Find hotels in Santee, SC from $46

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Compare 304 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (615)
"Nice place to stay"
Canada
Tanya
$95 nightly
The price is $106
Dec 7 - Dec 8
Total with taxes and fees
Tru By Hilton Santee

Hampton Inn Santee-I-95

2.5 star property
Santee
9.6 out of 10, Exceptional, (1007)
"Very nice hotel, very clean and super friendly staff. "
United States
Ashley
$112 nightly
The price is $124
Dec 7 - Dec 8
Total with taxes and fees
Hampton Inn Santee-I-95

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1405)
"The best stay"
United States
Terez
$80 nightly
The price is $89
Nov 30 - Dec 1
Total with taxes and fees
Baymont by Wyndham Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1012)
"Very welcoming, hotel has a clean and friendly presentation."
Canada
VALERIE AND JOHN
$121 nightly
The price is $134
Dec 7 - Dec 8
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee

Comfort Inn & Suites Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1005)
"Service was great breakfast was good"
United States
Gary
$99 nightly
The price is $109
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

2.0 star property
Santee
7.0 out of 10, Good, (671)
"Good location "
United States
Jessica
$61 nightly
The price is $68
Dec 16 - Dec 17
Total with taxes and fees
Travelodge by Wyndham Santee

Holiday Inn Santee by IHG

3.0 star property
Santee
8.2 out of 10, Very Good, (968)
"Great hotel w"
United States
Elizabeth
$111 nightly
The price is $123
Dec 8 - Dec 9
Total with taxes and fees
Holiday Inn Santee by IHG

Best Western Plus Santee Inn

2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
$118 nightly
The price is $131
Dec 7 - Dec 8
Total with taxes and fees
Best Western Plus Santee Inn

Quality Inn & Suites

2.5 star property
Santee
6.0 out of 10, (448)
"Great place. Excellent people. Great service"
United States
Jesse
$59 nightly
The price is $66
Dec 7 - Dec 8
Total with taxes and fees
Quality Inn & Suites

Ramada by Wyndham Santee I-95

2.0 star property
Santee
6.2 out of 10, (540)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
$78 nightly
The price is $86
Dec 14 - Dec 15
Total with taxes and fees
Ramada by Wyndham Santee I-95

Red Roof Inn Santee

2.0 star property
Santee
6.6 out of 10, (635)
"It's a good stop for the price "
United States
Martin
$70 nightly
The price is $78
Nov 30 - Dec 1
Total with taxes and fees
Red Roof Inn Santee

Super 8 by Wyndham Santee

2.0 star property
Santee
6.8 out of 10, (437)
"The nicest bathroom on our 12 day trip"
United States
Rhonda
$75 nightly
The price is $83
Nov 30 - Dec 1
Total with taxes and fees
Super 8 by Wyndham Santee

Econo Lodge

2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
$63 nightly
The price is $70
Dec 24 - Dec 25
Total with taxes and fees
Econo Lodge

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1010)
"Staff was friendly, room was clean and quiet. recommend this property."
United States
Janet
$103 nightly
The price is $115
Dec 7 - Dec 8
Total with taxes and fees
Tru by Hilton Orangeburg

Comfort Inn & Suites Orangeburg

2.5 star property
Orangeburg
8.0 out of 10, Very Good, (540)
"The room was clean, and the bed was comfortable. The staff was friendly and welcoming. The breakfast was pretty good, too."
United States
LINA
$95 nightly
The price is $106
Dec 7 - Dec 8
Total with taxes and fees
Comfort Inn & Suites Orangeburg

Spark by Hilton Orangeburg

2.5 star property
Orangeburg
7.8 out of 10, Good, (1005)
"Clean, quiet, nice place for an overnight stay"
United States
Joseph
$87 nightly
The price is $97
Dec 7 - Dec 8
Total with taxes and fees
Spark by Hilton Orangeburg

SureStay Hotel by Best Western Manning

2.5 star property
Manning
8.6 out of 10, Excellent, (1010)
"Staff was very courteous "
United States
Dayshia
$89 nightly
The price is $99
Dec 4 - Dec 5
Total with taxes and fees
SureStay Hotel by Best Western Manning

Days Inn by Wyndham St George

2.5 star property
St. George
7.6 out of 10, Good, (1002)
"Helpful folks at check in and super clean room. "
United States
Peter
$73 nightly
The price is $81
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham St George

Fairfield Inn by Marriott Orangeburg

2.5 star property
Orangeburg
8.4 out of 10, Very Good, (683)
"Staff was nice. Room is ok "
United States
Calvin
$84 nightly
The price is $93
Dec 7 - Dec 8
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg

Days Inn by Wyndham Orangeburg

2.0 star property
Orangeburg
5.6 out of 10, (713)
"Clean room quiet stay. "
United States
Sammy
$42 nightly
The price is $46
Dec 2 - Dec 3
Total with taxes and fees
Days Inn by Wyndham Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Hotels in Santee with star-rating

Find out more about Santee

Top reasons to visit Santee

  • Outdoor Recreation: Santee is a paradise for outdoor enthusiasts, offering activities like hiking, fishing, and boating in its scenic parks and lakes.
  • Golfing Excellence: Play at renowned golf courses, making Santee a prime destination for golf vacations.
  • Natural Beauty: The stunning landscapes and serene waters create a picturesque setting perfect for relaxation and exploration.
  • Local Nightlife: Experience Santee's vibrant nightlife, offering a mix of entertainment options for a memorable evening.
  • Welcoming Accommodations: Enjoy a variety of comfortable lodging options tailored to suit diverse needs and preferences.

Find great hotels in and around Santee

Discover the perfect blend of comfort and hospitality in Santee, South Carolina. Whether you're looking for pet-friendly options, business-themed accommodations, or LGBTQIA welcoming stays, Santee offers a variety of hotels and motels to suit your needs. From cozy inns to spacious suites, you’ll find the ideal lodging for a memorable vacation experience.

  • Baymont by Wyndham Santee: Embrace a cozy and welcoming atmosphere at Baymont by Wyndham Santee, ideal for travelers seeking a pet-friendly, business-themed getaway. This hotel provides a perfect blend of comfort and practicality, featuring amenities tailored to business needs. Guests can enjoy a variety of services, including a dedicated business center. The property is also pet-friendly, allowing dogs and cats with certain restrictions, making it a great choice for those traveling with furry companions. With its inviting ambiance and convenient facilities, Baymont by Wyndham Santee is designed to cater to both leisure and business travelers alike.
  • Fairfield Inn by Marriott Orangeburg: Located 19 miles from Santee, the Fairfield Inn by Marriott Orangeburg stands as a beacon for business travelers and the LGBTQIA community. This hotel boasts a welcoming environment enhanced by its affiliation with LGBTQI travel guides. With a 24-hour business center, guests can efficiently handle their work commitments while enjoying comfortable accommodations. The hotel’s commitment to inclusivity and its focus on providing essential business amenities make it an excellent choice for both work and relaxation.
  • Best Western Plus Santee Inn: Discover a blend of comfort and professionalism at Best Western Plus Santee Inn, perfectly situated in Santee. This hotel is not only pet-friendly but also offers extensive business facilities, including meeting rooms, a business center, and conference space. With amenities catering to both four-legged guests and business needs, it creates an ideal environment for all types of travelers. The hotel's attention to service and convenience ensures a pleasant stay, whether you're in town for work or leisure.

Where to stay near Santee

Experience the charm of Santee, South Carolina, where serene waters meet stunning landscapes, perfect for outdoor lovers and romantic getaways. Enjoy family-friendly excursions and friendly locals while exploring this budget-friendly destination. Whether you're teeing off at top-notch golf courses or soaking in the tranquil atmosphere, Santee offers a delightful escape filled with Southern hospitality and picturesque scenery. Make lasting memories in this hidden gem of the Palmetto State.

  • Summerton: Situated 11 miles away from Santee, Summerton is a charming city that invites visitors with its picturesque outdoor experiences and romantic scenery. Known for its recreational areas, golf courses, and stunning lakes, Summerton is ideal for those looking to unwind in nature. A highlight of the area is the nearby national state park, offering trails and breathtaking views that attract both adventurers and those seeking tranquility. With visitor numbers peaking in March to April and July, it’s a great time to enjoy the vibrant local scene.
  • Vance: Located just 5 miles from Santee, Vance is a delightful city known for its highly seasonal tourist influx. Visitors flock here during the peak months of March to April and July, drawn by the area's scenic beauty and outdoor activities. Golf enthusiasts can enjoy excellent courses, while the tranquil lakes and nearby islands provide perfect spots for relaxation and exploration. Vance’s proximity to a national state park enhances its appeal, making it a fantastic destination for couples and nature lovers alike.
  • Elloree: Elloree, located 6 miles from Santee, is a quaint city with a steady flow of visitors throughout the year. The area is particularly popular in March, July, and September, when outdoor enthusiasts and romantics alike seek its natural beauty. With access to recreational areas and well-maintained golf courses, Elloree offers plenty of opportunities for leisure and adventure. The nearby lakes and national parks serve as stunning backdrops for outdoor activities, making it a must-visit on your South Carolina itinerary.

Things to do in and around Santee

Santee, South Carolina, is perfect for outdoor enthusiasts and couples seeking a romantic getaway. Enjoy various activities, including exploring the scenic recreational areas, playing at renowned golf courses, and indulging in a golf vacation stay. For those interested in fishing, the striped bass are a highlight. Don't miss the chance to experience the local nightlife options, making Santee an ideal destination for a memorable day trip or an extended vacation.

Shopping

Santee offers a charming shopping experience with local shops and boutiques. If you're up for a drive, head to Pocalla Crossing Shopping Center, located 27 miles away, featuring a variety of stores, or visit Bee City, a unique shop 30 miles from Santee for some special gifts.

Recreation

Experience a round of golf at Santee Cooper Country Club, where the outdoor vibes enhance your game. For relaxation, explore the serene Santee National Wildlife Refuge, just 4 miles away, or enjoy recreational activities at Patriots Sports Plex, located 31 miles from Santee, fostering wellness and tranquility.

Adventure

Santee State Park offers picturesque hiking trails, fishing spots, and opportunities for kayaking on Lake Marion. Explore the scenic beauty while spotting local wildlife or enjoy a picnic by the water. For thrill-seekers, the nearby Santee Cooper Lakes provide exciting boating and jet skiing adventures.

Nightlife

Santee boasts a laid-back nightlife scene, perfect for relaxing after a day of exploration. Enjoy live music at local bars, savor delicious Southern cuisine, or try your luck at nearby casinos. The warm atmosphere and friendly locals make for an enjoyable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santee

Santee, South Carolina, offers budget-friendly travel options for visitors. Enjoy free entry to local attractions like Taw Caw Creek, and consider visiting between December and February for lower accommodation rates. Mondays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to find affordable hotels by sorting prices from lowest to highest, and consider package deals that combine flights and activities for additional savings. Joining Expedia's One Key membership can unlock exclusive discounts and help you earn OneKeyCash for future bookings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool makes it easy to customize your travel experience by choosing your budget, desired location, and additional preferences. You can arrange your search results to display hotel prices from lowest to highest, allowing you to find the most affordable options first. Additionally, you have the option to narrow down your choices by hotel type; for instance, if you select the Eco-certified filter, you'll be shown sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santee with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around Santee

Santee, South Carolina, offers an ideal setting for outdoor enthusiasts and couples seeking a romantic getaway. With stunning scenery, visitors can explore local attractions such as Santee State Park, picturesque lakes, and nearby islands. Whether you're looking for adventure or relaxation, Santee's natural beauty and recreational opportunities promise an unforgettable experience for travelers seeking a beach and nature-focused vacation.

  • Santee State Park: Experience the great outdoors at Santee State Park, where adventure awaits in the form of hiking, fishing, and camping amidst stunning natural scenery. The park's serene atmosphere is perfect for nature lovers and those seeking relaxation.
  • Santee Indian Mound and Fort Watson Site: Just 4 miles from Santee, this historic site offers a glimpse into the area's rich Native American heritage. Explore the ancient Indian mound and learn about the strategic importance of Fort Watson during the Revolutionary War.
  • Taw Caw Creek: About 9 miles away, Taw Caw Creek is a picturesque lake that invites visitors to enjoy a beach-like atmosphere. Perfect for romantic outings, picnics, or simply soaking in the scenic beauty, it’s an ideal spot to unwind.

Best time to go to Santee

The best time to visit Santee can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santee falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Santee falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighAverage
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighSlightly High
May72.0°F (22.2°C)Light RainMostly SunnyAverageSlightly High
June78.6°F (25.9°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighAverage
August79.9°F (26.6°C)Light RainMostly SunnyAverageAverage
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowSlightly High
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Santee

Traveling to Santee, South Carolina, is convenient, with two major airports nearby. Charleston International Airport (CHS) is located 49 miles from Santee, with luxury hotels like The Charleston Place, The Dewberry Charleston, and Hotel Bennett, all 9 miles from the airport, offering transfer services. Columbia Metropolitan Airport (CAE) is also 49 miles away, providing access to well-rated hotels such as Graduate by Hilton Columbia SC, Doubletree by Hilton Columbia, and Marriott Columbia, situated 6 to 7 miles from the airport. Both airports ensure easy access to Santee for a delightful vacation experience.

Frequently asked questions

What are the best hotels in Santee that travelers recommend?
Holiday Inn Santee by IHG stands out as a top choice for travelers, earning a review score of 8.2. This hotel combines comfort with convenience, making it a great option for groups and solo travelers. With spacious rooms and attentive service, guests feel right at home. The hotel features a ballroom for events and room service, ensuring that all your needs are met without hassle.
What are the best family hotels in Santee?
Holiday Inn Santee by IHG stands out as an excellent family-friendly option in Santee, South Carolina, with an excellent traveler review rating of 8.2. This hotel offers spacious rooms that include cribs and connecting rooms, making it easy for families to stay close together while enjoying their own space. Find more child-friendly accommodations in Santee.
What are the top pet-friendly hotels in Santee?
Holiday Inn Santee by IHG is a fantastic option for pet-friendly travelers seeking a blend of comfort and convenience. This hotel welcomes small pets, ensuring that your furry friends can join in on the adventure. Guests appreciate the inviting indoor pool, great for a refreshing dip after a day of exploring, and the nearby golf course offers a delightful opportunity for those looking to tee off amidst beautiful scenery. See more pet-friendly hotels in Santee.
What are the best budget hotels in Santee?
For budget-conscious travelers seeking comfort and convenience in Santee, the Fairfield Inn & Suites by Marriott Santee stands out with an impressive guest review rating of 9.8. This hotel offers a delightful array of amenities, including complimentary breakfast options and free WiFi, ensuring a straightforward stay. Families will appreciate the outdoor pool, accessible fitness center, and the availability of cribs and highchairs, making it a welcoming environment for kids.

Another excellent choice is the Hampton Inn Santee-I-95, rated 9.6 by guests. This property also features an outdoor seasonal pool and offers free breakfast, creating the great start to a day of exploration. With spacious rooms equipped with cribs and rollaway beds, families can comfortably settle in without worry.

Couples looking for a cozy retreat may also enjoy the Best Western Plus Santee Inn, which, while slightly lower on the review scale at 8.8, boasts a charming atmosphere with an indoor hot tub and kitchen facilities for added convenience.

Each of these hotels provides a friendly and accommodating experience, allowing travelers to focus on their adventures while enjoying quality service without stretching their budget. View all budget hotels in Santee.
When is the best time to go to Santee?
The most popular time to visit Santee is April, when the weather is pleasantly warm, with temperatures typically ranging from the mid-70s to low 80s Fahrenheit. This delightful climate makes it superb for enjoying the area's outdoor activities, such as hiking, golfing, or simply relaxing in one of the beautiful parks.

During the peak season from March to May, Santee attracts visitors who appreciate the vibrant atmosphere and opportunities for adventure. This is an ideal time to explore the stunning landscapes and partake in local events. With the pleasant temperatures, you can comfortably enjoy activities like picnicking at Santee Lakes or taking scenic walks along the trails.

For travelers who enjoy a bit of tranquility and still want to experience the charm of Santee, November presents a wonderful alternative. While it's considered a low season, the weather remains mild, allowing for enjoyable outdoor activities without the crowds. This time of year is superb for connecting with nature, as the fall colors create a picturesque backdrop for your explorations.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santee.
How can I save on a Santee hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santee hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santee hotel?
Prices for hotels in Santee often vary, but you can find a great deal from $46 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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