Eastern Iowa Vacation Rentals

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Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Eastern Iowa vacation rentals

Exterior detail
Minutes from anywhere

Apartment in Moline

Minutes from anywhere
10.0 out of 10, Exceptional, (124)
"We really enjoyed our stay and the location was perfect!"
United States
Brittany S.
$76 nightly
The price is $80
Jan 20 - Jan 21, 2026
Total with taxes and fees
Minutes from anywhere
Dining
Nauvoo Country Cottage - Sleeps 12

Cottage in Niota

Nauvoo Country Cottage - Sleeps 12
9.6 out of 10, Exceptional, (84)
"Great place to stay!!"
United States
Lisa G.
$145 nightly
The price is $154
Jan 8 - Jan 9, 2026
Total with taxes and fees
Nauvoo Country Cottage - Sleeps 12
Interior
Historic Cottage in LeClaire w/full river views and 3 decks. Dogs welcome

Cottage in LeClaire

Historic Cottage in LeClaire w/full river views and 3 decks. Dogs welcome
10.0 out of 10, Exceptional, (79)
"Cozy and beautiful space that we enjoyed immensely!"
United States
Nadine Z.
$220 nightly
The price is $247
Dec 28 - Dec 29
Total with taxes and fees
Historic Cottage in LeClaire w/full river views and 3 decks. Dogs welcome
Terrace/patio
Mississippi River Cabin

Cabin in Bellevue

Mississippi River Cabin
10.0 out of 10, Exceptional, (37)
"We loved the place great location very clean and we will be back . "
United States
Mary A.
$189 nightly
The price is $212
Dec 29 - Dec 30
Total with taxes and fees
Mississippi River Cabin
Exterior
The Iowa Auntie’s 👩🏼‍🌾Quirky Little Shanty. Better than staying with family! 😉

Vacation Home in Wellman

The Iowa Auntie’s 👩🏼‍🌾Quirky Little Shanty. Better than staying with family! 😉
10.0 out of 10, Exceptional, (46)
"Very friendly host"
United States
Alex B.
$88 nightly
The price is $92
Dec 31 - Jan 1, 2026
Total with taxes and fees
The Iowa Auntie’s 👩🏼‍🌾Quirky Little Shanty. Better than staying with family! 😉
Front of property
Nauvoo Vacation Villas & Condos

Condo in Nauvoo

Nauvoo Vacation Villas & Condos
3.0 star property
9.8 out of 10, Exceptional, (424)
"Very nice comfortable property"
United States
Carie
$136 nightly
The price is $144
Dec 25 - Dec 26
Total with taxes and fees
Nauvoo Vacation Villas & Condos
Fridge, microwave, oven, stovetop
Butterfly Park Retreat #3 - Centrally located to Decorah's Top Attractions!

Apartment in Decorah

Butterfly Park Retreat #3 - Centrally located to Decorah's Top Attractions!
10.0 out of 10, Exceptional, (14)
"Property had a lot of great amenities and we had a great stay. we will be back next year!"
United States
Harrison P.
$166 nightly
The price is $186
Dec 25 - Dec 26
Total with taxes and fees
Butterfly Park Retreat #3 - Centrally located to Decorah's Top Attractions!
Bar (on property)
Best Location in town!!! Steps from coffee, bars, shops, river and Czech - Pets ! Arcade

Vacation Home in Cedar Rapids

Best Location in town!!! Steps from coffee, bars, shops, river and Czech - Pets ! Arcade
9.6 out of 10, Exceptional, (28)
"We stayed following a business party. It was perfect. Very clean and decorated nicely. We enjoyed the porch. Loved the coffee. "
United States
Anonymous traveler
$172 nightly
The price is $192
Jan 19 - Jan 20, 2026
Total with taxes and fees
Best Location in town!!! Steps from coffee, bars, shops, river and Czech - Pets ! Arcade
2 bedrooms, in-room safe, desk, iron/ironing board
Adorable Cottage in small town of Marion. Just a few blocks from Uptown

Vacation Home in Marion

Adorable Cottage in small town of Marion. Just a few blocks from Uptown
9.8 out of 10, Exceptional, (25)
"Excellent stay, very comfortable and the owners cover every base and more to make sure. We drove over 1000 miles to meet old friends and staying here made the trip so awesome! Highly recommend. "
United States
Craig D.
$205 nightly
The price is $230
Dec 30 - Dec 31
Total with taxes and fees
Adorable Cottage in small town of Marion. Just a few blocks from Uptown
Exterior
Relax on the River and Enjoy Southeast Iowa's Beauty

Cabin in Keosauqua

Relax on the River and Enjoy Southeast Iowa's Beauty
9.8 out of 10, Exceptional, (170)
"A nice little cabin on the Des Moines River with many historical sites close at hand."
United States
Charles K.
$171 nightly
The price is $180
Jan 7 - Jan 8, 2026
Total with taxes and fees
Relax on the River and Enjoy Southeast Iowa's Beauty
Fridge, microwave, oven, stovetop
Beautiful Riverview Apt Located in Downtown Fort Madison

Apartment in Fort Madison

Beautiful Riverview Apt Located in Downtown Fort Madison
10.0 out of 10, Exceptional, (5)
"I was here for a couple weeks for work, and Rebecca was responsive with any questions, very friendly, and an excellent host!"
United States
Sam G.
$186 nightly
The price is $208
Dec 27 - Dec 28
Total with taxes and fees
Beautiful Riverview Apt Located in Downtown Fort Madison
Terrace/patio
Riverfront Cabin:Wrap Around Deck & 3 Season Room

Vacation Home in Moline

Riverfront Cabin:Wrap Around Deck & 3 Season Room
9.4 out of 10, Exceptional, (34)
"House was very nice - nicely decorated and maintained. Wasn’t a fan of window units (they were kinda stinky and loud)."
United States
Katie K.
$217 nightly
The price is $228
Jan 7 - Jan 8, 2026
Total with taxes and fees
Riverfront Cabin:Wrap Around Deck & 3 Season Room
Smart TV, stereo
Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.

Vacation Home in Bellevue

Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
9.6 out of 10, Exceptional, (108)
"Great place to stay. "
United States
Michael
$176 nightly
The price is $197
Dec 25 - Dec 26
Total with taxes and fees
Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Smart TV
The Nest: Beautiful Apartment Style Lodging In The Heart Of Downtown Decorah.

Apartment in Downtown Decorah

The Nest: Beautiful Apartment Style Lodging In The Heart Of Downtown Decorah.
9.6 out of 10, Exceptional, (172)
"This is a nice little apartment in downtown. Great location to enjoy a walk through town and Saturday morning Farmers Market. "
United States
SALLY S.
$166 nightly
The price is $185
Dec 28 - Dec 29
Total with taxes and fees
The Nest: Beautiful Apartment Style Lodging In The Heart Of Downtown Decorah.
Property grounds
Private entrance/space. Peaceful getaway. Close to events. King bed. Amenities!

Apartment in Dubuque

Private entrance/space. Peaceful getaway. Close to events. King bed. Amenities!
9.6 out of 10, Exceptional, (25)
"Check in was easy and the place was very cozy and cute! "
United States
McKenna W.
$110 nightly
The price is $123
Dec 25 - Dec 26
Total with taxes and fees
Private entrance/space. Peaceful getaway. Close to events. King bed. Amenities!
Smart TV, fireplace
Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex

Vacation Home in Davenport

Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex
10.0 out of 10, Exceptional, (36)
"Nice place, as advertised. "
United States
Joseph T.
$274 nightly
The price is $307
Jan 2 - Jan 3, 2026
Total with taxes and fees
Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex
1 bedroom, WiFi
Lindell - Downtown CF Studio - King Bed! 510

Apartment in Cedar Falls

Lindell - Downtown CF Studio - King Bed! 510
8.0 out of 10, Very Good, (28)
"Great place and great hosts! The location to Main Street is perfect, will definitely book again on our next trip!"
United States
Darren M.
$95 nightly
The price is $106
Dec 26 - Dec 27
Total with taxes and fees
Lindell - Downtown CF Studio - King Bed! 510
Smart TV, fireplace
Log Cabin/ w hot tub, outdoor pool & pool table

Cabin in Lansing

Log Cabin/ w hot tub, outdoor pool & pool table
9.8 out of 10, Exceptional, (58)
"Great cabin for multiple families to stay! Spacious and gorgeous area! "
United States
Veronica M.
$217 nightly
The price is $243
Jan 7 - Jan 8, 2026
Total with taxes and fees
Log Cabin/ w hot tub, outdoor pool & pool table
Interior
Country Club Cottages - 1703

Vacation Home in Washington

Country Club Cottages - 1703
2.0 star property
9.8 out of 10, Exceptional, (17)
"Love staying here when we visit South East Iowa!"
United States
Andrea B.
$157 nightly
The price is $165
Dec 29 - Dec 30
Total with taxes and fees
Country Club Cottages - 1703
Terrace/patio
Historic Farm House called Oak Cliff w/ spectacular view of Mississippi River

Vacation Home in Cordova

Historic Farm House called Oak Cliff w/ spectacular view of Mississippi River
10.0 out of 10, Exceptional, (41)
"We had a great stay. Worked well for biking."
United States
Anonymous traveler
$238 nightly
The price is $252
Jan 2 - Jan 3, 2026
Total with taxes and fees
Historic Farm House called Oak Cliff w/ spectacular view of Mississippi River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Iowa Hotel Reviews

Graduate by Hilton Iowa City

Graduate by Hilton Iowa City

10/10 Excellent
"Everything was great."
Sharon 2-night trip
Posted 1 day ago
Graduate by Hilton Iowa City

Find out more about Eastern Iowa

Everything you need to know about Eastern Iowa vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Iowa vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Iowa vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Eastern Iowa vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Iowa. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Eastern Iowa in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $80 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Eastern Iowa rentals

At Expedia, we put the best Eastern Iowa vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Iowa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Iowa vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Iowa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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