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Compare 2,202 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Río San Francisco hotels

Mandarin Oriental, Santiago

5.0 star property
9.2 out of 10, Wonderful, (891)
"10/10; best hotel in Santiago. "
$199 nightly
The price is $199
Sep 21 - Sep 22
Mandarin Oriental, Santiago

Wyndham Santiago Pettra

4.5 star property
9.0 out of 10, Wonderful, (532)
"Great hotel Clean and very comfortable beds."
$119 nightly
The price is $119
Sep 7 - Sep 8
Wyndham Santiago Pettra

Le Rêve Boutique Hotel

4.0 star property
9.8 out of 10, Exceptional, (447)
"Great location, we walked to San Cristobal Hill and local dining and took a short Uber ride to the Palace, Plaza del Armas and other downtown sites. Jose organized pickup from the airport and transfers to and from Valle Nevado. The breakfast was good, tea, coffee and water available all day. Great stay."
$194 nightly
The price is $194
Sep 21 - Sep 22
Le Rêve Boutique Hotel

Refugio Atreyu

3.0 star property
9.2 out of 10, Wonderful, (38)
"Staff are so friendly and kind."
$118 nightly
The price is $118
Sep 4 - Sep 5
Refugio Atreyu

Gran Parador Apartments Ski Center El Colorado Farellones.

3.5 star property
8.2 out of 10, Very Good, (19)
"This property is very close to the lift but that is about it.... We got there and had a snow storm and lost power for 3 days and we were not offer an explanation, when I asked when we could expect the lights to be back they almost took offense to answer and said they had no ideia but I should be happy they had a small generator and pawer the shower and one outlet in the kitchen. I get it that you can control a snow storm but they weren't prepared at all. So we couldn't use any facilities at the...
$336 nightly
The price is $336
Sep 1 - Sep 2
Gran Parador Apartments Ski Center El Colorado Farellones.

Sel Lodge hotel y spa

4.0 star property
9.2 out of 10, Wonderful, (39)
"The SEL Lodge hotel y spa is an incredible place to stay. The views are magnificent, the room was beautiful with a spacious balcony And even a hot tub in the room. My friend who is local was very impressed I found such a great place. 10 out of 10!!"
$70 nightly
The price is $70
Sep 9 - Sep 10
Sel Lodge hotel y spa

Hotel Cumbres Lastarria

4.0 star property
9.6 out of 10, Exceptional, (866)
"Great stay! "
$121 nightly
The price is $121
Sep 10 - Sep 11
Hotel Cumbres Lastarria

The Singular Santiago

5.0 star property
9.6 out of 10, Exceptional, (640)
"Charming hotel, excellent service, Some good eating places close by, felt safe "
$230 nightly
The price is $230
Sep 1 - Sep 2
The Singular Santiago

Novotel Santiago Providencia

4.0 star property
9.2 out of 10, Wonderful, (882)
"Excelente"
$97 nightly
The price is $97
Sep 19 - Sep 20
Novotel Santiago Providencia

Hotel Eco Boutique Bidasoa

4.0 star property
9.2 out of 10, Wonderful, (229)
"Fantastic property near the main attractions but far enough for calm and tranquility. "
$147 nightly
The price is $147
Sep 6 - Sep 7
Hotel Eco Boutique Bidasoa

Solace Hotel Santiago

4.0 star property
9.4 out of 10, Exceptional, (1014)
"Good location and friendly staff "
$92 nightly
The price is $92
Sep 7 - Sep 8
Solace Hotel Santiago

NH Collection Santiago Casacostanera

4.0 star property
8.6 out of 10, Excellent, (272)
"Great location, superb dining, awesome shopping "
$117 nightly
The price is $117
Sep 19 - Sep 20
NH Collection Santiago Casacostanera

Hotel Boutique Castillo Rojo

4.0 star property
9.6 out of 10, Exceptional, (611)
"Really fun stay good location"
$112 nightly
The price is $112
Sep 9 - Sep 10
Hotel Boutique Castillo Rojo

ICON Hotel

4.0 star property
8.6 out of 10, Excellent, (1004)
"Location and excellent costumer service."
$124 nightly
The price is $124
Sep 23 - Sep 24
ICON Hotel

Hotel Sommelier Boutique

3.5 star property
9.0 out of 10, Wonderful, (622)
"Great property nice roof top. "
Hotel Sommelier Boutique

Hyatt Place Santiago/Vitacura

3.5 star property
9.0 out of 10, Wonderful, (1006)
"Nice hotel, although rooms need a bit of an update, but common areas pretty good and very nice staff. Good breakfast too! "
$119 nightly
The price is $119
Sep 6 - Sep 7
Hyatt Place Santiago/Vitacura

Sheraton Santiago Hotel and Convention Center

4.0 star property
8.4 out of 10, Very Good, (619)
"Hotel is very well located easy to tourist from there, people are very nice and friendly, I love the variety options for breakfast and even I could have my oatmeal with all the seeds and granolas I like. Hotel is close to Costanera Center mall and all the restaurants you can enjoy. Happy to choose it. "
$116 nightly
The price is $116
Sep 18 - Sep 19
Sheraton Santiago Hotel and Convention Center

Pullman Santiago El Bosque

4.5 star property
9.0 out of 10, Wonderful, (824)
"Great staff and the food was of a very high standard."
$88 nightly
The price is $88
Sep 19 - Sep 20
Pullman Santiago El Bosque

DoubleTree by Hilton Santiago Kennedy

4.0 star property
9.0 out of 10, Wonderful, (790)
"Great place to stay"
$103 nightly
The price is $103
Sep 5 - Sep 6
DoubleTree by Hilton Santiago Kennedy

Noi Vitacura

5.0 star property
8.6 out of 10, Excellent, (523)
"Great hotel in Santiago! The rooftop bar has incredible views of the city and Andes, and the location in Vitacura is perfect with lots of nice restaurants nearby. Staff were friendly and helpful. We just wish our room had been on a higher floor with a view—it would have made the stay even better. Overall, highly recommend! "
$194 nightly
The price is $194
Sep 15 - Sep 16
Noi Vitacura
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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