.

A vending machine and an ice dispenser in a hallway.

5. Motel 6 Greenwood, MS

Greenwood

Alan

$74 nightly

$80 total

Oct 23 - Oct 24

Total with taxes and fees

A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.

A Hampton Inn with a modern beige facade, a flag, and a covered entrance.

A hotel room with a large bed, a bedside table with a lamp, a chair, a bench, and a patterned carpet.

A reception desk with a wooden finish, a framed welcome sign, and a lamp.

6. Hampton Inn Clarksdale

Clarksdale

Judy

$130 nightly

$142 total

Nov 1 - Nov 2

Total with taxes and fees

A lobby with patterned carpet, two sofas, a round coffee table, a plant, and a framed picture on the wall.

A lobby with two armchairs, a round ottoman, a small table with two lamps, and a framed artwork on the wall.

A hotel room with a bed, bedside tables, a desk, and a television.

A self-service beverage station with various drink dispensers and a refrigerator.

7. Quality Inn Clarksdale

Clarksdale

Blu

$80 nightly

$87 total

Nov 12 - Nov 13

Total with taxes and fees

A hotel lobby with a reception desk, chairs, and a hallway leading to the exit.

A fitness room with a treadmill, elliptical, and weight machines.

A buffet with labeled sections for omelets and cheese.

A hotel lobby with a brown leather sofa, two striped pillows, a floor lamp, and two floral paintings on the wall.

8. Holiday Inn Express Hotel & Suites Cleveland by IHG

Cleveland

Kwanza

$113 nightly

$123 total

Nov 21 - Nov 22

Total with taxes and fees

A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.

A spacious lobby with a green door, a beige sofa, a wooden coffee table, and a large window offering a view of the outside.

A cozy room with a fireplace, a bar area with bottles and glasses, and a view of the street outside.

A window with the text "TRAVELERS HOTEL" and a reflection of a bar area with stools and a counter.

9. Travelers Hotel

Clarksdale

Suzanne

$144 nightly

$157 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a sofa, and a lamp.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel with a red and white facade, a covered entrance with columns, and a parking lot.

10. Holiday Inn Express & Suites - Greenwood by IHG

Greenwood

Gayle

$161 nightly

$174 total

Nov 1 - Nov 2

Total with taxes and fees

A modern living room with a brick wall, a flat-screen TV, and a fireplace. There are two blue sofas with red cushions, a glass coffee table, and a small wooden side table.

A hotel room with a bed, two bedside lamps, a desk with a chair, a mirror, and a patterned carpet.

A hotel reception desk with a digital screen, a clock, and a sign that reads "Quality by Choice Hotels".

A sign for Delta State University with a brick base and green lettering, surrounded by a well-maintained lawn and flowering plants.

11. Quality Inn Indianola

Indianola

LINDA

$61 nightly

$67 total

Nov 12 - Nov 13

Total with taxes and fees

A Super 8 hotel with a large sign, covered parking, and well-maintained landscaping.

A room with two patterned sofas, a wooden coffee table, and a door labeled "Great Room 3".

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A breakfast area with a coffee machine, microwave, and seating.

12. Super 8 by Wyndham Indianola

Indianola

Mary

$72 nightly

$78 total

Nov 15 - Nov 16

Total with taxes and fees

A modern living room with two grey sofas, a coffee table, and a decorative wall unit with a vase.

A reception desk with framed pictures, a "Welcome to Greenwood" sign, a "Manager On Duty" sign, and a lamp.

A hotel room with a single armchair, two bedside lamps, a bedside table with a phone, and a framed picture on the wall.

A coffee station with multiple coffee dispensers, a trash can, and a small shelf with snacks.

13. Hampton Inn Greenwood

Greenwood

Silvia

$143 nightly

$154 total

Nov 22 - Nov 23

Total with taxes and fees

A bathroom with a white sink, mirror, and a view of a kitchen in the background.

A bedroom with a bed, a nightstand, a dresser, a microwave, and a bathroom visible through an open door.

A corner of a brick building with a window and a small shelf.

14. Ruleville Inn By OYO

Ruleville

Tracy

$47 nightly

$50 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.

A compact black refrigerator with a microwave on top, a small wooden table, and a potted plant.

A hotel reception area with a reception desk, a framed picture, a door with a keypad, and a blue mat at the entrance.

A hotel room with two beds, a desk with a computer, a chair, a television, and two lamps.

15. Americas Best Value Inn & Suites Clarksdale

Clarksdale

Dave

$80 nightly

$87 total

Oct 23 - Oct 24

Total with taxes and fees

A hotel room with a bed, a dresser, a desk with a mirror, and a view of the outdoors.

A hotel room with a wooden desk, a flat-screen TV, a microwave, and a refrigerator.

A living room with a wooden ceiling, a sofa, a coffee table, a potted plant, and artwork on the walls.

A two-story building with a blue roof, a parking lot with several cars, and a grassy area with trees.

16. Rodeway Inn

Greenwood

Arth

$57 nightly

$61 total

Oct 25 - Oct 26

Total with taxes and fees

A room with a kitchen, dining area, and seating space.

A reception area with a desk, a computer, and a wooden door.

A commercial building with a parking lot, a sign for 'Americas Best Value Inn by Sonesta', and a satellite dish on the roof.

17. Americas Best Value Inn Indianola

Indianola

Nathaniel

$73 nightly

$80 total

Oct 23 - Oct 24

Total with taxes and fees

A hotel room with a bed, a dresser, a television, and a small refrigerator.

A two-story building with a red roof and a covered parking area.

A hotel room with two beds, a desk, a mirror, and a window with curtains.

A bathroom with a bathtub, toilet, and shower curtain.

18. c towninn and suites

Cleveland

Angela

$55 nightly

$60 total

Oct 23 - Oct 24

Total with taxes and fees

A hotel room with two beds, a headboard, bedside lamps, and a patterned carpet.

A living room with two grey sofas, a coffee table with magazines and fruit, and a TV on a stand.

A hotel room with a desk, a television, a refrigerator, a chair, and a lamp.

A kitchen area with a waffle maker, syrup dispenser, coffee machine, and a sign indicating breakfast hours.

19. Americas Best Value Inn & Suites Greenwood

Greenwood

Betty

$85 nightly

$92 total

Oct 23 - Oct 24

Total with taxes and fees

A log cabin interior with a stone fireplace, wooden walls, and a dining area.

A log cabin interior with a leather sofa, a coffee table, and a hanging plant.

A spacious indoor area with wooden walls and a polished concrete floor. There are several seating areas with leather sofas and armchairs. A large, colorful abstract painting adorns the wall, and a chandelier hangs from the ceiling.

A building with a large garage door, outdoor seating area with chairs and a fire pit, and a tree in the background.

20. The Delta Lodge - Greenwood, MS

Greenwood

Paul T.

$1,063 nightly

$1,137 total

Oct 25 - Oct 26

Total with taxes and fees

View all properties

Compare top hotels in Drew

Lyric Hotel West End, Trademark Collection by Wyndham Cleveland View	Cotton House, Cleveland, a Tribute Portfolio Hotel Cleveland View	Motel 6 Cleveland, MS - Delta State University Cleveland View	SureStay Plus Hotel by Best Western Greenwood Greenwood View	Motel 6 Greenwood, MS Greenwood View
8.4 Very good 328 reviews	9.0 Wonderful 717 reviews	8.2 Very good 338 reviews	8.2 Very good 782 reviews	7.8 Good 219 reviews
$125 nightly $136 total Nov 1 - Nov 2 Total with taxes and fees	$139 nightly $152 total Nov 8 - Nov 9 Total with taxes and fees	$73 nightly $80 total Oct 25 - Oct 26 Total with taxes and fees	$127 nightly $137 total Nov 1 - Nov 2 Total with taxes and fees	$74 nightly $80 total Oct 23 - Oct 24 Total with taxes and fees

Save an average of 15% on thousands of hotels when you're signed in

Top Drew Hotel Reviews

Auberge Clarksdale Blues Hostel

10/10 Excellent

"We've stayed here a few times and it's always comfortable and clean. Highly recommend for an inexpensive stay"

Holiday Inn Express Hotel & Suites Cleveland by IHG

10/10 Excellent

"The property is clean and well maintained even though it is under renovation. It was still clean and the staff is phenomenal. They are very attentive and welcoming. Breakfast and the coffee are so good! My stay was great and I will be returning!"

Motel 6 Cleveland, MS - Delta State University

10/10 Excellent

"Friendly and helpful."

Hampton Inn Clarksdale

8/10 Good

"staff was friendly. Food was hot. No bugs. bed was clean"

Travelers Hotel

10/10 Excellent

"Friendly, helpful staff and set in a great location. Loved the shared kitchen and all its amenities. Would definitely stay here again."

The Sunflower Penthouse on the River in Clarksdale

8/10 Good

"Great place to stay."

Only a mile from historic downtown Clarksdale!

10/10 Excellent

"Nice & quiet place to stay. Perfect for our anniversary weekend."

Sunset Log Cabin

10/10 Excellent

"Libby is a very professional and responsive host. The place was perfect for my needs, allowed my dog, easy to get to town, yet also a bit on outskirts so not surrounded by hustle and bustle. Pleasant, rustic vibe, relaxing, and would definitely stay again."

Honnoll's High Cotton Guesthouse

10/10 Excellent

"We needed last minute accommodations to attend a funeral and we were traveling with dogs. The owner was very accommodating and responsive and the guesthouse suited our needs perfectly. I would definitely recommend this."

More cheap stays in Drew

Motel 6 Cleveland, MS - Delta State University

721 N Davis Ave Cleveland MS

$73 nightly

$80 total

Oct 25 - Oct 26

Total with taxes and fees

8.2/10 Very Good! (338 reviews)

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS

$80 nightly

$87 total

Oct 23 - Oct 24

Total with taxes and fees

6/10 (437 reviews)

Quality Inn Clarksdale

818 South State Street Clarksdale MS

$80 nightly

$87 total

Nov 12 - Nov 13

Total with taxes and fees

Holiday Inn Express Hotel & Suites Cleveland by IHG

808 N Davis Ave Cleveland MS

$113 nightly

$123 total

Nov 21 - Nov 22

Total with taxes and fees

7.8/10 Good! (1,003 reviews)

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS

$130 nightly

$142 total

Nov 1 - Nov 2

Total with taxes and fees

8.2/10 Very Good! (417 reviews)

Travelers Hotel

212 3rd St Clarksdale MS

$144 nightly

$157 total

Nov 1 - Nov 2

Total with taxes and fees

9.8/10 Exceptional! (323 reviews)

Hotels in Drew with star-rating

Frequently asked questions

What is the best area to stay in Drew?

The best area to stay in Drew, Mississippi, is near the town center, particularly along South Main Street.This central area offers convenient access to local establishments. It features a few blocks of businesses and residences, giving you a sense of local life. You'll find the town's primary amenities concentrated here, making it easy to navigate on foot.For travelers seeking a quiet and authentic experience, staying near the town center is ideal. It provides a direct connection to the community, allowing you to easily visit local eateries or shops.

When is the best time to go to Drew?

The best time to visit Drew, Mississippi, is during the spring (late March to May) and fall (September to October) months.These seasons offer pleasant weather with mild temperatures and lower humidity, making it comfortable for exploring the area. Springtime brings blooming flora, while the fall delivers crisp air and colorful foliage, enhancing the scenic beauty of the Mississippi Delta.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Drew.

How much is the nightly rate at a Drew hotel?

Prices for hotels in Drew often vary, but you can find a great deal from $50 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Things to do in Mississippi Delta

Find hotels in Drew, MS from $50

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Drew

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Drew hotels

1. Lyric Hotel West End, Trademark Collection by Wyndham

2. Cotton House, Cleveland, a Tribute Portfolio Hotel

3. Motel 6 Cleveland, MS - Delta State University

4. SureStay Plus Hotel by Best Western Greenwood

5. Motel 6 Greenwood, MS

6. Hampton Inn Clarksdale

7. Quality Inn Clarksdale

8. Holiday Inn Express Hotel & Suites Cleveland by IHG

9. Travelers Hotel

10. Holiday Inn Express & Suites - Greenwood by IHG

11. Quality Inn Indianola

12. Super 8 by Wyndham Indianola

13. Hampton Inn Greenwood

14. Ruleville Inn By OYO

15. Americas Best Value Inn & Suites Clarksdale

16. Rodeway Inn

17. Americas Best Value Inn Indianola

18. c towninn and suites

19. Americas Best Value Inn & Suites Greenwood

20. The Delta Lodge - Greenwood, MS

Compare top hotels in Drew

Lyric Hotel West End, Trademark Collection by Wyndham

Cotton House, Cleveland, a Tribute Portfolio Hotel

Motel 6 Cleveland, MS - Delta State University

SureStay Plus Hotel by Best Western Greenwood

Motel 6 Greenwood, MS

Top Drew Hotel Reviews

Auberge Clarksdale Blues Hostel

Holiday Inn Express Hotel & Suites Cleveland by IHG

Motel 6 Cleveland, MS - Delta State University

Hampton Inn Clarksdale

Travelers Hotel

The Sunflower Penthouse on the River in Clarksdale

Only a mile from historic downtown Clarksdale!

Sunset Log Cabin

Honnoll's High Cotton Guesthouse

More cheap stays in Drew

Motel 6 Cleveland, MS - Delta State University

Americas Best Value Inn & Suites Clarksdale

Quality Inn Clarksdale

Holiday Inn Express Hotel & Suites Cleveland by IHG

Hampton Inn Clarksdale

Travelers Hotel

Hotels in Drew with star-rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app