Eastern Iowa, IA

Travel Guide

Eastern Iowa
Eastern Iowa
Eastern Iowa
Eastern Iowa
Eastern Iowa

Explore the banks of the great Mississippi River and discover the life that has erupted from it. Museums, panoramas and plenty of fresh air await you.

Eastern Iowa is bordered by the snaking Mississippi River. Life has long revolved around the massive river, with the region’s nature, history and culture all entwined with it. Visit Eastern Iowa for a flavor of the Midwest, where tradition, astounding natural beauty and welcoming residents characterize the region.

Begin your explorations at the charming city of Dubuque. Learn about the vast river and its many different residents at the impressive National Mississippi River Museum and Aquarium, part of a sprawling riverfront development. The museum and aquarium depict all types of life existing along the waterway, from steamboat sailors to aquatic species.

Visit the Mines of Spain Recreation Area just south of the city, which offers a beautiful panorama of the Mississippi as well as a maze of walking trails and picnic spots. Back in the city, ride the 19th-century Fenelon Place funicular for incredible city views. North of the city, the Dubuque Arboretum and Botanical Gardens is a delightful place to relax and breathe in fresh Iowa air.

Outside Dubuque, Eastern Iowa is steeped in tradition. Tour the quaint town of Dyersville, the set for the baseball movie Field of Dreams, before heading south to Davenport. One of the main attractions here is the Figge Art Museum, which includes a collection of Midwest paintings by Iowa native Grant Wood, painter of the famous American Gothic painting.

Dubuque and Davenport both have regional airports and are a 3-hour drive from the international airport in Des Moines, the state capital. In addition, Eastern Iowa offers several scenic byways and historic routes. Follow one of these designated routes to explore the patchwork countryside where pastureland, rolling hills and the Mississippi River create a truly picturesque landscape.

Visit pretty little villages and communities where residents treat guests like family. Attend the lively local festivals or hop on a riverboat for a romantic trip down the famous river.

Hotel Julien Dubuque

Hotel Julien Dubuque

3.5 out of 5
200 Main Street Dubuque IA
$124 nightly
The price is $140 total per night from Jun 30 to Jul 1
$140 total
Jun 30 - Jul 1
Total with taxes and fees
Book a stay at this spa hotel in Dubuque. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the restaurant and the helpful staff in our ...
9.2/10 Wonderful! (1,869 reviews)
"Great stay at this historical property in an amazing location! Most of downtown Dubuque is within walking distance as is the riverfront, casino, and museums. Wonderful huge room with river views in addition to spacious fitness center and fun bar on site. Will stay here again in future."

Reviewed on Jun 23, 2026

Hotel Julien Dubuque
Isle Casino Hotel - Waterloo - A Caesars Rewards Destination

Isle Casino Hotel - Waterloo - A Caesars Rewards Destination

3 out of 5
777 Isle of Capri Blvd Waterloo IA
$63 nightly
The price is $84 total per night from Jul 22 to Jul 23
$84 total
Jul 22 - Jul 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Waterloo. Enjoy free WiFi, a casino, and a 24-hour fitness center. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,009 reviews)
"It was great and a a lot of fun at the casino"

Reviewed on Jun 21, 2026

Isle Casino Hotel - Waterloo - A Caesars Rewards Destination
Hyatt Place Iowa City Downtown

Hyatt Place Iowa City Downtown

3 out of 5
255 E Court St Iowa City IA
$110 nightly
The price is $125 total per night from Jun 30 to Jul 1
$125 total
Jun 30 - Jul 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Iowa City. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (1,554 reviews)
"Rooms are clean. Staff friendly and helpful. Hotel was clean except showers and tiling need sprucin up ad well as the carpet throughout the hotel. Also doors in neibori g rooms were way to loud when people go in and out always making a loud bang every time."

Reviewed on Jun 21, 2026

Hyatt Place Iowa City Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos

3 out of 5
2372 N County Road 900 Nauvoo IL
Book a stay at this business-friendly condo in Nauvoo. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (439 reviews)
"Nauvoo Villas have been well maintained and had everything that we needed for our recent family vacation to Nauvoo. It was a quick 5 minute drive from downtown."

Reviewed on Jun 19, 2026

Nauvoo Vacation Villas & Condos
1850 Cabin Home - Large BYard-Waterfall- 22' Movie Screen-Family-Event Travelers

1850 Cabin Home - Large BYard-Waterfall- 22' Movie Screen-Family-Event Travelers

East Dubuque IL
Stay at this vacation home in East Dubuque. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Dubuque Star Brewing Company ...
9.6/10 Exceptional! (37 reviews)
"Great place, friendly host, close to town!"

Reviewed on Jun 17, 2026

1850 Cabin Home - Large BYard-Waterfall- 22' Movie Screen-Family-Event Travelers
The Barn House Lodge

The Barn House Lodge

Spillville IA
Stay at this vacation home in Spillville. Enjoy free WiFi, laundry facilities, and patios. Popular attractions St Wenceslaus Catholic Church and Bily Clocks ...
10/10 Exceptional! (80 reviews)
"Great location but a little hard to find."

Reviewed on Jun 14, 2026

The Barn House Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Cities near Eastern Iowa

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